Author(s): Zeyad Safauldeen Abdullahe, Bayader F. Abbas, Athraa Salman ahmed, Lubna F. Mohammed, Hanan Kd. Shaaban, Wessal M. Khamis

Email(s): wessalmetaab@uomustansiriyah.edu.iq , bayaderfaa@uomustansiriyah.edu.iq

DOI: 10.52711/0974-360X.2021.00453   

Address: Zeyad Safauldeen Abdullahe, Bayader F. Abbas, Athraa Salman ahmed, Lubna F. Mohammed, Hanan Kd. Shaaban, Wessal M. Khamis*
Mustansiriyah University, College of Science, Chemistry Department.
*Corresponding Author

Published In:   Volume - 14,      Issue - 5,     Year - 2021


ABSTRACT:
Dentate ligands 2-[(2,3-dimethylphenyl)amino]benzoic acid (Mefenamic acid ) and 2,5-diamino-5-oxopentanoic acid(glutamine) were used as bidentate Lewis base to prepare solid complexes with Molybdenum (V), Tungsten (V)) and Lanthanum(III). The Photo degradation study was achieved for the complexes solutions in methanol. The prepared complexes were characterized by using spectroscopy methods like FTIR, UV-visible, Melting points and flame atomic absorption spectroscopy were calculated for all complexes. Furthermore the molar conductance of 0.001 M solutions in acetonitrile and magnetic susceptibility were performed to elucidate the proposed geometry and structures of prepared complexes. Magnetic susceptibility displayed that complexes had not diamagnetic properties. Photo kinetic study was done for La and Mo Complexes to study the photo sensitivity of prepared complexes. Half time of the complexes` photo reaction were achieved and order of reactions were calculated which appear that photo reaction of LaIII complex was from the first order and constant of reaction was calculated (1.62x10-2) min-1 and half time of reaction was (62.112) min. Also, order reaction of Mo (III) complex was from first order too, the value of constant of reaction was (1.88 min-1) and half time of reaction was (26.6) min. TGA analysis of MoIII was done.


Cite this article:
Zeyad Safauldeen Abdullahe, Bayader F. Abbas, Athraa Salman ahmed, Lubna F. Mohammed, Hanan Kd. Shaaban, Wessal M. KhamisSynthesis, Characterization and Photo Degradation Studies of New Mixed Ligand Transition Metal Complexes of Mefenamic Acid and Glutamine. Research Journal of Pharmacy and Technology. 2021; 14(5):2576-0. doi: 10.52711/0974-360X.2021.00453

Cite(Electronic):
Zeyad Safauldeen Abdullahe, Bayader F. Abbas, Athraa Salman ahmed, Lubna F. Mohammed, Hanan Kd. Shaaban, Wessal M. KhamisSynthesis, Characterization and Photo Degradation Studies of New Mixed Ligand Transition Metal Complexes of Mefenamic Acid and Glutamine. Research Journal of Pharmacy and Technology. 2021; 14(5):2576-0. doi: 10.52711/0974-360X.2021.00453   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-5-37


REFERENCES:
1.    Kawamori T., Rao C.V., Seibert K. and Reddy B.S. Chemopreventive Activity of Celecoxib, a Specific Cyclooxygenase-2 Inhibitor, against Colon Carcinogenesis.1998;Cancer Res.58: 409-412.
2.    Brittain H.G. Analytical Profiles of Drug Substances and Excipients. Academic Press, New York. 2002;: 179-211.
3.    Greenaway F.T., Riviere E., Girerd J.J., Labouze X., Morgant G., Viossat B., Daran J.C., Roch M. N. Arveiller and Dung H. J. Inorg. Biochem.1999; 76: 19-27.
4.    Dutta S., Padhye S. and McKee V. Inorg. Chem. Commun.2004; 7 : 1071-1074.
5.    Moncol J., Kalinakova B., Svorec J., Kleinova M., Koman M., Hudecova D., Melnik M., Mazur M. and Valko M. Inorg. Chim.Acta. 2004; 357: 3211-3222.
6.    Mohammad Edrissi, Nima Razzaghi Asl and Behrooz, Madjidi. Interaction of Mefenamic Acid with Cobalt(II) Ions in Aqueous Media: Evaluation via Classic and Response Surface Methods. Turk J Chem. 2008; 32: 505-519.
7.    M. Khamis Wessal, F. Abbas Bayader, H. Abd-Al-Sada Shayamaa, Taha Mohammed Mustafa, A. Sultan Alaa and M. Khamis Nedhal. Preparation, Investigation and Enzymatic Activity of Mixed Iigand Complexes of Mefenamic Acid and Phenyl Alanine with some Transition Metal. Journal of Engineering and Applied Sciences.2019; 14 (3): 734-743.
8.    Chap.16,Amino Acid,proteinsandEnzymes,www.bakersfieldcollege.edu/deharvey/ PPT/ CH em%2011%20Tmberler%20powerpoint/chem%2011.chap.chap.%2016.12.10-11dch.pdf.
9.    Amino acids , Peptides and Protein, chapter 5, Spider Silk; A Bio Steel Protein.
10.    H. Abdel-Rahmana Laila, M. Abu-Diefa Ahmed, M. Ismaila Nabawia and Ismaela Mohamed . Synthesis, characterization, and biological activity of new mixed ligand transition metal complexes of glutamine, glutaric, and glutamic acid with nitrogen based ligands. Inorganic and Nano-Metal Chemistry. 2017;47(3):467–480.
11.    Nelson D.L. and Cox M. M. Lehninger .Principles of Biochemistry.3rded;Worth New York. 2000.
12.    Bergström J, Fürst P, Norée LO, Vinnars E.`` The intracellular free amino acid concentration in human muscle tissue. J. of Appl. Physiology.1974;36:693-697.
13.    H. Al-Zaidi Basim, H. Ismail Ahmed, N. Naseaf Ali and Khamis Wessal. Preparation, Characterization and Biological Activity of New Tridentate Imine-Oxime Ligand(H2L) and Its Metal Complexes. Asian Journal of Chemistry.2018; 30 (5): 1157-1164.
14.    M. Khamis Wessal, S.H. Mohammed Suhair, H. Abdullah Amer, Gd. Sha`aban Hanan, H. Abdul Sada Shaemmaa, Azer Daher Gwan. Enzymatic Activity and Photo-Kinetic Study of Cr(III), Mn(II), Co(II), Ni(II) and Cu(II) Complexes with Tetradentate Schiff Base Ligand. International Journal of Engineering and Technology.2018; Vol.7, No 4.37.
15.    House J. Principles of Chemical Kinetics, Academic Press. New York, NY, USA, 2007, V. Patel, Ed., Chemical Kinetics, In Tech, Rijeka, Croatia.2012.
16.    Y. Maeda and R. Okawara. Vibrational Spectra of Organometallics: Theoretical and Experimental Data. J.Organomet.Chem.1967;10, p. 247.
17.    Ramzana S., Saleemb S., Mirzab B., Alia S., Ahmedc F. and Shahzadia S. Synthesis, Characterization, and Biological Activity of Transition Metals Complexes with Mefenamic Acid (NSAIDs)1. Russian Journal of General Chemistry, Pleiades Publishing, Ltd., 2015; 85, No. 7:1745–1751.
18.    F. Abbas Bayader. Structural Study and Antimicrobial Evaluation of Some Transition Metal Complexes with Pyrazole Base Ligand 5-{[(E)-(1,4-diphenyl-1H-pyrazol-3-yl) methylidene]amino}-1,3-thiazol-4-ol. Asian J. Research Chem. 2016;9(1):6-12.
19.    M.C Deleuze; G. Moarbess, S. Khier, N. David, P.S. Gayraud, F. Bressolle, Bonnet F., Pingue P.A. Newimidazo[1,2-a]quinoxaline derivatives: Synthesis and in itro activity against human melanoma.Eur.J.Med.Chem.2009;44:3406–3411.
20.    Krushna C.H., Mahapatra C.M. and K.C. Dash. 4,5 and 6–coordinate complexes of CuII with substituted imidazoles. Inorg. Nucl. Chem.1977; 39, 1253.
21.    A. B.P. Lever. Inorganic Electronic Spectroscopy. New York.1968;274-283.
22.    Benelli C. and Gatteschi D. Chemical Reviews. 2002;102, 2369.
23.    Greenwood N. N. and Earnshaw A. Chemistry of the elements. Oxford: Butterworth-Heinemann Elsevier.2012.
24.    Hu J. M., Zhang J. Q. and Cao C. N. Thermochimica Acta.2003; 403, 257.
25.    Cifelli M., Domenici V. and Veracini C.A. Current Opinion in Colloid and Interface Science. 2013; 18, 190.

Recomonded Articles:

Author(s): Roushan Mubarak, Shaden Haddad, Outhman Hamdan

DOI: 10.5958/0974-360X.2016.00022.6         Access: Open Access Read More

Author(s): Saurabh Bharadwaj, U.V.S. Teotia, Kishan Singh, Rajib Sharma, Yogendra Singh

DOI: Not Available         Access: Open Access Read More

Author(s): Abdullahi Rabiu Abubakar, Nordin Bin Simbak, Mainul Haque

DOI: Not Available         Access: Open Access Read More

Author(s): Chinedu Fredrick Anowi, Nnabuife Chinedu Cardinal, A.F. Onyegbule, L.N. Anowi

DOI: Not Available         Access: Open Access Read More

Author(s): Arunava Das, M. Bharath, M. Jeevanantham, S. Manoj Kumar, R. P. Thanarithanika J.Bindhu

DOI: 10.5958/0974-360X.2018.00752.7         Access: Open Access Read More

Author(s): Asri Rachmadi, Diana Lyrawati, Adeltrudis Adelsa Danimayostu

DOI: 10.5958/0974-360X.2017.00444.9         Access: Open Access Read More

Author(s): Imad Hadi Hameed, Maria Rosario Calixto Cotos, Mohammed Yahya Hadi

DOI: 10.5958/0974-360X.2017.00739.9         Access: Open Access Read More

Author(s): Mohammed Khanji, Ghoufran Kawas, Mohammad Haroun, Mouhammad Abu Rasheed, Amir Alhaj Sakur

DOI: 10.5958/0974-360X.2020.00396.0         Access: Open Access Read More

Author(s): G. Bhuvaneshwari, . A. S. Shameembanu, M. Kalyani

DOI: 10.5958/0974-360X.2018.00244.5         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags