Author(s): Amer Th. Al-Taee, Aws Z. Al-Hafidh

Email(s): amerthanon@yahoo.com , aws.alhafidh@gmail.com

DOI: 10.52711/0974-360X.2021.01131   

Address: Amer Th. Al-Taee1*, Aws Z. Al-Hafidh2
1Department of Chemistry, College of Sciences, Mosul University, Mosul, Iraq.
2Chemical Industries, Technical Institute, Mosul, Northern Technical University, Mosul, Iraq.
*Corresponding Author

Published In:   Volume - 14,      Issue - 12,     Year - 2021


ABSTRACT:
A square wave voltammetric technique coupled with three electrode detection system consist of hanging mercury drop electrode (HMDE) as working electrode, 1mm platinum wire as an auxiliary electrode (Pt-wire) and silver/silver chloride saturated potassium chloride (Ag/AgCl.sat.KCl) as reference electrode was used to determine the chlorpropamide indirectly through its interaction with valsartan, chlorpropamide gives no reduction peaks in the studied range. The effect of pH and the stability of the measurement were examined calibrations curve of chlorpropamide was constructed and the relation between current and concentration of chlorpropamide was linear with R2 value = 0.9944. The limit of detection for chlorpropamide was 4.89 x 10-9 M through its interaction with valsartan.


Cite this article:
Amer Th. Al-Taee, Aws Z. Al-Hafidh. Indirect Electrochemical Determination of Chlorpropamide Through Its Interaction with Valsartan Using Square Wave Voltammetry. Research Journal of Pharmacy and Technology. 2021; 14(12):6541-4. doi: 10.52711/0974-360X.2021.01131

Cite(Electronic):
Amer Th. Al-Taee, Aws Z. Al-Hafidh. Indirect Electrochemical Determination of Chlorpropamide Through Its Interaction with Valsartan Using Square Wave Voltammetry. Research Journal of Pharmacy and Technology. 2021; 14(12):6541-4. doi: 10.52711/0974-360X.2021.01131   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-12-61


REFERENCES:
1.    Foster RW. Basic Pharmacology. Published by Butterworth Heinemann Ltd., London. 1991; 3rd ed: p. 186.
2.    Dinnendahl V, Fricke U. Arzneistoff-Profile. Govi Pharmazeutischer Verlag, Eschborn, Germany. 2010; 4(23ed): ISBN 978-3-7741-9846-3.
3.    Odunola MTB, Enemali IS, Garba M, Obodozie OO. Rapid High Performance Liquid Chromatographic Determination of Chlorpropamide in Human Plasma. African Journal of Biotechnology. 2007; 6(12): 1378–1381.
4.    Kishikawa N, Hammad FS, Ohyama K, Kubo K, Mabrouk MM, Nakashima K, Kuroda N. HPLC Determination of Chlorpropamide in Human Serum by Fluorogenicderivatization Based on The Suzuki Coupling Reaction with Phenylboronic Acid. Chromatographia. 2013; 76(11-12): 703-706.
5.    Basavaiah K, Rajendraprasad N. High Performance Liquid Chromatographic Assay of Chlorpropamide, Stability Study and its Application to Pharmaceuticals and Urine Analysis. Austin Journal of Analytical and Pharmaceutical Chemistry. 2017; 4(1): 1082
6.    The British Pharmacopeia. Vol. III. Her Majesty Stationary Office, London. 2008: p. 2530.
7.    Mbah CJ, Okorie NH. Spectrophotometric Determination of Chlorpropamide in Bulk and Dosage Form by Complexation with Chloranilic Acid. Journal of Scientific Research. 2011; 3(1): 207-212.
8.    El-Bardicy MG, El-Khateeb SZ, Assad HN, Ahmed AS. Mercurimetric Determination of Chlorpropamide by Back Titration. Indian Journal of Pharmaceutical Sciences. 1988; 50(3): 171-172.
9.    Nourrudin AW, Abdelwahab NS, El-Zeiny BA, Tohamy SI. Stability Indicating TLC-Densitometric Method for Determination of Chlorpropamide. Journal of Liquid Chromatography and Related Technology. 2013; 36(11): 1575-1585.
10.    Anna G, Hanna H, Anna B, Dorota K. Normal- and Reversed-Phase Thinlayer Chromatography of Seven Oral Antidiabetic Agents. Journal of Planar Chromatography- Modern TLC. 2003; 16(4): 271-275.
11.    Khalid S, Khawla S. Gas Chromatographic Method for Determination of Tolbutamide and Chlorpropamide. Journal of Pharmaceutical Sciences. 1970; 59(6): 782-784.
12.    Nasierowska Z, Suffczynski J, Szyszko E, Taton J, Kolinski P, Czech A, Wojterska J. Modification of The Gas Chromatographic Method for Blood Chlorpropamide Determination and Evaluation of Its Use for Clinical and Pharmacological Purposes. Polish Journal of Pharmacology and Pharmacy. 1983; 35(5): 405-415.
13.    El-Sayed MA, Agarwal SP. Spectrophotometric Determination of Atropine, Pilocarpine and Strychnine with Chloranilic Acid. Talanta. 1982; 29(6): 535-537.
14.    Chitlange SS, Bagri K, Sakarkar DM. Stability Indicating RP- HPLC Method for Simultaneous Estimation of Valsartan and Amlodipine in Capsule Formulation. Asian Journal of Research in Chemistry. 2008; 1(1): 15-18.
15.    Gawai MN, Aher SS, Saudager RB. New UV – Spectrophotometric Method Development and Validation of Valsartan in Bulk and Pharmaceutical Dosage Forms. Asian Journal of Research in Chemistry. 2016; 9(9): 441-444.
16.    Yogeshwar RM, Ramesh V, Kista RCh, Venugopal N, Saravanan G, Suresh Y, Suryanarayana M, Debashish D, Raju B. Low-Level Determination of Residual 4-Bromo Methyl-2'-Cyanobiphenyl in Valsartan by Liquid Chromatography-Mass Spectrometry. Asian Journal of Research in Chemistry. 2010; 3(2): 407-410.
17.    Shinde SR, Bhoir SI, Pawar NS, Bhagwat AM. Quantitation of Valsartan in Human Plasma by High Performance Liquid Chromatography with Fluorescence Detection and its Application to Bioequivalence Study. Research Journal of Pharmacy and Technology. 2009; 2(3): 487-490.
18.    Singh SM, Topagi KS, Damle MC. A Validated High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Nebivolol Hydrochloride and Valsartan in Pharmaceutical Dosage Form. Research Journal of Pharmacy and Technology. 2009; 2 (4): 746-749.
19.    Vaidya N, Choure R. Electrochemical Analysis of Fatty Acids Obtained from the Natural Resource Seed of Perilla frutescens. Asian Journal of Research in Chemistry. 2011; 4(5): 705-707.
20.    Kumar PCR, Naidu GRK, Sridevi C, Reddy CS. Electrochemical Reduction Behaviour of Guanethidine. Asian Journal of Research in Chemistry. 2011; 4(12): 1928-1929.
21.    Ramadan AA, Mandil H, Abu-Saleh R. Electrochemical Behavior and Differential Pulse Polarographic Determination of Flucloxacillin in Pure and Pharmaceutical Dosage Forms Using Dropping Mercury Electrode. Research Journal of Pharmacy and Technology. 2019; 11(8): 3313-3319.
22.    Ramadan AA, Mandil H, Ashram N. Differential Pulse Polarographic Behavior and Determination of Simvastatin in Pure and Pharmaceutical Dosage Forms Using Dropping Mercury Electrode. Research Journal of Pharmacy and Technology. 2018; 11(7): 2888-2894.
23.    Singh J, Sharma SK. Electrochemical behaviour of In(III) with Isoleucine in aqueous and non-aqueous media at Dropping Mercury Electrode. Asian Journal of Research in Chemistry. 2018; 11(2): 391-394.
24.    Mohapatra SS, Kafle A, Reddy I, Sarma J. Drug Interactions with Antibiotics. International Journal of Chemical Studies. 2018; 6(2): 2120-2122.
25.    Monago CC, Gozie GC, Joshua PE. Antidiabetic and Antilipidemic Effects of Alkaloidal Extract of Emilia sonchifolia in Rat. Research Journal of Science and Technology. 2010; 2(3): 51-56.
26.    Bhavimani G, Nitin M. Pharmacological Studies on Drug-Drug Interactions between Antidiabetic Drug (Glibenclamide) and Selective Anti-HIV Drug (Lamivudine) in Rats and Rabbits. Research Journal of Pharmacology and Pharmacodynamics. 2017; 9(3): 117-121
27.    Alhafidh AZ, Altaee AT. Electrochemical Behavior of Valsartan, Glibenclamide and Their Interaction with Each Other Using Square Wave Voltammetry. Rafidain journal of science. 2019; 28(2): 64-75.
28.    Jalali F, Dorraji PS. Electrochemical and Spectroscopic Studies of The Interaction Between the Neuroleptic Drug, Gabapentin, and DNA. Journal of Pharmaceutical and Biomedical Analysis. 2012; 70: 598-601.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags


Not Available