Author(s):
Rahul Kumar Singh, Rohit Wadhwa, Rajat Garg
Email(s):
Wadhwar131@gmail.com , rahuljadon98@gmail.com , rajatgarg0785@gmail.com
DOI:
10.52711/0974-360X.2021.01010
Address:
Rahul Kumar Singh1, Rohit Wadhwa1*, Rajat Garg2
1Rajiv Academy for Pharmacy, N.H.#2, Mathura Delhi Road, P.O. Chhatikara, Mathura - 281001(U.P).
2Institute of Pharmaceutical Research, GLA University, NH-2 Mathura Delhi Road, P.O Chaumuhan, Mathura - 281406 (U.P.), India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 11,
Year - 2021
ABSTRACT:
The research work was aimed at developing and optimizing erythromycin estolate throat paint solution for improved bioavailability in the oral delivery of based throat paint is prepared by unique method. Potassium iodide, glycerol has been selected based on mouth paint, mucoadhesive strength, and the drug the medication with the goal of treating wooping cough. Erythromycin estolateis released in vitro. A 32factorial prototype was used to preparation the throat paint at concentration of potassium iodide and glycerol was used as an independent variable released in vitro and permeated by percentage.For throat paint, the percentage of mucoadhesion, product consistency,releaseof drugs in vitro, and percentage of rest from permeation were calculated. With mucoadhesive strength, percentage permeation and in-vitro drug releaseperformance, formula f9 has been optimized. Studies of FTIR and have characterised throat paint. Study of stability revealed stable formulation was found.
Cite this article:
Rahul Kumar Singh, Rohit Wadhwa, Rajat Garg. Formulation and Evaluation of Throat Paint of Erythromycin Estolate. Research Journal of Pharmacy and Technology. 2021; 14(11):5808-2. doi: 10.52711/0974-360X.2021.01010
Cite(Electronic):
Rahul Kumar Singh, Rohit Wadhwa, Rajat Garg. Formulation and Evaluation of Throat Paint of Erythromycin Estolate. Research Journal of Pharmacy and Technology. 2021; 14(11):5808-2. doi: 10.52711/0974-360X.2021.01010 Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-11-35
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