ABSTRACT:
Present study was to investigate antidiabetic and anti-inflammatory activity ethanol extract of leaves of plant Barleria gibsoni Dalz. in-vitro. As per phytochemical investigation the extracts show presence of Flavanoids, tannins and saponins. The ethanolic leaves extract of Barleria gibsoni Dalz with a dose of 10, 20, 30, 40 and 50 µg/ml, was taken for the activity and compared with the standard drug. Egg albumin denaturation and bovine serum fraction model was taken for activity and compared with Aspirin 10-50µg/ml. The samples at concentration (20, 40, 60, 80, 100µg/ml) were studied for antidiabetic effect on glucose transport across yeast cells and a- Amylase inhibition. The ethanol extract of leaves showed that significant result in both anti-inflammatory as well as antidiabetic models. However, these effects need to be confirmed using in vivo models and clinical trials for its effective utilization as therapeutic agents.
Cite this article:
Firoj A. Tamboli, Harinath N. More. In vitro screening of Anti-diabetic activity and Anti-inflammatory activity of leaves extract of Barleria gibsoni Dalz. Research J. Pharm. and Tech 2021; 14(3):1289-1292. doi: 10.5958/0974-360X.2021.00228.6
Cite(Electronic):
Firoj A. Tamboli, Harinath N. More. In vitro screening of Anti-diabetic activity and Anti-inflammatory activity of leaves extract of Barleria gibsoni Dalz. Research J. Pharm. and Tech 2021; 14(3):1289-1292. doi: 10.5958/0974-360X.2021.00228.6 Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-3-16
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