Author(s): Patel Minesh, G.S. Chakraborthy

Email(s): minesh.ad99@gmail.com

DOI: 10.52711/0974-360X.2021.00560   

Address: Patel Minesh*, G.S. Chakraborthy
Department of Pharmacology, Parul Institute of Pharmacy and Research, Parul University, Waghodia, Vadodara 391760, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 6,     Year - 2021


ABSTRACT:
Clinical trials are essence for the progress of new treatments. Whether a person should engage confide in on their compassionate of the liability and gain for themselves and for society as an entity. Clinical trials are research review in which people volunteer to attempt major treatments, interventions or experiment as a means to forbid, detect, evaluate or manage assorted diseases or medical conditions. Some investigations glance at how people react to a new arbitration and what side effects valor occur. Every new medicine and treatment initiated with volunteers engage in clinical trials. We incur our present high ideal of medical care to studies that have been operate in the past under guidance of the INDIAN Food and Drug Administration (FDA). In addition to Research on new drugs and devices, clinical trials bring a scientific footing for urge and treating patients. Even when researchers do not achieve the conclusion they anticipate; trial results can help point scientists in the mend direction. Blood pressure is great because the larger than your blood pressure is, the larger than your risk of health problems in the future. If your blood pressure is higher than it is putting extra ache on your arteries and on your heart. High blood pressure clouts your heart to work higher to pump blood to the comfort of your body. This causes part of your heart (left ventricle) to congeal. A congeal left ventricle high your risk of heart attack, heart failure and sudden cardiac death. Heart failure. The arena for clinical trials of hypertension management is in transition. The stage of mega trials may not be bygone but is assuredly in decline. Incremental growth in the therapies assessable in the face of a high global disease hardship has imply that hypertension researchers have also attract on getting beat efficacy and value from the available treatments through arrangement improvement, combinations, and algorithms. There has been go on amuse in the role of nonpharmacological compute in cure and management of hypertension.


Cite this article:
Patel Minesh, G.S. Chakraborthy. A Role of Clinical Trial in Management of Hypertension and Medication of Hypertension. Research Journal of Pharmacy and Technology. 2021; 14(6):3215-2. doi: 10.52711/0974-360X.2021.00560

Cite(Electronic):
Patel Minesh, G.S. Chakraborthy. A Role of Clinical Trial in Management of Hypertension and Medication of Hypertension. Research Journal of Pharmacy and Technology. 2021; 14(6):3215-2. doi: 10.52711/0974-360X.2021.00560   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-6-50


REFERENCE:
1.    Ikechi G Okpechi1 and Brian L Rayner, Impact of recent landmark clinical trials on hypertension treatment, 2011; Future Science Group; Clin. Invest. (2011) 1(8), 1141–1154
2.    Robert M. Carey, Paul Muntner, Hayden B. Bosworth and Paul K. Whelton; Cure and Control of Hypertension JACC Health Promotion Series; September 2018; Journal of the American College of Cardiology; Volume 72; Issue 11, September 2018
3.    Bryan Williams, MD, FRCP, FAHA Leicester; Recent Hypertension Trials Implications and Fuss; 2005; Journal of the American College of Cardiology; Vol. 45, No. 6, 2005
4.    Norman M. Kaplan; Clinical Trials for Hypertension Expectations Fulfilled and Unfulfilled; Hypertension Division, Department of Internal Medicine, University of Texas; 2007; accepted November 9, 2006.
5.    Thomas D. Giles, MD; Barry J. Materson, MD; Jay N. Cohn, MD;3John B. Kostis, MD; Definition and Classification of Hypertension: An Update; 2009; The Journal of Clinical Hypertension; VOL. 11 NO. 11 November 2009.
6.    Jamie Kitt, Rachael Fox, Katherine L. Tucker, and Richard J. McManus; New Approaches in Hypertension Management: a Review of Current and Developing Technologies and Their Potential Impact on Hypertension Care; 2019; US National Library of Medicine National Institute of Medicine; PMCID: PMC6483962
7.    Clinical Practice Guidelines: Management of Hypertension 4th Edition; ISBN 978-967-12406-0-1; MOH/P/PAK/272.13(GU)
8.    https://www.heart.org/en/health-topics/high-blood-pressure/changes-you-can-make-to-manage-high-blood-pressure/types-of-blood-pressure-medications
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11.    https://www.drugbank.ca/drugs/DB00661
12.    Rajkumar Bharatia, Manoj Chitale, Ganesh Narain Saxena, Raman Ganesh Kumar, Chikkalingaiah, Abhijit Trailokya, Kalpesh Dalvi, Suhas Talele; Management Practices in Indian Patients with Uncontrolled Hypertension; 2016; Journal of The Association of Physicians of India; Volume. 64 July 2015.
13.    Daniel T. Lackland, DrPH; Robert M. Carey, MD; Adriana B. Conforto, MD, PhD; Clive Rosendorff, MD, PhD; Paul K. Whelton, MD; Philip B. Gorelick, MD; Implications of Recent Clinical Trials and Hypertension Guidelines on Stroke and Future Cerebrovascular Research; 2018; American Heart Association, Inc.; DOI: 10.1161/STROKEAHA.117.019379.
14.    Ikechi G Okpechi1 and Brian L Rayner, Impact of recent landmark clinical trials on hypertension treatment, 2011; Future Science Group; Clin. Invest. (2011) 1(8), 1141–1154

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