Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Development and Characterization of Corticosteroid loaded Lipid carrier system for Psoriasis

Author(s): Krishna Yadav, Deependra Singh, Manju Rawat Singh

Email(s): manjursu@gmail.com

DOI: 10.5958/0974-360X.2021.00172.4   

Address: Krishna Yadav, Deependra Singh, Manju Rawat Singh*
University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, 492010, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2021

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ABSTRACT:
Psoriasis is a highly complex autoimmune disease of skin with keratinocytes that differentiate abnormally. Because of the inaccessibility of the adequate delivery system, a very favored treatment approaches contemplating topical treatment with current delivery approach are unreliable in targeting disease symptoms. The current work involved the development and characterization of Triamcinolone acetonide loaded solid lipid nanoparticles (TAC-SLNs) and their invitro characterization. The findings revealed that SLNs would substantially increase TA drug permeation across the skin, limiting them to dermis epidermis and helping to achieve the full clinical value of medications. It was also able to sustain the release of drug from lipid carrier. The outcomes of this research concluded that SLNs may efficiently deliver corticosteroids for the efficient treatment of psoriasis.


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Cite this article:
Krishna Yadav, Deependra Singh, Manju Rawat Singh. Development and Characterization of Corticosteroid loaded Lipid carrier system for Psoriasis. Research J. Pharm. and Tech. 2021; 14(2):966-970. doi: 10.5958/0974-360X.2021.00172.4


REFERENCES:
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DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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