Author(s): Maruthi R, Chandan R.S, Barath M, G Naveen Datta, Merryl D’Silva, Kajal Kumari M, Farhan Ahmad, Geetha R

Email(s): rschandan@jssuni.edu.in

DOI: 10.5958/0974-360X.2021.00014.7   

Address: Maruthi R1, Chandan R.S*, Barath M1, Mr. G Naveen Datta2, Ms. Merryl D’Silva2, Ms. Kajal Kumari M3, Mr. Farhan Ahmad3, Ms. Geetha R3
1Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru, JSS Academy of Higher Education and Research, Sri Shivarathreeshwara Nagara, Mysuru- Karnataka, India 570015.
2Department of Pharmaceutics, JSS College of Pharmacy, Mysuru, JSS Academy of Higher Education and Research, Sri Shivarathreeshwara Nagara, Mysuru- Karnataka, India 570015.
3Department of Pharmacy Practise, JSS College of Pharmacy, Mysuru, JSS Academy of Higher Education and Research, Sri Shivarathreeshwara Nagara, Mysuru- Karnataka, India 570015.
*Corresponding Author

Published In:   Volume - 14,      Issue - 1,     Year - 2021


ABSTRACT:
The measurement of teneligliptin in a drug pure in compliance with the ICH Guidelines, an easy and extraction free UV spectrophotometric method, was developed and validated. At 246nm and linearity of concentration of 10-50µg/ml, the drug shows strong absorption. The process for relaying the drug reaction to MeOH was calculated by its absorption maximum (?max) 246nm in order to achieve a colorless solution. In the 10-50µg/ml concentration range, the rule on beer complied. The calibration chart was found to be linear, and the coefficient of correlation (r2) was found to be 0.9952%. The experimental value LOD and LOQ parameters for the proposed procedure are measured, respectively, like 2.25 and 6.83µg/mL. Teneligliptin recovery was reported as 101.58%. To maximize the reaction condition, all of the parameters were analyzed.


Cite this article:
Maruthi R, Chandan R.S, Barath M, G Naveen Datta, Merryl D’Silva, Kajal Kumari M, Farhan Ahmad, Geetha R. Analytical Method Development and Validation of Teneligliptin by UV Spectroscopy. Research J. Pharm. and Tech. 2021; 14(1):75-78. doi: 10.5958/0974-360X.2021.00014.7

Cite(Electronic):
Maruthi R, Chandan R.S, Barath M, G Naveen Datta, Merryl D’Silva, Kajal Kumari M, Farhan Ahmad, Geetha R. Analytical Method Development and Validation of Teneligliptin by UV Spectroscopy. Research J. Pharm. and Tech. 2021; 14(1):75-78. doi: 10.5958/0974-360X.2021.00014.7   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-1-14


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