Author(s):
Bishwanath Mishra, Sujit Dash, Amaresh Chandra Sahoo, Prabhat Kumar Sahoo, Sazia Tabasum
Email(s):
tuku_bm@yahoo.co.in
DOI:
10.52711/0974-360X.2021.00640
Address:
Bishwanath Mishra*, Sujit Dash, Amaresh Chandra Sahoo, Prabhat Kumar Sahoo, Sazia Tabasum
Institute of Pharmacy and Technology, Salipur, Cuttack, Odisha- 754202, India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 7,
Year - 2021
ABSTRACT:
Mimusops elengi Linn. is a plant with high medicinal and commercial value. Although several secondary metabolites have been reported from different species of this plant, there has been not much information available on the complete profile of phytochemical constituents in Mimusops elengi Linn. The HPTLC fingerprinting of methanol extract showed 6 peaks having maximum Rf values 0.10, 0.27, 0.34, 0.51, 0.72, and 0.80 at 254nm. The same extract showed 3 peaks having maximum Rf value 0.25, 0.29 and 0.49 at 366 nm. This study applies Gas chromatography-Mass spectrometry technique to determine the possible chemical components in the methanol extract of Mimusops elengi Linn. Unripened fruits reports for the first time most extensive profile of the plant. The determination and identification of bioactive chemical compounds is established and based on the peak area, retention time molecular weight, and molecular formula. GC-MS analysis of Mimusops elengi Linn. revealed the existence of the 2,2’ Methylenebis [3,4,6-trichloroanisole] which was found to be major component followed by Z-1,9-Hexadecadiene, Cyclopentaneundecanoic-acid, 4-Methyloctanoic acid and E-10-Dodecen-1-ol propionate. The results obtained may be helpful to the further study of pharmacological action for their promising utilization as therapeutic agents.
Cite this article:
Bishwanath Mishra, Sujit Dash, Amaresh Chandra Sahoo, Prabhat Kumar Sahoo, Sazia Tabasum. Phytochemical Assessment of Mimusops elengi Linn. Unripe fruits Methanol extracts using Modern Analytical Technique. Research Journal of Pharmacy and Technology. 2021; 14(7):3700-4. doi: 10.52711/0974-360X.2021.00640
Cite(Electronic):
Bishwanath Mishra, Sujit Dash, Amaresh Chandra Sahoo, Prabhat Kumar Sahoo, Sazia Tabasum. Phytochemical Assessment of Mimusops elengi Linn. Unripe fruits Methanol extracts using Modern Analytical Technique. Research Journal of Pharmacy and Technology. 2021; 14(7):3700-4. doi: 10.52711/0974-360X.2021.00640 Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-7-37
REFERENCE:
1. Kirthikar KR, Basu BD. Indian Medicinal Plants, 2nd ed.; Popular Publications: Dehradun, 1999.
2. Satyapal U, Mahajan D, Tatke P, Naharwar V. Phytochemical Investigation and Assessment of Antioxidant and Antimicrobial Potential of Bark of Mimusops elengi. Research Journal of Pharmacy and Technology. 2014; 7(11): 1226-1230.
3. Sharma H, Karnwal A. Impact of Herbal Extracts in Biocontroling of Four Human Pathogenic Bacteria- an in-vitro Study. Research Journal of Pharmacy and Technology. 2018; 11(7): 2895-2900.
4. Marchese A, Shito GC. Resistance patterns of lower respiratory tract pathogens in Europe. International Journal of Antimicrobial Agents. 2001; 16(1): 25-29.
5. Poole K. Overcoming antimicrobial resistance by targeting resistance mechanisms. The Journal of Pharmacy and Pharmacology. 2001; 53 (3): 283-94.
6. Amani S et al. Antimicrobial activities in some argentine medicinal plants. Acta Horticulture 1998; 501: 115-122
7. Salvat A et al. Screening of some plants from Northern Argentina for their antimicrobial activity. Letters in Applied Microbiology. 2001; 32(5): 293-97.
8. Harborne JB. Phytochemical methods. Edn 3rd London, Chapman and Hall, 1998, pp. no-1-28.
9. Wagner H, Baldt S, Zgnaisnki EM. Plant drug analysis, New York, Berlin, Springer, 1996; 355-357.
10. Daharwal SJ, Shrivastava S. Preliminary Phytochemical Screening and HPTLC Fingerprinting of Extracts of Thuja occidentalis. Research Journal of Pharmacy and Technology. 2019; 12(10): 4782-4784.
11. Anto Arockia Raj A, Vinnarasi J, Venkataraman R, Augustin M. HPTLC Fingerprinting Analysis of Tannin Profile on Canthium coromandelicum and Flueggea leucopyrus willd. Research Journal of Pharmacy and Technology. 2018; 11(12): 5355-5358.
12. Patel GH, Prajapati ST, Patel CN. HPTLC Method Development and Validation for simultaneous Determination of Cinitapride and Pantoprazole in Capsule Dosage Form. Research Journal of Pharmacy and Technology. 2011; 4(9): 1428-1431.
13. Patidar P, Singh S, Dubey D, Dashora K. Estimation of Rutin in Tephrosia purpurea by HPTLC Method. Research Journal of Pharmacy and Technology. 2013; 6(1): 58-60.
14. Moualla N, Naser M. Using GC/MS to Study the Chemical Composition of Essential Oil of Thymus vulgaris L. at AL-Qadmous Area, Syria. Research Journal of Pharmacy and Technology. 2015; 8(4): 437-442.
15. Priya S, Nethaji S, Sindhuja B. GC-MS Analysis of Some Bioactive Constituents of Diospyros virginian. Research Journal of Pharmacy and Technology. 2014; 7(4): 429-432.
16. Aravind R, Bindu AR, Bindu K, Alexeyena V. GC-MS Analysis of the Bark Essential Oil of Cinnamomum malabatrum (Burman. F) Blume. Research Journal of Pharmacy and Technology. 2014; 7(7): 754-759.
17. http://www.thegoodscentscompany.com/data/rw1552251.html
18. Hussein J, Hameed IH, Hadi I, Mohammed. Using Gas Chromatography-Mass Spectrometry (GC-MS) Technique for Analysis of Bioactive Compounds of Methanolic Leaves extract of Lepidium sativum. Research Journal of Pharmacy and Technology. 2017; 3981-3989.