Author(s): Suhani Sumalatha, Gururaj Tantri, Jessica Shreshta, Ashwija Shetty, Vanishree S Nayak, Sushma Prabhath

Email(s): sushma.rk@manipal.edu

DOI: 10.52711/0974-360X.2021.01122   

Address: Suhani Sumalatha1, Gururaj Tantri2, Jessica Shreshta1, Ashwija Shetty1, Vanishree S Nayak1, Sushma Prabhath1*
1Department of Anatomy, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India – 576104.
2Department of Shalya Tantra, Muniyal College of Ayurveda, Manipal, Karnataka, India- 576104.
*Corresponding Author

Published In:   Volume - 14,      Issue - 12,     Year - 2021


ABSTRACT:
Ayurveda, an ancient Indian medicinal system, is highly regarded as complementary and alternative medicine in recent years. However, there are reports to show the toxic effects of specific Ayurvedic preparations, which use metals as an ingredient in them. One such medicine is 'Ekangaveera Rasa' This herbo-minero-metallic preparation is used to treat the pain of neurological origin. Therefore, the present study aimed to evaluate the possible alteration caused by Ekangaveera Rasa on the brain, liver, and kidneys by histological, biochemical, and behavioral analysis. For this evaluation, Wistar rats were divided into four groups: Group 1- normal control; group 2, 3 and 4 were treated with Ekangaveera Rasa at doses of 120, 240 and 600 mg/kg bodyweight for 30 days. Behavioral parameters were assessed on the 15th and 30th day by using the passive avoidance test. At the end of the treatment period, blood was collected and subjected to the basophilic stripling and biochemical analysis. Tissues were processed for histopathological evaluation. The histopathological, biochemical, and behavioral analysis did not show any harmful effect, thereby rendering Ekangaveera Rasa nontoxic and further glorifying the healing benefits of Ayurveda.


Cite this article:
Suhani Sumalatha, Gururaj Tantri, Jessica Shreshta, Ashwija Shetty, Vanishree S Nayak, Sushma Prabhath. Evaluation of an Ayurvedic preparation-‘Ekangaveera Rasa' for possible metal toxicity: Behavioral, Biochemical and Histopathological Analysis. Research Journal of Pharmacy and Technology. 2021; 14(12):6491-5. doi: 10.52711/0974-360X.2021.01122

Cite(Electronic):
Suhani Sumalatha, Gururaj Tantri, Jessica Shreshta, Ashwija Shetty, Vanishree S Nayak, Sushma Prabhath. Evaluation of an Ayurvedic preparation-‘Ekangaveera Rasa' for possible metal toxicity: Behavioral, Biochemical and Histopathological Analysis. Research Journal of Pharmacy and Technology. 2021; 14(12):6491-5. doi: 10.52711/0974-360X.2021.01122   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-12-52


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