Author(s): Fitriyanti Jumaetri Sami, Nunuk Hariani Soekamto, Tatsufumi Okino, Firdaus, Jalifah latip

Email(s): nunukhariani@unhas.ac.id

DOI: 10.52711/0974-360X.2021.01074   

Address: Fitriyanti Jumaetri Sami1,2*, Nunuk Hariani Soekamto1, Tatsufumi Okino3, Firdaus1, Jalifah latip4
1Department of Chemistry, Hasanuddin University, Indonesia.
2Sekolah Tinggi Ilmu Farmasi Makassar, Indonesia.
3Faculty of Environmental Earth Science, Hokkaido University, Japan.
4School of Chemical Sciences and Food Technology, Universiti Kebangsaan Malaysia, Selangor.
*Corresponding Author

Published In:   Volume - 14,      Issue - 12,     Year - 2021


ABSTRACT:
Isolation and characterization of quercetin flavonoid compound from Dutungan Island, South Sulawesi Province, Indonesia has been successfully done from ethyl acetate extract. Extraction method used maceration, isolation used chromatography, anticancer activity with MTT method and antioxidant test used DPPH radical. Structure was discussed with the FT-IR, NMR spectrophotometer and compared with the literature. Total flavonoids from ethyl acetate extract were 4.8 mgEQ/g, IC50 value of antioxidant activity was 4.23 µg/ml using the DPPH method (2,2-diphenyl-1-picrylhydrazyl), and anticancer activity of H460 cells IC50 value was 10.95 µg/ml. The quercetin compound is potential as an anticancer and was first report in the T. decurrens Bory species.


Cite this article:
Fitriyanti Jumaetri Sami, Nunuk Hariani Soekamto, Tatsufumi Okino, Firdaus, Jalifah latip. A Flavonoid compound of Turbinaria decurrens Bory with The Potential Antioxidant and Anticancer Activity. Research Journal of Pharmacy and Technology. 2021; 14(12):6207-0. doi: 10.52711/0974-360X.2021.01074

Cite(Electronic):
Fitriyanti Jumaetri Sami, Nunuk Hariani Soekamto, Tatsufumi Okino, Firdaus, Jalifah latip. A Flavonoid compound of Turbinaria decurrens Bory with The Potential Antioxidant and Anticancer Activity. Research Journal of Pharmacy and Technology. 2021; 14(12):6207-0. doi: 10.52711/0974-360X.2021.01074   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-12-4


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