Author(s): Arif Nur Muhammad Ansori, Viol Dhea Kharisma, Amaq Fadholly, Martia Rani Tacharina, Yulanda Antonius, Arli Aditya Parikesit

Email(s): yulandaantonius@staff.ubaya.ac.id

DOI: 10.52711/0974-360X.2021.00967   

Address: Arif Nur Muhammad Ansori1, Viol Dhea Kharisma2,3, Amaq Fadholly1, Martia Rani Tacharina4, Yulanda Antonius5*, Arli Aditya Parikesit6 1Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
2Computational Virology and Complexity Science Research Unit, Division of Molecular Biology and Genetics, Generasi Biologi Indonesia Foundation, Gresik, Indonesia.
3Master Program in Biology, Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Malang, Indonesia.
4Department of Veterinary Microbiology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
5Department of Biology, Faculty of Biotechnology, University of Surabaya, Surabaya, Indonesia.
6Department of Bioinformatics, School of Life Sciences, Indonesia International Institute for Life Sciences, Jakarta, Indonesia.
*Corresponding Author

Published In:   Volume - 14,      Issue - 10,     Year - 2021


ABSTRACT:
Known as the causal factor of the recent global COVID-19 pandemic, any SARS-CoV-2 is not the only coronavirus that has constituted a menace to society and taken thousands of human lives. Two previous pandemics were also led by coronaviruses; such as the MERS-CoV in 2012 and another SARS-CoV in 2002. Only five months into existence, SARS-CoV-2 transmitted infection to approximately 75 million people and it has led to more than 1.5 million of deaths all over the world. Unfortunately, there has not been any specific treatment yet for COVID-19 yet and its control is purely empirical. The examinations of the parity between SARS-CoV-2 and SARS-CoV, in terms of their genomics, origin, epidemiology, and pathogenesis, suggested that we may use the previous data of MERS-CoV or SARS-CoV as a guideline for uncovering the effective approach to strive against SARS-CoV-2. Various studies have reported the positive effects of numerous phytochemical compounds against SARS-CoV and MERS-CoV. Interestingly, this idea has been emplyed for SARS-CoV-2, and in silico screening of phytochemical compounds has been performed for identifying the potential candidates for COVID-19 treatment. Curcumin is an example of a natural compound which was demonstrated as potent candidate contrary to SARS-CoV-2 protease derived from the in silico studies. Herein, the occurrence of SARS-CoV-2 and the aplication of alternative medicines for treating coronavirus diseases are briefly reviewed.


Cite this article:
Arif Nur Muhammad Ansori, Viol Dhea Kharisma, Amaq Fadholly, Martia Rani Tacharina, Yulanda Antonius, Arli Aditya Parikesit. Severe Acute Respiratory Syndrome Coronavirus-2 Emergence and Its Treatment with Alternative Medicines: A Review. Research Journal of Pharmacy and Technology 2021; 14(10):5551-7. doi: 10.52711/0974-360X.2021.00967

Cite(Electronic):
Arif Nur Muhammad Ansori, Viol Dhea Kharisma, Amaq Fadholly, Martia Rani Tacharina, Yulanda Antonius, Arli Aditya Parikesit. Severe Acute Respiratory Syndrome Coronavirus-2 Emergence and Its Treatment with Alternative Medicines: A Review. Research Journal of Pharmacy and Technology 2021; 14(10):5551-7. doi: 10.52711/0974-360X.2021.00967   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-10-85


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