Author(s): Kedar Tejashree R., Dashetwar A.R., Kardile D.P., Jadhav A.P., Bhagat V.C., Shete R.V.

Email(s): tejashrikedar@gmail.com

DOI: 10.52711/0974-360X.2021.00554   

Address: Kedar Tejashree R.*, Dashetwar A.R., Kardile D.P., Jadhav A.P., Bhagat V.C., Shete R.V.
Department of Pharmaceutical Quality Assurance, Rajgad Dnyanpeeth’s College of Pharmacy, Bhor, Tal. Bhor, Dist. Pune, Maharashtra.
*Corresponding Author

Published In:   Volume - 14,      Issue - 6,     Year - 2021


ABSTRACT:
A new, simple, accurate, precise and reproducible UV-Spectrophotometric method is being developed for the simultaneous estimation of Metformin Hydrochloride and Voglibose in tablet dosage form. The stock solutions were prepared in methanol. The ?max for Metformin Hydrochloride and Voglibose were found to be248 nm and 287nm respectively. The Metformin Hydrochloride and Voglibose obeyed Beer’s law in concentration range of 8-16µg/ml and 4-20µg/ml respectively. Results of analysis of absorbance ratio method were analysed and validated for various parameters according to ICH guidelines for accuracy, precision, linearity, robustness, LOD and LOQ. The proposed method is highly sensitive, precise and accurate, therefore can be used for intended purpose.


Cite this article:
Kedar Tejashree R., Dashetwar A.R., Kardile D.P., Jadhav A.P., Bhagat V.C., Shete R.V. Q-Absorbance Ratio Spectrophotometric Method for the Simultaneous Estimation of Metformin Hydrochloride and Voglibose in Tablet Dosage form. Research Journal of Pharmacy and Technology. 2021; 14(6):3179-3. doi: 10.52711/0974-360X.2021.00554

Cite(Electronic):
Kedar Tejashree R., Dashetwar A.R., Kardile D.P., Jadhav A.P., Bhagat V.C., Shete R.V. Q-Absorbance Ratio Spectrophotometric Method for the Simultaneous Estimation of Metformin Hydrochloride and Voglibose in Tablet Dosage form. Research Journal of Pharmacy and Technology. 2021; 14(6):3179-3. doi: 10.52711/0974-360X.2021.00554   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-6-44


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