Author(s): Mohammed Khaleel Saeed, Saja Ayad Najim, Noor Sabah Salman, Saad Saleem Abdulbaqi, Farah Ghassan Jawad

Email(s): mohkh66@gmail.com

DOI: 10.5958/0974-360X.2021.00111.6   

Address: Mohammed Khaleel Saeed*, Saja Ayad Najim, Noor Sabah Salman, Saad Saleem Abdulbaqi, Farah Ghassan Jawad
Directorate of Materials Research, Ministry of Science and Technology, Baghdad, Iraq.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2021


ABSTRACT:
Staphylococcus aureus infection is a frequent cause of human sepsis, it is an infection linked with high mortality and without specific intervention. When they exist in human or animal plasma, staphylococci are known to agglutinate, however the bacterial agents responsible for agglutination and their possible contribution to disease pathogenesis have not yet been revealed. There are various edible plants possesses different pharmacological activities one of them Raisins, which contained Protocatechuic acid (PCA), a simple phenolic acid. High performance liquid chromatography (HPLC) was used to determine (PCA) in the phenolic compounds. The aim of broth and agar dilution methods is to determine the lowest concentration of the assayed antimicrobial agent (minimal inhibitory concentration, MIC) that, under defined test conditions, inhibits the visible growth of the bacterium being investigated concentration was (125, 312, 625, 1250, 2500) µg/ml. The highest inhibitory effect observed was (Livoflaxcin, Ciproflaxacin, Tigacyclin, Nitrofurantation, Vancomycin). Thus revealing the potential of these extracts as possible alternatives for use in the food and/or pharmaceutical industries. The aim of this study was to evaluate the antibacterial activity of Raisin extract containing protocatechuic acid against Gram-positive bacterial strains (Staphylococcus aureus), isolated from clinical samples.


Cite this article:
Mohammed Khaleel Saeed, Saja Ayad Najim, Noor Sabah Salman, Saad Saleem Abdulbaqi, Farah Ghassan Jawad. Biological activity against Staphylococcus aureus of Isolated from raisins containing protocatechuic acid. Research J. Pharm. and Tech. 2021; 14(2):623-627. doi: 10.5958/0974-360X.2021.00111.6


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