ABSTRACT:
Aqueous extract of bark of Kigelia pinnata was used as reducing source for the biological green synthesis of AgNPs. The synthesized particles were characterized by UV-Visible spectrum, XRD, SEM, dynamic light scattering (DLS). The anti-fungal activity of AgNPs was evaluated against Aspergillus niger (MTCC:281), Aspergillus flavus (MTCC:277) and Candida albicans (MTCC:227) by agar diffusion method. Particle size of AgNPs was measured as 76.4nm ± 6.3nm and Zeta potential was stable at -43.2mV using DLS analysis. SEM analysis measured the size of AgNPs as ~75nm. XRD analysis confirmed that the synthesized NPs were silver (Ag), based on the JCPDS entry 85-1355 and it is crystalline in nature. The size of the crystal was calculated as 10nm using the Scherrer formula. The AgNPs demonstrated significant anti-fungal activity against C. albicans (MIC:15.6µg/ml), A. niger (MIC:62.4µg/ml) and A. flavus (MIC:31.2µg/ml). These results confirm that AgNPs synthesized using K. pinnata barks could be used as potential antifungal agent against fungal pathogens.
Cite this article:
Lokesh Ravi, Krishnan Kannabiran. Antifungal potential of green synthesized silver nanoparticles (AgNPS) from the stem bark extract of Kigelia pinnata. Research Journal of Pharmacy and Technology. 2021; 14(4):1842-6. doi: 10.52711/0974-360X.2021.00326
Cite(Electronic):
Lokesh Ravi, Krishnan Kannabiran. Antifungal potential of green synthesized silver nanoparticles (AgNPS) from the stem bark extract of Kigelia pinnata. Research Journal of Pharmacy and Technology. 2021; 14(4):1842-6. doi: 10.52711/0974-360X.2021.00326 Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-4-2
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