Author(s): Ali Jabbar Radhi, Dhurgham Qasim Shaheed, Mohammed Hamza Heriz, Zeyad Kadhim Oleiwi

Email(s): Alijebar56@gmail.com

DOI: 10.52711/0974-360X.2021.00587   

Address: Ali Jabbar Radhi1*, Dhurgham Qasim Shaheed1, Mohammed Hamza Heriz1, Zeyad Kadhim Oleiwi2
1College of Pharmacy, University of Al-Kafeel, Najaf, Iraq.
2Altoosi University College, Najaf, Iraq.
*Corresponding Author

Published In:   Volume - 14,      Issue - 6,     Year - 2021


ABSTRACT:
A series of new polymer of barbiturate containing tetrazole ring were synthesized by Click polymerization between diazido and dinitrile derivatives in the existence of NH4Cl as catalyst. The polymers structure were confirmed by several techniques, IR and NMR spectroscopy. The end polymers possess high solubility at room temperatures in aprotic polar solvents for example DMSO and DMF. Thermal properties and stability of the new polymers were analyzed by using two thermal analysis are (TGA) and (DSC) which showed that the polybarbiturate containing tetrazole ring possess Tg value (149–187°C) and excellent thermal stability. The new polytetrazole polymers were screened antibacterial activity by using some kinds strains of Gram-negative and Gram-positive bacteria. The tested polymers displayed good significant against these bacteria.


Cite this article:
Ali Jabbar Radhi, Dhurgham Qasim Shaheed, Mohammed Hamza Heriz, Zeyad Kadhim Oleiwi. Preparation and Study Biological Activity of Polybarbiturate Linked Tetrazole Ring. Research Journal of Pharmacy and Technology. 2021; 14(6):3377-9. doi: 10.52711/0974-360X.2021.00587

Cite(Electronic):
Ali Jabbar Radhi, Dhurgham Qasim Shaheed, Mohammed Hamza Heriz, Zeyad Kadhim Oleiwi. Preparation and Study Biological Activity of Polybarbiturate Linked Tetrazole Ring. Research Journal of Pharmacy and Technology. 2021; 14(6):3377-9. doi: 10.52711/0974-360X.2021.00587   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-6-77


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