Fouzia Tehseen, Syed Safiullah Ghori, Mohammed Dawood, Shafia Tazeen, Kulsum Sara, Abdul Samad
Fouzia Tehseen1*, Syed Safiullah Ghori2, Mohammed Dawood1, Shafia Tazeen1, Kulsum Sara1, Abdul Samad3
1Department of Pharmaceutical Chemistry, Anwarul Uloom College of Pharmacy,
Hyderabad, Telangana, India, 500008.
2Department of Pharmacology, Anwarul Uloom College of Pharmacy, Hyderabad, Telangana, India, 500008.
3Research Scholar, Government Nizamia Tibbi College, Charminar, Hyderabad, Telangana, India, 500008.
Volume - 14,
Issue - 5,
Year - 2021
Ayurveda is the ancient Indian system of medicine which includes the usage of natural and mechano procedures to eliminate the root cause of the disease. Ayurvedic system of medicine is economical, easily available and free of side effects which make it beneficial to human beings. Among various diseases, a large population is infected with helminthiasis which can be treated by using medicinal plants. In the present study we developed a novel polyherbal formulation (PHF) containing a mixture of powdered Artemesia absinthium (shoot), Butea Monosperma (leaves), Ipomea headeraceae (seeds), Hyocyamus niger (seeds). Phytochemical screening of the extract indicated the presence of carbohydrates, amino acids, tannins, sterols and alkaloids the polyherbal formulation was studied for its anthelmintic activity using Indian earthworm (Pheritima posthuma) as the test model. Albendazole was taken as the standard reference drug. The petroleum ether and aqueous extracts with the petroleum ether and methanolic extract. of the PHF of different concentrations (25µg/ml, 50µg/ml, 100µg/ml) were prepared and used to determine the paralysis time and death time of the worms. The petroleum ether and methanolic extract of the PHF has shown significant activity due to presence of various phytoconstituents like tannins, flavonoids and alkaloids. In the course of our investigation, we found that the 100µg/ml methanolic extract has better anthelmintic activity when compared to the other concentrations checked.
Cite this article:
Fouzia Tehseen, Syed Safiullah Ghori, Mohammed Dawood, Shafia Tazeen, Kulsum Sara, Abdul Samad. Phytochemical Screening and Invitro Anthelmintic Activity of a Novel Polyherbal Formulation. Research Journal of Pharmacy and Technology. 2021; 14(5):2742-4. doi: 10.52711/0974-360X.2021.00483
Fouzia Tehseen, Syed Safiullah Ghori, Mohammed Dawood, Shafia Tazeen, Kulsum Sara, Abdul Samad. Phytochemical Screening and Invitro Anthelmintic Activity of a Novel Polyherbal Formulation. Research Journal of Pharmacy and Technology. 2021; 14(5):2742-4. doi: 10.52711/0974-360X.2021.00483 Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-5-67
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