Author(s):
P. Ezhilarasan, S. Sivakrishnan, S.Vigil Anbiah
Email(s):
sivacdm82@gmail.com
DOI:
10.52711/0974-360X.2021.01024 
Address:
P. Ezhilarasan1, S. Sivakrishnan2*, S.Vigil Anbiah3
1M.Pharm (Pharmacology), Department of Pharmacy, FEAT, Annamalai University, Annamalai Nagar-608002, Tamilnadu, India.
2Assistant Professor, Department of Pharmacy, FEAT, Annamalai University, Annamalai Nagar-608002, Tamilnadu, India.
3Associate Professor and Head I/C, Central Animal House, Rajah Muthiah Medical College, Annamalai University, Annamalai Nagar-608002, Tamilnadu, India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 11,
Year - 2021
ABSTRACT:
Bioactive chemicals of plant source are phytochemicals (secondary metabolites). They are synthesized naturally in all segments of the plant. Caesalpinia bonducella used for psoriasis care by traditional Siddha physicians in the Malabar regions and is also used in Pakistan's traditional medicine scheme. Tree bark has been identified as a purgative and is recommended for the treatment of disorders of the kapha and vata, gynaecological disorders, skin infections, bowel problems, abdominal distension, piles, ulcers. This study is concerned with the phytoconstituents assessment of the ethanolic extract of Caesalpinia bonducella (EECB) leaves. Method: Using Soxhlet apparatus, coarse powder of Caesalpinia bonducella leaves was extracted with ethanol by hot percolation. For 24 hours, the extraction has been worked out. The solvent was extracted out for acquiring a concentrated extract following extraction. The condensed extract was then vacuum dried and the dry extract was processed for specific bioactive compounds investigation in an air tight container. The existence of alkaloids, carbohydrates, proteins & amino acids, hormones, phenols, tannins, flavonoids, glycosides and saponins was revealed in EECB.
Cite this article:
P. Ezhilarasan, S. Sivakrishnan, S.Vigil Anbiah. Phytochemical analysis of ethanolic extract of leaves of Caesalpinia bonducella. Research Journal of Pharmacy and Technology. 2021; 14(11):5891-4. doi: 10.52711/0974-360X.2021.01024
Cite(Electronic):
P. Ezhilarasan, S. Sivakrishnan, S.Vigil Anbiah. Phytochemical analysis of ethanolic extract of leaves of Caesalpinia bonducella. Research Journal of Pharmacy and Technology. 2021; 14(11):5891-4. doi: 10.52711/0974-360X.2021.01024 Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-11-50
REFERENCES:
1. Lalitha T.P and Jayanthi P. “Preliminary studies on phytochemicals and antimicrobial activity of solvent extracts of Eichhornia crassipes (Mart.) Solms,” Asian Journal of Plant Science & Research. 2012; 2(2):115–122.
2. Govindarajan R, Vijayakumar M, and Pushpangadan P. “Antioxidant approach to disease management and the role of “Rasayana” herbs of Ayurveda,” Journal of Ethnopharmacology. 2005; 99(2): 165–178.
3. Dibyajyoti Saha, Swati Paul. Pharmacognostic Studies of Aerial Part of Methanolic Extract of Alpinia conchigera Griff, Asian Journal of Pharmaceutical Analysis. 2012; 2(2):46-48)
4. A. Thenmozhi, U.S Mahadeva Rao. Secondary Metabolite screening, Bioactive compound extraction, and Disrupting Mitotic Activity of Wild Cabbage [Brassicaceae] towards Cancer Management, Asian Journal of Pharmaceutical Research. 2012; 2(1):19-31.
5. Harborne A. Phytochemical methods a guide to modern techniques of plant analysis. Springer science & business media. 1998.
6. Chinedu Fred Anowi, Uyai Umanah, A.U. Emezie, AU Utoh-Nedosa. Anti-diarrhoeal, antispasmodic and phytochemical properties of ethanol extract of the leaves of Ficus exasperate, Asian Journal of Research in Pharmaceutical Sciences. 2012; 2(1):26-32.
7. Tusharkanti Mandal, Jitendra Bhosale, GajendraRao, Madan Mohan Padhi, Rajesh Dabur. Antimicrobial Activities of Gray Nickerbean (Caesalpinia bonduc Linn.). Nuts and Seeds in Health and Disease Prevention, Academic Press. 2011; 67:561-567.
8. Dayanand M. Kannur Antidiabetic and Antihyperlipidemic Activity of Bonducella (Caesalpinia bonducella) Seeds. Nuts and Seeds in Health and Disease Prevention. Academic Press. 2011; 28:237-244.
9. Archana P, Tandan SK, Chandra S, Lal J. Antipyretic and Analgesic Activities of Caesalpinia bonducella seed kernel extract. Journal of Phytotherapy Research. 2005; 19(5):376-381.
10. Gupta, M, Mazumder, U.K., Kumar, R.S., Sivakumar, T., Vamsi, M.L. Antitumor Activity and Antioxidant Status of Caesalpinia bonducella against Ehrlich Ascites Carcinoma in Swiss albino mice. Journal of Pharmacological Sciences. 2004; 94(2):177- 184.
11. B. Meher, T. Satapathy, A.K .Sahu, K .K Ahirwar, P D Kashinath, N P Jain. Screening of Methanolic Extract of Euphorbia hirta linn for Antiinflammatory Activity in Experimental Animals, Research Journal of Pharmacy and Technology. 2012; 5(1):38-40.
12. Tarasankar Maity, Ayaz Ahmad, Nilanjan Pahari, Subarna Ganguli. A Review on Hepatoprotective herbs for treatment of various liver Disorders, Research Journal of Pharmacy and Technology. 2012; 5(5):602-607.
13. Gadakh M, Jadhav R, Vikhe D. Biological Potential of Caesalpinia bonducella Seeds- A Review, Journal of Drug Delivery & Therapeutics.2020; 10(3-s):308-310.
14. R. Ramasubramaniaraja. Pharmacognostical Phytochemical Including GC-MS Investigation of Ethanolic Leaf Extracts of Abutilon indicum (Linn), Asian Journal of Pharmaceutical Analysis. 2011; 1(4):88-92.
15. Azmir J, Zaidul I.S.M., M.M.Rahmana, K.M.Sharifa, A.Mohamed. F.Sahena, et al., Techniques for exraction of bioactive compounds from plant materials : A Review, Journal of food and engineering. 2013; 117(4): 426-436.
16. Priyanga Rangasamy, Vadakkenchery Salimudheen Hansiya, Palanisamy Uma Maheswari, Thamburaj Suman, Natesan Geetha. Phytochemical Analysis and Evaluation of In vitro Antioxidant and Anti-urolithiatic Potential of various fractions of Clitoria ternatea L. Blue Flowered Leaves, Asian Journal of Pharmaceutical Analysis. 2019; 9(2): 67-76.
17. B. Aruna Sridevi, G. Anil Babu, B. Natasha, P. Srinivasa Babu, Ramadoss Karthikeyan. Preliminary Phytochemical and Physicochemical Studies of Jatropha gossypifolia (L.), Research Journal of Pharmacy and Technology. 2012; 5(5):694-696.
18. Manisha Arora Nagpal, Navneet Nagpal, Sandeep Rahar, Gaurav Swami, Reni Kapoor. Pharmacological and Phytochemical Review on Cassia fistula, Research Journal of Pharmacy and Technology. 2011; 4(2):214-222.
19. Sutar NG, Giri MA, Kendre PN, Syed NL, Singh J. Phytochemical Investigation and Pharmacological Screening of Alienthus excelsa Linn. Leaves as Anthelmintic activity in Earthworm, Research Journal of Pharmacy and Technology. 2010; 3(1):239-243.
20. Singh R, Verma PK, Singh G. Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium, Journal of Intercultural Ethnopharmacology. 2012; 1(2):101-104.
21. Sandhya Mittal, Nidhi Rao, Sudhanshu, Ekta Menghani. Phytochemical and antimicrobial activity of Tectona grandis L, Research Journal of Pharmacy and Technology. 2012; 4(5): 188-191).
22. Evans WC. Trease and Evans. Pharmacognosy. 1989; 33:471.
23. Evans W. Trease and Evans. Pharmacognosy 15th edition Elsevier Health Sciences New York. 2002; 6:21-24.
24. Byahatti VV, Khan AM, Patil SH, Choudhury A. Preliminary Phytochemical Investigation and in vitro Antioxidant Activity of Bergenia ciliata Leaves. Research Journal of Pharmacy and Technology. 2010; 3(2):399-401.
25. Buren J, Robinson W. Formation of complexes between protein and tannic acid. Journal of Agricultural and Food Chemistry. 1969; 47 (7): 772–777.
26. Harborne JB. Phenolic compounds a guide to modern techniques of plant analysis. London: Academic Press. 1973
27. Radheshyam Sharma, Umesh Kumar. Exploration and Phytochemical Estimation of Murraya koenigii Leaves for Pharmaceutical Applications. Asian Journal of Pharmaceutical Analysis. 2019; 9(3):159-168.
28. Sofowara E. Phytochemical Screening of Medicinal Plants and Traditional Medicine in Africa. Ibadan: Spectrum Books Limited.1993.