Author(s): Nageeb AGM Hassan, Sabrina Ait Gacem, Afnan Abdul-Hameed Al-Qaysi, Maryam Jaafar AlAani

Email(s): sabrinaaitgacem@yahoo.com

DOI: 10.52711/0974-360X.2021.00590   

Address: Nageeb AGM Hassan, Sabrina Ait Gacem*, Afnan Abdul-Hameed Al-Qaysi, Maryam Jaafar AlAani
College of Pharmacy and Health Sciences, Ajman University, Ajman, UAE.
*Corresponding Author

Published In:   Volume - 14,      Issue - 6,     Year - 2021


ABSTRACT:
Background: Most of individuals do not prefer consulting a physician when they suffer from mild to moderate pain or fever and they tend to get over the counter drugs (OTC) from the pharmacy. Non-steroidal anti-inflammatory (NSAIDs) consumption pattern and self-medication behavior is a common practice especially during adolescence. Many self-medication behaviors were observed from individuals especially students which use NSAIDs frequently and that might lead to some unwanted effects due to improper knowledge and awareness. Although NSAIDs are considered as safe medications in general, but serious side effects are still present and can affect different parts of the body. Objectives: Our study aims to assess the correlation between several types of pain and self-medication pattern of Paracetamol and NSAIDs among university students in UAE. Methods: This was a cross-sectional study that was conducted among individuals aged 17 years and above from different nationalities and specialties from June till July 2018. The data were obtained through a validated self-administrated questionnaire that was distributed as a hardcopy as well as online. Data collection took place in UAE universities targeting 345 university students. The data were analyzed using SPSS version 20 and the results were considered significant at the 0.05 level with a 95% Confidence interval. Results: The current study results show that (67%) of individuals use pain medications to relief pain associated with headache. The majority of individuals reported that they suffer from pain at least one day weekly (26.4%). The pain that mostly led individuals to take pain medications is headache and it is accounts for (67%). The most frequently used pain medication is Paracetamol (80.9%) followed by Ibuprofen, Mefenamic acid and Diclofenac (35.4%, 17.1% and 13.6%) respectively. It was observed that (28.4%) of individuals use more than one pain medication at the same time. The results show that there was a significant correlation between the intake of Mefenamic acid for pain and individuals that reported the use of pain medications for menstrual pain [p=0.000, OR: 5.223, 95% CI: 2.73 - 9.96]. The significant intake of Aspirin for back pain [p=0.020, OR: 3.239, 95% CI: 1.159 - 9.05] and Diclofenac for both muscles pain and back pain back pain [p=0.000, OR: 3.061, 95% CI: 1.792 - 5.228), p=0.000, OR: 3.037, 95% CI: 1.789 - 5.15 respectively] and Paracetamol for both toothache and fever [p=0.002, OR: 1.220, 95% CI: 1.120 - 1.32 and p=0.044, OR: 1.137, 95% CI: 1.027 - 1.259 respectively]. The following NSAIDs showed a significant correlation with the intake of pain medications for toothache: Aspirin [p=0.018, OR: 3.167, 95% CI: 1.171 - 8.56], Ibuprofen [p=0.004, OR: 1.618, 95% CI: 1.201 - 2.17] and Diclofenac [p=0.000, OR: 2.692, 95% CI: 1.591 - 4.55]. Only Paracetamol was found to have a significant correlation for the use during fever [p=0.044, OR: 1.137, 95% CI: 1.027 - 1.259] while other pain medications were found to have a negative correlation. Conclusion: The majority of respondents use the pain medications to relief headache and the most frequently used pain medication was Paracetamol. A significant correlation was observed between the intake of Mefenamic acid for pain and individuals that reported the use of pain medications for menstrual pain as well as Aspirin intake for back pain, Diclofenac for muscles pain and back pain. Only Paracetamol was found to have a significant correlation for the use during fever while other pain medications were found to have a negative correlation.


Cite this article:
Nageeb AGM Hassan, Sabrina Ait Gacem, Afnan Abdul-Hameed Al-Qaysi, Maryam Jaafar AlAani. Prevalence of pain and self-medication pattern of Paracetamol and NSAIDs among university students in United Arab Emirates. Research Journal of Pharmacy and Technology. 2021; 14(6):3393-8. doi: 10.52711/0974-360X.2021.00590

Cite(Electronic):
Nageeb AGM Hassan, Sabrina Ait Gacem, Afnan Abdul-Hameed Al-Qaysi, Maryam Jaafar AlAani. Prevalence of pain and self-medication pattern of Paracetamol and NSAIDs among university students in United Arab Emirates. Research Journal of Pharmacy and Technology. 2021; 14(6):3393-8. doi: 10.52711/0974-360X.2021.00590   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-6-80


REFERENCES:
1.    Gyawali S, Shankar PR, Poudel PP, Saha A. Knowledge, attitude and practice of self-medication among basic science undergraduate medical students in a medical school in western Nepal. Journal of clinical and diagnostic research: JCDR. 2015;9(12):17. Available at: https://doi.org/10.7860/JCDR/2015/16553.6988
2.    Al-Shahwan MJ, Gacem SA, Hassan NA, Djessas F, Jairoun AA, Al-Hemyari SS. A study to identify the most common reasons to wean among breastfeeding mothers in UAE. J Pharm Bioall Sci 2020; 12: 72-6. Available at: https://doi.org/10.4103/ jpbs.JPBS_230_19
3.    Isam MW, AlShehhi K, Gacem SA. Assessment of the Consumers’ Attitude towards Leftover and Expired Medications at Homes. Research Journal of Pharmacy and Technology. 2019;12(11):5182-8. Available at: https://doi.org/10.5958/0974-360X.2019.00897.7
4.    Bloukh S, Edis Z, Islam MW, Gacem SA, Saeed L, Sultan A. Assessment of depression status among adolescents and adults in UAE. International Research Journal of Pharmacy. 2019;10(5):23-26. Available at: https://doi.org/10.7897/2230-8407.1005156
5.    Luo X, Pietrobon R, Curtis LH, Hey LA. Prescription of nonsteroidal anti-inflammatory drugs and muscle relaxants for back pain in the United States. Spine. 2004;29(23):531-7. Available at: https://doi.org/10.1097/01.brs.0000146453.76528.7c
6.    Al-shahwan M, Gacem SA, Shamseddin S, Sammour M. Vitamin D impact on human health and its relation with several diseases. Int J Appl Pharm. 2018; 10: 60. Available at: https://doi.org/ 10.22159/ijap.2018v10i6.28776
7.    American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd ed). Washington, DC: APA.
8.    Hawton K, Bergen H, Simkin S, Dodd S, Pocock P, Bernal W, Gunnell D, Kapur N. Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses. Bmj. 2013; 346: 403. Available at: https://doi.org/10.1136/bmj.f403
9.    Adamek E, Jakubczyk J, Baran W, Makowski A, Lipska I, Ziemia J et al. Photodegradation of the selected anti-inflammatory drugs in the aquatic environment. Proceedings of ECOpole. 2011; 5(1): 147.
10.    Gene E, Calvet X, Moron A, Iglesias ML. Recommendations for the use of anti-inflammatory drugs and indications for gastrointestinal protection in emergency departments. Emergencias. 2009; 21: 295-300. Available at: https://doi.org/ 10.1016/B978-032305475-1.50041-0
11.    Corrêa M, Soares M, Muccillo-Baisch A. Self-medication in university students from the city of Rio Grande, Brazil. BMC Public Health. 2012;12(1):339. Available at: https://doi.org/ 10.1186/1471-2458-12-339
12.    Tahir MU, Shoaib N, Usman A, Sadiq S, Harris NI. Prevalence of Analgesic use amongst university students. PJMHS. 2011; 5(4): 775-7.
13.    Awaluddin SM, Ahmad NA, Naidu BM, Yusof M, AbdRazak MA, Ghani MKAA. Prevalence of non-steroidal anti-inflammatory drugs (NSAIDs) use in Malaysian adults and associated factors: A population-based survey. Malaysian J Public Heal Med. 2017;17(3):58–65. Available at: https://doi.org/10.37268/mjphm/ vol.17/no.3/art.229
14.    Gadomski A.: Nonsteroidal anti-inflammatory drugs in the medicine cabinet. Med Rodzinna. 2006; 2: 37.
15.    Sarganas G, Buttery AK, Zhuang W, Wolf IK, Grams D, Rosario AS, et al. Prevalence, trends, patterns and associations of analgesic use in Germany. BMC Pharmacology and Toxicology. 2015; 16(1): 28. Available at: https://doi.org/10.1186/s40360-015-0028-7
16.    Mijatović V, Ćalasan J, Horvat O, Sabo A, Tomić Z, Radulović V. Consumption of non-steroidal anti-inflammatory drugs in Serbia: a comparison with Croatia and Denmark during 2005–2008. European journal of clinical pharmacology. 2011; 67(2): 203-7. Available at: https://doi.org/10.1007/s00228-010-0951-x
17.    Abu-Gharbieh E, Fahmy S, Basheti BA, Mohammad M, Bustanji Y. Prevalence of Aspirin Use and Its Concurrent Use with Ibuprofen among Two Middle Eastern Countries: Jordan and the UAE- A Cross Sectional Study. Jordan Journal of Pharmaceutical Sciences. 2011; 4(3): 155-165.

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