Author(s): Shashikant Sudarshan Upadhye, Srinath Balkundhi, Vishwajeet Sampatrao Ghorpade, Shirishkumar Damodar Ambavade, Sujit Vitthal Abhang, Safina Ismail Mulla, Priya Abhishek Patil

Email(s): ssupadhye7@gmail.com

DOI: 10.5958/0974-360X.2021.00319.X   

Address: Shashikant Sudarshan Upadhye1*, Dr. Srinath Balkundhi2, Dr. Vishwajeet Sampatrao Ghorpade3, Dr. Shirishkumar Damodar Ambavade4, Mr. Sujit Vitthal Abhang1, Ms. Safina Ismail Mulla1, Mrs. Priya Abhishek Patil1
1PhD Research Scholar, School of Pharmaceutical Sciences, Sanjay Ghodawat University, Atigre, Kolhapur: 416118, Maharashtra.
2Associate Professor, School of Pharmaceutical Sciences, Sanjay Ghodawat University, Atigre, Kolhapur: 416118, Maharashtra.
3Assistant Professor, School of Pharmaceutical Sciences, Sanjay Ghodawat University, Atigre, Kolhapur: 416118, Maharashtra.
4Professor and Principal, School of Pharmaceutical Sciences, Sanjay Ghodawat University, Atigre, Kolhapur: 416118, Maharashtra.
*Corresponding Author

Published In:   Volume - 14,      Issue - 3,     Year - 2021


ABSTRACT:
The nanosponge is the novel and emerging technology which plays a vital role in targeting drug delivery in the controlled manner. The nanosponges are tiny sponges having size of about a virus and it can easily penetrate through the skin. The tiny sponges circulate around the body until they reach to the specific target site and stick on the surface and start to release the drug in controlled manner. It releases the drug at specific site instead of circulating overall body it is more effective for targeted drug delivery system as they enhance solubility, bioavailability and reduces side effects. Nanosponges prevent drug and protein degradation. Both hydrophilic and lipophilic drugs are incorporated in Nanosponge. In this review mechanism, method of preparation, evaluation, stabilization and applications of nanosponges are discussed.


Cite this article:
Shashikant Sudarshan Upadhye, Srinath Balkundhi, Vishwajeet Sampatrao Ghorpade, Shirishkumar Damodar Ambavade, Sujit Vitthal Abhang, Safina Ismail Mulla, Priya Abhishek Patil. Nanosponges: An Innovative Approach for Targeted Drug Delivery System. Research J. Pharm. and Tech 2021; 14(3):1797-1804. doi: 10.5958/0974-360X.2021.00319.X


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