Author(s): Cat Thien Phuc, Doan Thi Thanh Vinh, Truong Khoa My, Tran Thi Thu Hien, Nguyen Anh Dung, Tran Thi Minh Thu, Tu Hoang Khue Nguyen

Email(s): nhktu@hcmiu.edu.vn

DOI: 10.52711/0974-360X.2021.00387   

Address: Cat Thien Phuc1,2, Doan Thi Thanh Vinh1,2, Truong Khoa My1,2, Tran Thi Thu Hien1,2, Nguyen Anh Dung1,2,3, Tran Thi Minh Thu1,2, Tu Hoang Khue Nguyen1,2*
1School of Biotechnology, International University, Vietnam.
2Vietnam National University – Ho Chi Minh City, Vietnam.
3Faculty of Nautral Sciences, Thu Dau Mot University, Vietnam.
*Corresponding Author

Published In:   Volume - 14,      Issue - 4,     Year - 2021


ABSTRACT:
Lactic acid bacteria play a vital role in biosynthesis of ? -aminobutyric acid (GABA) in the presence of glutamic acid - major substrate for the process. In recent study, Lactobacillus fermentum A01 (L. fermentum A01) isolated from various sources in Vietnam were screened for bacteria strains with high efficiency in GABA formation. L. fermentum was cultured in MRS broth containing 25 mg/mL monosodium glutamate (MSG), at pH of 6.5 and incubated at the optimal conditions (37ºC, for 24, 48, 72 h). After extraction and thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC) analysis, L. fermentum A01 showed the GABA yield about 1.34 mg/g in dried supernatant, suggesting L. fermentum A01 to be a promising GABA producer for food and pharmaceutical applications.


Cite this article:
Cat Thien Phuc, Doan Thi Thanh Vinh, Truong Khoa My, Tran Thi Thu Hien, Nguyen Anh Dung, Tran Thi Minh Thu, Tu Hoang Khue Nguyen. Study on conditions for Gama buryric acid (GABA) production in Lactobacillus fermentum A01 isolated from human. Research Journal of Pharmacy and Technology. 2021; 14(4):2188-0. doi: 10.52711/0974-360X.2021.00387

Cite(Electronic):
Cat Thien Phuc, Doan Thi Thanh Vinh, Truong Khoa My, Tran Thi Thu Hien, Nguyen Anh Dung, Tran Thi Minh Thu, Tu Hoang Khue Nguyen. Study on conditions for Gama buryric acid (GABA) production in Lactobacillus fermentum A01 isolated from human. Research Journal of Pharmacy and Technology. 2021; 14(4):2188-0. doi: 10.52711/0974-360X.2021.00387   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-4-63


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