Author(s): Kapil Kumar Verma, Rupesh K Gautam, Amit Choudhary, Ghanshyam Das Gupta, Shivali Singla, Sachin Goyal

Email(s): kkvmpharm09@gmail.com

DOI: 10.5958/0974-360X.2020.00702.7   

Address: Kapil Kumar Verma1*, Rupesh K Gautam2, Amit Choudhary1, Ghanshyam Das Gupta3, Shivali Singla4, Sachin Goyal4
1School of Pharmacy, Abhilashi University, Mandi-175028, Himachal Pradesh, India.
2MM School of Pharmacy, MM University, Sadopur-Ambala-134007, India.
3ISF College of Pharmacy, Moga-142001, Punjab, India.
4Himalayan Institute of Pharmacy, Kala Amb-173030, Himachal Pradesh, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 8,     Year - 2020


ABSTRACT:
Rumex hastatus (Polygonaceae), known as “Khatimal”, is perennial shrub found as a common weed all over the hills of India and Pakistan. The intact plant is used in traditional and folkloric systems of medicine. In traditional systems of medicine, the plant is reputed for its laxative, tonic agent, diuretic, against rheumatism, skin diseases, piles, bleeding of the lungs, foot and mouth infections, asthma, cough, jaundice, headache, diarrhea, dysentery, fever, weakness and scabies. The whole plant is ascribed to possess medicinal virtues in Ayurvedic and Unani systems of medicine. The review reveals that phytochemical constituents of extensive range have been separated from the plants and it possesses main pharmacological activities like hepatoprotective, antinociceptive, antiinflammatory, antipyretic, antibacterial, phytotoxic, cytotoxic, antidiarrhoeal, neurodegenerative disorders, antitumor and anti-angiogenic potentials. This review highlights the phytochemical, conventional, ethno botanical, pharmacological information available on R. hastatus, which might be obliging for researchers and scientists to find out new element entities responsible for its claimed conventional uses.


Cite this article:
Kapil Kumar Verma, Rupesh K Gautam, Amit Choudhary, Ghanshyam Das Gupta, Shivali Singla, Sachin Goyal. A Review on Ethnobotany, Phytochemistry and Pharmacology on Rumex hastatus. Research J. Pharm. and Tech. 2020; 13(8):3969-3976. doi: 10.5958/0974-360X.2020.00702.7

Cite(Electronic):
Kapil Kumar Verma, Rupesh K Gautam, Amit Choudhary, Ghanshyam Das Gupta, Shivali Singla, Sachin Goyal. A Review on Ethnobotany, Phytochemistry and Pharmacology on Rumex hastatus. Research J. Pharm. and Tech. 2020; 13(8):3969-3976. doi: 10.5958/0974-360X.2020.00702.7   Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-8-75


REFERENCES:
1.    Prajapati and Purohit. Agro’s colour atlas of medicinal plants. Agrobios 2003; 1-3.
2.    Gupta LM and Raina R. Side effects of some medicinal plants. Curr sci 1998; 75: 897-900.
3.    Valiathan MS. Healing plants. Curr Sci 1998; 75:1122-1127.
4.    Manandhar NP. Ethnobotanical notes on certain medicinal plants used by Tharus of Dang-Deokhuri District Nepal. International Journal of Crude Drug Research. 1985; 23(4):153-159.
5.    Manandhar NP. Ethnobotany of Jumia District Nepal International Journal of Crude Drug Research. (1986); 24(2):81-89.
6.    Manandhar NP. Traditional medicinal plants used by tribals of Lamjung District Nepal. International Journal of Crude Drug Research. (1987); 25(4): 236-240.
7.    Manandhar NP. Folk-lore medicine of chitwan district, Nepal. Ethnobotany. 1989; 2: 31-38.
8.    Manandhar NP. Medicinal plants used by Chepang tribes of Makawanpur District Nepal. Fitoterapia. 1989; 60(i): 61-68.
9.    Manandhar NP. Medicobotany of gorkha district Nepal An elucidation of medicinal plants. International Journal of Crude Drug Research. 1990 ;28(1): 17-25.
10.    Manandhar NP. Traditional phytotherapy of dannwar tribes of Kamlakhonj in Sindhuli District Nepal. Fitoterapia. 1990; 61(4):325-331.
11.    Manandhar NP. Useful wild nlants of Nepal. franz steiner verlag wiesbaden, GMBH, Stuttgart, West Germany. 1989; 1-102.
12.    Bhatterai NK, Folk medicinal use of plants for respiratory complaints in central Nepal. Fitoterapia. 1993 ;64: 163-169.
13.    Shrestha 1. and Joshi N. Medicinal plants of the lele village of datipur district nepal. International Journal of Pharmacognosy. 1993; 31(2):130-134.
14.    Taylor RS, Manandhar NP and Towers. GHN Screening of selected medicinal plants of nepal for antimicrobial activities. Journal of Ethnopharmacology.1995; 46: 153-159.
15.    Bhakuni DS Dhar, ML Dhhawan, BN and Mehrotra BN. Screening of Indian plants for biological activity part II. Indian Journal of Experimental Biology. 1969; 7:250-262.
16.    Saleh NAM, El Hadidi MN, Arafa RFM. Flavonoids and anthraquinones of some Egyptian Rumex species (Polygonaceae). Biochemical Systematics and Ecology.1993; 21: 301–303.
17.    Pardode Santayana, M Tardío, J Morales R. The gathering and consumption of wild edible plants in the Campoo (Cantabria, Spain). International Journal of Food Science and Nutrition. 2005; 56: 529–542.
18.    Giday M, Asfaw Z, Woldu Z. Medicinal plants of the meinit ethnic group of Ethiopia: An ethnobotanical study. Journal of Ethnopharmacology. 2009; 124: 513–521.
19.    Cakilcioglu U, Türkoglu I. An ethnobotanical survey of medicinal plants in Sivrice (Elazig- Turkey). Journal of Ethnopharmacology. 2010; 132: 165–175.
20.    Anonymous, The Wealth of India: A Dictionary of Indian Raw Materials and Industrial Products. Vol. IX, New Delhi: Council of Scientific and Industrial Research. 1956; 92.
21.    Boulos L, EI-Hadidi, M N, The Weed Flora of Egypt American University Press. Cairo1984.
22.    Ahmad M, Shazia S, Syed FH, Taibi BH, Sofia R, Muhammad Z and Mir AK. An ethnobotanical study of medicinal plants in high mountainous region of Chail valley (District Swat- Pakistan). Journal of Ethnobiology and Ethnomedicine. 2014; 10(1):36.
23.    Abbasi AM, Khan MA, Shah MH, Shah MM, Pervez A and Ahmad M. Ethnobotanical appraisal and cultural values of medicinally important wild edible vegetables of Lesser Himalayas-Pakistan. Journal of Ethnobiology and Ethno Medicine. 2013; 9(1):66.
24.    Sahreen S, Khan MR and Khan RA.Comprehensive assessment of phenolics and antiradical potential of Rumex hastatus D. Don. roots. BMC Complementary and Alternative Medicine. 2014; 14(1):47.
25.    Zhang LS, Li Z, Mei RQ, Liu GM, Long CL, Wang YH and Cheng YX. Hastatusides A and B two new phenolic glucosides from Rumex hastatus. 2009;92 (4): 774-778
26.    Manandhar NP. Plants and people of Nepal. Timber press.2002
27.    Khare CP. Indian Medicinal Plants, An Illustrated Dictionary Springer-Verlag. Berlin pg 2007; 699-700.
28.    Ali SM, Qaiser I. Flora of Pakistan Department of Botany University of Karachi. 2001; 22-35.
29.    Anjen L, Grabovskaya-Borodina, AE and Mosyakin, SL Rumex. Flora of China. 2003; 333-341.
30.    Das PN, Purohit SS, Sharma AK and Kumar T. A handbook of medicinal plants. Jodhpur India Agrobios. 2003; 118.
31.    Hussain M, and Ghani A. Herbal remidies used for gastrointestinal disorders in Kaghan valley. NWFP Pakistan. Pak. J. Weed Sci. Res. 2008;14(3-4) :169-200.
32.    Taylor RSL, Hudson JB, Manandhar NP and Towers GHN. Antiviral activities of medicinal plants of southern Nepal. Journal of Ethnopharmacology. 1996;53 (2):105-110.
33.    Manan Z, Razzaq A and Islam M. Diversity of medicinal plants in Wari subdivision district Upper Dir Pakistan. Pakistan Journal of Plant Sciences (Pakistan). 2007; 13(1): 21-28.
34.    Ullah R, Iqbal ZHZ, Hussain J, Khan FU, Khan N, Muhammad Z Ayaz, S Ahmad, S Rehman, NU and Hussain I. Traditional uses of medicinal plants in Darra Adam Khel NWFP Pakistan. Journal of Medicinal Plants Research. 2010; 4(17):1815-1821.
35.    Khan M, Kumar S, and Hamal IA. Medicinal plants of Sewa river catchment area in the Northwest Himalaya and its implication for conservation. Ethnobotanical Leaflets. 2009;(9):5.
36.    Islam M, Ahmad H, Rashid A, Razzaq A, Akhtar N and Khan I. Weeds and medicinal plants of Shawar valley, district Swat. Pak. J. Weed Sci. Res,2006; 12(1-2):83-88.
37.    Hussain F, Islam M, and Zaman A, 2006. Ethnobotanical profile of plants of shawar valley, District Swat.Pakistan. Int J Biol Biotechnol. 2006; 3(2) :301-7.
38.    Kumar M, Sheikh MA, and Bussmann, RW, Ethnomedicinal and ecological status of plants in Garhwal Himalaya, India. Journal of Ethnobiology and Ethnomedicine. 2011;7(1):32.
39.    Abbasi AM, Shah MH, Li T, Fu X, Guo X and Liu RH. Ethno medicinal values, phenolic contents and antioxidant properties of wild culinary vegetables. Journal of Ethnopharmacology.2015; 162: 333-345.
40.    Editorial Commission of China. In Flora of Chinese Academy of Sciences. Science Press Beijing China 1998; 151.
41.    Coburn B, Some native medicinal plants of the western Gurung. 1984; 55–87.
42.    Pohle P. Useful plants of Manang district: a contribution to the Ethnobotany of the Nepal Himalaya.1990.
43.    Jang DS, Kim JM, Kim, JS 24-nor-Ursane type triterpenoids from the stems of Rumex japonicus. Chemical and Pharmaceutical Bulletin. 2005; 53: 1594–1596.
44.    Wegiera M, Smolarz HD, Wianowska D, Dawidowicz AL. Anthracene derivatives in some species of Rumex L, genus. Acta Societas Botanica Polonica. 2007; 76:103–108.
45.    Mei R, Liang H, Wang J, Zeng L, Lu Q, Cheng Y. New seco-anthraquinone glucosides from Rumex nepalensis. Planta Medica. 2009; 75: 1162–1164.
46.    Liang HX, Dai HQ, Fu HA, Dong XP, Adebayo AH, Zhang LX, Cheng YX. Bioactive compounds from rumex plants. Phytochemistry Letters. 2010; 3:181–184.
47.    Demirezer LO, Kuruüzüm A, Bergere I, Schiewe HJ, Zeeck A. Five naphthalene glycosides from the roots of Rumex patientia. Phytochemistry. 2001; 56: 399–402.
48.    El-Hawary SA, Sokkar NM, Ali ZY, Yehia MM. A profile of bioactive compounds of Rumex vesicarius L. Journal of Food Science. 2011; 76:1195–1202.
49.    Gescher K, Hensel A, Hafezi W, Derksen A, Kühn J. Oligomeric proanthocyanidins from Rumex acetosa L. inhibits the attachment of herpes simplex virus type-1. Antiviral Research. 2011; 89: 9–18.
50.    Nadkarni K, and Nadkarni AK. Indian Materia Medica. Popular Prakashan Pvt. Ltd. Bombay. 1976; 799.
51.    Abbasi AM, Khan MA, Ahmad M, Zafar M, Khan H, Muhammad N and Sultana S. Medicinal plants used for the treatment of jaundice and hepatitis based on socio-economic documentation. African Journal of Biotechnology. 2009; 8(8): 1643-1650.
52.    Tiwari RD and Sinha KS. Chemical Examination of Rumex-Hastatus D-Don Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry. 1980;19(6):531-532.
53.    Yang Y, Yan YM, Wei W, Luo J, Zhang LS, Zhou X J, Wang PC, Yang YX and Cheng YX. Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy. Bioorganic and Medicinal Chemistry letters. 2013; 23(13):3905-3909.
54.    Makkar HPS, Singh B, Vats SK and Sood RP. Total phenols tannins and condensed tannins in different parts of Rumex hastatus. Bioresource Technology. 1993; 45(1):69-71.
55.    Hameed I, Dastagir G and Hussain F. Nutritional and elemental analyses of some selected medicinal plants of the family Polygonaceae. 2008; 40(6): 2493-2502.
56.    Muhammad S, Shah MT and Khan S. Heavy metal concentrations in soil and wild plants growing around Pb–Zn sulfide terrain in the Kohistan region. Northern Pakistan. Microchemical Journal. 2011; 99(1): 67-75.
57.    Sahreen S, Khan MR and Khan RA, Ameliorating effect of various fractions of Rumex hastatus roots against hepato-and testicular toxicity caused by CCl4. Oxidative medicine and cellular longevity. 2013;14.
58.    Sahreenss S, Khan MR and Khan RA. Evaluation of Rumex hastatus leaves against hepatic fibrosis: a rat model. BMC Complementary and Alternative Medicine. 2017;17(1):435.
59.    Kamal Z, Ullah M, Ahmad S, Ullah F, Sadiq A, Ayaz M, Zeb A and Imran M. Exvivo antibacterial. phytotoxic and cytotoxic potential in the crude natural phytoconstituents of Rumex hastatus D. Don. Pak J Bot. 2015; 47(SI):293-299.
60.    Afzal S, Tabassum S, Gilani MA, Hussain N, Farooq R, Zahid S, Shah AT and Khan A. Total phenolic content. in vitro vadical scavenging and antimicrobial activities of whole plant rumex hastatus. Science International. 2014; 26(2): 721-727.
61.    Singh S, Kaur R and Sharma S. Antinociceptive, antiinflammatory and antipyretic activities of Rumex hastatus D. don stem and roots. Der Pharmacia Sinica,2013; 4(3) :95-102.
62.    Ahmad S, Ullah F, Sadiq A, Ayaz M, Imran M, Ali I, Zeb A, Ullah F and Shah MR. Chemical composition. antioxidant and anticholinesterase potentials of essential oil of Rumex hastatus D. Don collected from the North West of Pakistan. BMC Complementary and Alternative Medicine. 2016; 16(1) :29.
63.    Ahmad S, Ullah F, Zeb A, Ayaz M, Ullah F and Sadiq A. Evaluation of Rumex hastatus D. Don for cytotoxic potential against HeLa and NIH/3T3 cell lines. chemical characterization of chloroform fraction and identification of bioactive compounds. BMC Complementary and Alternative Medicine, 2016; 16(1):308.
64.    Ahmad S, Ullah F, Ayaz M, Zeb A, Ullah F and Sadiq A. Antitumor and anti-angiogenic. potentials of isolated crude saponins and various fractions of Rumex hastatus D. Don. Biological Research. 2016; 49(1) :18.
65.    Shakuntala BP, Sachan N, Chandra P and Gahlot K. Evaluation of antidiarrhoeal activity of extract from roots of Rumex hastatus (family: Polygonaceae) on experimental animals. J Appl Pharm Sci. 2011; 1(6):182-5.

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