Author(s): Jayshree V. Changade, Anil H. Ulemale, P.B. Jondhale

Email(s): jayshreeulemale28@gmail.com , ulemale.anil4@gmail.com

DOI: 10.52711/0974-360X.2021.00987   

Address: Jayshree V. Changade1, Anil H. Ulemale2, P.B. Jondhale3
1Professor, Dravyaguna Department, Dr. D.Y.Patil College of Ayurved and Research Centre, Pimpri, Pune, Dr. D.Y.Patil Vidyapeeth, Pune (Deemed to be University).
2Professor, Surgery Department, KNP Veterinary College, Shirwal, Satara.
3Professor, Shaiya Department, Dr. D.Y.Patil College of Ayurved and Research Centre, Pimpri, Pune.
*Corresponding Author

Published In:   Volume - 14,      Issue - 11,     Year - 2021


ABSTRACT:
Chronic infected wound or non healing ulcer is commonly encountered problem faced in surgico-clinical cases. Wound healing property is most important pharmacological activity of Plaksh or Ficus lacor described by acharya Charaka and Bhavprakash, in an ancient compendia. A male patient aged 55 years, having non healing ulcer on right leg medially above the ankle joint due to trauma, reported to OPD. Wound was irregular with hyper keratinized edges, purulent discharge with foul smell, itching, redness and inflammation. Wound was cleaned with normal saline aseptically and ‘malhar’ or ointment which was prepared by using stem bark of Ficus lacor, was applied locally every day, for thirty days followed by alternate day for next fifteen days. ‘Malhar’ or ointment was prepared as per the formulation mentioned in ‘Ras tarangini’, an ancient compendia. Vitamin C, B complex and Zinc supplement was given orally. After forty five days, wound healed with healthy granulation tissue, purulent discharge and foul smell was totally absent .Bark contains phytochemicals like tannins, polyphenols caffiec acid. It possesses antioxident, anti-inflammatory, antibacterial, astringent activities. Caffeic acid have regulatory mechanism on glucose metabolism in diabetes.


Cite this article:
Jayshree V. Changade, Anil H. Ulemale, P.B. Jondhale. Formulation and Efficacy of Plaksha (Ficus lacor) Ointment in the Management of Non-Healing Ulcer. Research Journal of Pharmacy and Technology. 2021; 14(11):5680-2. doi: 10.52711/0974-360X.2021.00987

Cite(Electronic):
Jayshree V. Changade, Anil H. Ulemale, P.B. Jondhale. Formulation and Efficacy of Plaksha (Ficus lacor) Ointment in the Management of Non-Healing Ulcer. Research Journal of Pharmacy and Technology. 2021; 14(11):5680-2. doi: 10.52711/0974-360X.2021.00987   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-11-12


REFERENCES:
1.    Pushplata Sherekar, Namdeo G. Shinde, Ayurveda: A Need Of Hours, Research J. of Pharmacognosy and Phytochemistry.2019;11(4):229-230
2.    Ambikadatta Shastri, Pranjivan Mehata. Sarth Susruta Samhita Part 1. Sutrasthan, Chapter 12/su.7. Chaukhambha Sanskrit Samsthan, Varanasi 2005.
3.    Swati Rawat, Akhilesh Gupta. Development and Study Of Wound Healing Activity Of An Ayurvedic Formulation. Asian Journal of Research in Pharmaceuticle Scences. 2011;1(1): 26-28
4.    Pranjeevan Mehata, Sushrut Samhita. Chikitsasthan, Part-1, Chap 1/Su.8. Chaukhambha Sanskrit Samsthan, Varanasi 2005.
5.    Gangasahay Pandey,. Charaksamhita of Agnivesha-Part ll. Chap.25/ Su. 84. Chukhambha Sanskrit Samsthan, Varanasi
6.    Pandeya, Gangasahay Krishnachandra Chunekar. Bhavprakashnighantu Chukhambha Bharati Acadamy Varanasi 1999
7.    Pratapkumar Kothapalli, Jagdish S. Sanganal, N.B. Shridhar; Phytopharmacology of Ficus bengalensis-A review. Asian Journal of Pharm. Research. 2014; 4 (4): 201-204.
8.    Goli Venkateshwaru, Anasuri Santosh, Gutha Sumaet.et.al. Ficus religosa –An important Medicinal plant: A Review Folklore Medicine and Traditional Uses. Asian Journal of Pharmaceutical Sciences. 2014 ; 4(1):26-27
9.    Alimuddin Saifi, Rajani Chauhan, J. Dwivedi. An Exploratory study on Ficus bengalensis Linn. Research Journal of Pharmacognosy and Phytochemistry. 2014; 6 (3): 137- 143.
10.    Rajendra K. Jangade. Plant profile of F. religosa: A Review. Research Journal of Science and Technology. 2015; 7 (4):193-196
11.    Preeti, Abhishek Jain,Gaurav kumar et al; Phytochemical composition and antioxidant activity of Ficus elastica Roxb. (Moraceae) ieaves. Research journal of Pharmacy and Technology.2015;8(3):259-264.
12.    The Ayurvedic Pharmacopoeia of India Part l,Vol ll, The Controller of Publications, Civil Line
13.    Quality Standards of Indian Medicinal Plants Vol. l, Published by Indian Council of Medical Research, New Delhi 2003.
14.    S.K. Purohit, R. Solanki. Micro organisms Responsible For Wound Infection On Human Skin. Asian Journal of Research Pharm. Sci. 2013; 3(2): 68-71.
15.    Veena Kanth, Dhammanand Khadkutkar, Dudhmal Tukaram. Antimicrobial activity of Panchvalkala Powder and Ointment. IJMPNP, 2016; 2(1):9-15
16.    Pandit Kashlnath Shastri. Rastarangini Chap.2/su.34. Motilal Banarasidas Prakashan, Varanasi.
17.    Mohd. Yusuf, Mohammad Nasiruddin, Nazneen Sultana et al. Regulatory Mechanism of Caffeic acid on glucose Metabolism in Diabetes. Research Journal of Pharmacy and Technology. 2019; 12(10):4735-4740.

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