Author(s):
Nitin A. Mirgane, Arun Chandore, Vitthal Shivankar, Yashwant Gaikwad, Gurumeet C. Wadhawa
Email(s):
wadhava.gurumeet@gmail.com
DOI:
10.52711/0974-360X.2021.00474 
Address:
Nitin A. Mirgane3, Arun Chandore2, Vitthal Shivankar4, Yashwant Gaikwad, Gurumeet C. Wadhawa1*
1Rayat Shikshan Sansthas Karmaveer Bhaurao Patil College Vashi Sector 15 A Navi Mumbai,
400703, Maharashtra, India.
2Abasaheb Marathe Arts and New Commerce, Science College, Rajapur - 416702.
District- Ratnagiri (Maharashtra), India.
3Post Graduate Department of Chemistry, SIES College of ASC, Sion (West) Affiliated to University of Mumbai, Mumbai - 400022, Maharashtra, India.
4Rayat Shikshan Santhas, Chatrapati Shivaji College , Satara
*Corresponding Author
Published In:
Volume - 14,
Issue - 5,
Year - 2021
ABSTRACT:
Typhonium flagelliforme from the family Araceae is very rare plant. It is very good curative and work against various illness and infections. The plant part has large importance in Ayurveda. In this study we use stem and leaves used for phytochemical analysis and their biological properties such as Antioxidant and Anti-inflammatory activity. Known Protocol for the phytochemical analysis, while antioxidant and anti-inflammatory activity was determined using known methods. Both the leaves and stem extract show presence of various important active constituent and shows better activity against the free radicals or antioxidant activity or they can show the anti-inflammatory activity.
Cite this article:
Nitin A. Mirgane, Arun Chandore, Vitthal Shivankar, Yashwant Gaikwad, Gurumeet C. Wadhawa. Phytochemical Study and Screening of Antioxidant, Anti-inflammatory Typhonium Flagelliforme. Research Journal of Pharmacy and Technology. 2021; 14(5):2686-0. doi: 10.52711/0974-360X.2021.00474
Cite(Electronic):
Nitin A. Mirgane, Arun Chandore, Vitthal Shivankar, Yashwant Gaikwad, Gurumeet C. Wadhawa. Phytochemical Study and Screening of Antioxidant, Anti-inflammatory Typhonium Flagelliforme. Research Journal of Pharmacy and Technology. 2021; 14(5):2686-0. doi: 10.52711/0974-360X.2021.00474 Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-5-58
REFERENCES:
1. David JP, Meira M, David JM, Brandão N, Branco A, Agra MF, Barbosa MRV, De Quiroz LP, Giulietti AM. Radical scavenging, antioxidant and cytotoxic activity of Brazilian Caatinga plants. Fitoterapia. 2007; 78: 215-218.
2. Galeano MP, Bernal RG. Guía de las plantas del Parque Regional Natural Ucumarí. Tomo I. Carder. Pereira: Editorial Graficas Buda Ltda. 1993.
3. Golden TR, Hinerfeld DA, Melov S. Oxidative stress and aging: beyond correlation. Aging Cell. 2002; 1: 117-123.
4. Koosirirat C. Anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients. Int Immuno-Pharmacol 2010; 10(7): 815-818.
5. Buragohain J. Ethnomedicinal Plants used by the ethnic Communities of Tinsukia District of Assam, India. Rec Res Sci and Tech 2011; 3(9): 31-42.
6. Thawkar B, Kale M, Oswal M, Maniyar K, Kadam K, Kamat S. To study Anti-inflammatory activity of 70% Methanolic Extract of Triumfetta rhomboidea: In Vitro Study. Research J. Pharm. and Tech. 9(3); 2016: 241-244. doi: 10.5958/0974-360X.2016.00044.5
7. Gonçalves C, Dinis T, Batista MT. Antioxidant properties of proanthocyanidins of Uncaria tomentosa bark decoction: a mechanism for anti-inflammatory activity. Phytochemistry. 2005; 66: 89-98.
8. Pavithra S, Banu N. Free Radical Scavenging Activity and Total Antioxidant Capacity of Tin Chlorophyllin from Morinda citrifolia L. Research J. Pharm. and Tech. 2017; 10(2): 453-455. doi: 10.5958/0974-360X.2017.00091.9
9. Hsuan K, Chin SC & Tan HTW. The Concise Flora of Singapore: Monocotyledons. 1998; 2: 215-245.
10. Li BY, Jian T. Flora of China. Typhonium flagelliforme (Loddiges) Blume, Rumphia. 1: 134. 1837. 23:1, 34, 35.
11. Ara H. An Annotated Checklist of Aroids of Bangladesh. Bangladesh Journal of Plant Taxonomy. 2001; 8(2): 19-34.
12. Hagawane TN, Mahuvakar AM, Gaikwad RV, Kshirsagar NA. Oleic Acid Induced Acute Lung Injury/Acute Respiratory Distress Syndrome Animal Model. Research J. Pharm. and Tech. 2014; 7(8): 882-888.
13. Govaerts R & Frodin DG. World Checklist and Bibliography of Araceae (and Acoraceae): The Board of Trustees of the Royal Botanic Gardens, Kew. 2002; 1-560.
14. Sharma R, Kumar U. Exploration and Phytochemical Estimation of Murraya koenigii Leaves for Pharmaceutical Applications. Asian J. Pharm. Res. 2019; 9(3): 159-168.
15. Byahatti VV, Khan AM, Patil SH, Choudhury A. Preliminary Phytochemical Investigation and In-vitro Antioxidant Activity of Bergenia ciliata Leaves. Research J. Pharm. and Tech. 2010; 3(2): 399-401.
16. Sabarinath C, Sudhakar P, Shanmuganath C. Phytochemical and Antibacterial screening on leaves of Solanum torvum. Asian J. Res. Pharm. Sci. 2018; 8(3): 130-132.
17. MahadevaRao US, Mohd KS, Abd Halim SZB, Khamis MB. Screening of Phytochemicals and Comparative Antioxidant activity of Leaf and Fruit of MalaysianMengkudu Using Aqueous and Organic Solvent Extracts. Research J. Pharm. and Tech. 2013; 6(9): 1064-1072.
18. Bhavani R, Bhuvaneswari E, Rajeshkumar S. Antibacterial and Antioxidant activity of Ethanolic extract of Ceiba pentandra leaves and its Phytochemicals Analysis using GC-MS. Research J. Pharm. and Tech 2016; 9(11):1922-1926. doi: 10.5958/0974-360X.2016.00393.0
19. Nair DU, Saraswathy MP, Narra Kishore N, Reddy Pully N. Phytochemical and Antimicrobial Evaluation of Luffa cylindrica Linn. Leaf and Flower Extracts – An In-Vitro Study. Research J. Pharm. and Tech. 2010; 3(2): 438-441.
20. Harborne JB. Phytochemical methods: a guide to modern techniques of plant analysis. London: Chapman and Hall. 1980.
21. Srivastava J, Lambert J, Vietmeyer N. Medicinal plants: An expanding role in development. World bank Technical paper. No. 320. 1996.
22. Muzushima Y, Kabayashi M. Interaction of anti‐inflammatory drugs with serum proteins, especially with some biologically active proteins. J Pharm Pharmacol, 1968; 20: 169-173.
23. Elias G, Rao MNA. Inhibition of albumin denaturation and antiinflammatory activity of dehydrozingerone and its analogs. Indian J Exp Biol, 1988; 26: 540-542.
24. Yusuf AZ, Zakir A, Shemau, Z. Phytochemical analysis of the methanol leaves extract of Paullinia pinnata linn. Journal of Pharmacognosy and Phytotherapy 2014; 6(2): 10-16.
25. Gavali LV, Shivankar VS, Gaikwad YA, et al. Phytochemical Analysis of the Methanol Extract from Leaves of Cassia fistula L. Journal of Chemical and Pharmaceutical Research. 2016; 8(12): 243-247.
26. Harborne JB, A guide to modern techniques of plant analysis, (Chapman and Hall, London); 1973.
27. Hegnauer R. Chemotaxonomie der Pflanzen, Bikhäuser Verlag, Basel, Suttgart, An overview of the distribution and the systematic importance of plant substance.1973:6:761.
28. Békro YA, Békro JAM, Boua BB, Tra BFH, Ehilé EE. Phytochemical Screening, Antioxidant and Antibacterial activity of Lepidium sativum seeds from Morocco. Rev. Sci. Nat 2007; 4 (2): 217-225.
29. Ronchetti F, Russo G. A new alkaloid from Rauwolfia vomitoria. Phytochem. 1971;10 :1385-1388.
30. Lister E, Wilson P. Measurement of Total Phenolics and ABTS Assay for Antioxidant Activity (Personal communication) Crop Research Institute; Lincoln, New Zealand. 2001.
31. Jia Z, Tang M, Wu J. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 1999; 64: 555–599.
32. Huang B, Ban XQ, He JS, Tong, Tian J, Wang YW, Hepatoprotective and antioxidant activity of ethanolic extracts of edible lotus (Nelumbo nucifera Gaertn.) leaves. Food Chem. 2010; 120: 873–878.
33. Wadhawa G. et al. Antibacterial and antioxidant study of ocimumbasilicumlabiatae (Sweet basil). International, Journal of Advanced Pharmacy Education and Research. 2011; 2: 104-112.
34. Wadhawa G et al. Anti-oxidant effect of stem and leaves of hibiscus esculantuslinn International IJPSR 2011; 2(14): 748-750.
35. Gunalan G, Suresh Kumar M, Sangeetha N. Preliminary Phytochemical Analysis and In Vitro Oxidant Scavenging Activity of Rosemary officinalis. Research J. Pharm. and Tech. 2011; 4(10): 1588-1590.
36. Balamurugan G, Arunkumar MP, Muthusamy P, Anbazhagan S. Preliminary Phytochemical Screening, Free radical Scavenging and Antimicrobial activities of Justicia tranquebariensis Linn. Research J. Pharm. and Tech. 2008; 1(2): 116-118.
37. Elias J, Rajesh MG, Anish NP, Sunny S, Jayan N. Free Radical Scavenging Activity and Phytochemical Profiling of Acalypha indica Linn. Research J. Pharm. and Tech. 2010; 3(4): 1231-1234.
38. Karthik VP, Punnagai, Suresh P, David DC. In Vitro Hydrogen Peroxide Scavenging Activity and Alpha Amylase Inhibitory Activity of Croton tiglium extract. Research J. Pharm. and Tech. 2019; 12(6): 3045-3047. doi: 10.5958/0974-360X.2019.00515.8
39. Vaishnava MM, Tripathi AK and Gupta KR. Constituents of Typhonium flagelliformeroots. Fitoterapia. 1993.
40. Harish R, Shivanandappa T. Antioxidant activity and hepatoprotective potential of Phyllanthus niruri. Food Chem 2006; 95: 180 -185.
41. Katalinic V, Milos M, Kulisic T, Jukic M. Screening of 70 medicinal plant extracts for antioxidant capacity and total phenols. Food Chem. 2006; 94: 550-557.
42. Kim HW, Murakami A, Williams MV, Ohigashi H. Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells. Carcinogenesis 2003; 24: 235-241.
43. Badmanaban R, Prajapati MG, Patel CN, DJ Sen, Panigrah B. Studies on Leaf extracts of drug Punarnava by comparing its Antioxidant potential by Spectrophotometric method. Research J. Pharm. and Tech. 2010; 3(2): 566-569.
44. Kumaran A, Karunakaran RJ. Antioxidant and free radical scavenging activity of an aqueous extract of Coleus aromaticus. Food Chem 2006; 97: 109-114.
45. Sureshkumar CA, Meera R, Devi P, Sathish M, Varadharajan R, Muthumani P. Antinociceptive, Anti-inflammatory activity of Coriander sativum Leaves. Research J. Pharm. and Tech. 2010; 3(3): 744-747.
46. Wadhawa G et al. Antibacterial.antioxidant, antiinflametry study of leaves and bark of Typhonium flagelliforme. Int J Pharma. 2012; 2(1): 401-405.
47. Wadhawa G et al. Antibacterial and antioxidant antiinflametry study of leaves and roots of Delonex regia IJPCS 2013; 1(2): 131-135.
48. Wadhawa G et al. Phytochemical Analysis of the Menthol Extract from leaves of Hemidesmus Indicus. Europian Journal of Biomedical and Pharmaceutical Science. 2016; 3(12): 539-543.