Author(s): Krishn Kumar Agrawal, Nitin Agrawal, Nidhi Jadon, Kuldeep Gangwar, Swarnim Jain, Nitin Sharma, Jyoti

Email(s): bbau27verma@gmail.com

DOI: 10.52711/0974-360X.2021.00617   

Address: Krishn Kumar Agrawal1, Nitin Agrawal1, Nidhi Jadon1, Kuldeep Gangwar1, Swarnim Jain1, Nitin Sharma1, Jyoti2*
1Faculty of Pharmacy, R.B.S. Engineering Technical Campus, Bichpuri, Agra (U.P.) - 283105.
2Institute of Pharmaceutical Research, GLA University, Mathura (U.P.) - 281406.
*Corresponding Author

Published In:   Volume - 14,      Issue - 7,     Year - 2021


ABSTRACT:
Objective: The study was planned to investigate the extractive value and in-vitro anti-urolithiatic activity of different extracts of Embelia ribes Burn. F. and Ipomea hederacea Jacq seeds. Methods: Phytochemical analysis was undertaken to evaluate the phyto-constituents present in different extracts. The extracts were prepared by the maceration process. The in-vitro anti-urolithiatic activity was performed by dissolution and turbidity methods. Result: The extractive value of chloroform, ethanol, diethyl ether, n-hexane, acetone and water of Embelia ribes and Ipomea hederacea was found to be 2%, 2.5%, 2.5%, 2%, 1.5%, 1%w/w and 1.5%, 2%, 2.4%, 14%, 2%, 6% w/w respectively. The result of phytochemical analysis showed that aqueous, ethanolic, chloroform, diethyl ether, n-hexane and acetone extract of Embelia ribes and Ipomea hederacea have positive for alkaloids, proteins, carbohydrates, amino acids, tannins, protein, mucilage and glycoside. Moreover the result of anti-urolithiatic activity of ethanol and hexane extract of Embelia ribes and Ipomea hederacea were found to be 84.33±0.67%, 76.67±0.67%, 72.33±0.88 NTU and 73.00±1.15 NTU by dissolution and turbidity methods respectively. Conclusion: On the basis of result analysis, we can conclude that both the plants extract have anti-urolithiatic activity but ethanol and hexane extract have much significant activity than other extracts when compared to standard cystone.


Cite this article:
Krishn Kumar Agrawal, Nitin Agrawal, Nidhi Jadon, Kuldeep Gangwar, Swarnim Jain, Nitin Sharma, Jyoti. Determination of Extractive Value, Phytochemical Constituents and In-Vitro Anti-Urolithiatic Activity of Embelia ribes Burm. F. and Ipomea Hederacea Jacq. Research Journal of Pharmacy and Technology. 2021; 14(7):3566-0. doi: 10.52711/0974-360X.2021.00617

Cite(Electronic):
Krishn Kumar Agrawal, Nitin Agrawal, Nidhi Jadon, Kuldeep Gangwar, Swarnim Jain, Nitin Sharma, Jyoti. Determination of Extractive Value, Phytochemical Constituents and In-Vitro Anti-Urolithiatic Activity of Embelia ribes Burm. F. and Ipomea Hederacea Jacq. Research Journal of Pharmacy and Technology. 2021; 14(7):3566-0. doi: 10.52711/0974-360X.2021.00617   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-7-14


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