Author(s): Simanchal Dash


DOI: 10.5958/0974-360X.2020.00680.0   

Address: Dr. Simanchal Dash
Department of Chemistry, Roland Institute of Technology, Berhampur, Odisha, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 8,     Year - 2020

The compound 2-p-anisilidienyl 3-(benzothiazolyl-2’)hydrazono-5-p-anisilidiene-4 thiazolidinone has been synthesized by taking 2-hydrazino benzothiazole as a starting material. Regrettably the compound has poorly soluble in aqueous solvent. Consequently its inclusion complex is build up by taking ß-cyclodextrin. The physical and spectral characteristics conforms formation of inclusion complex. Although different methods available for the preparation of inclusion complexes, but co-precipitation method is used here. Phase solubility diagram is constructed for selection of 1:1 stoichiometric ratio between compound and ß-cyclodextrin. The free energy of activation and thermodynamically permittivity of the compounds predicts stability of the complexes.

Cite this article:
Simanchal Dash. Studies on inclusion complexes of 2-p-anisilidienyl 3-(benzothiazolyl-2’) hydrazono-5-p-anisilidiene-4 thiazolidinone with β-cyclodextrin. Research J. Pharm. and Tech. 2020; 13(8):3843-3848. doi: 10.5958/0974-360X.2020.00680.0

Simanchal Dash. Studies on inclusion complexes of 2-p-anisilidienyl 3-(benzothiazolyl-2’) hydrazono-5-p-anisilidiene-4 thiazolidinone with β-cyclodextrin. Research J. Pharm. and Tech. 2020; 13(8):3843-3848. doi: 10.5958/0974-360X.2020.00680.0   Available on:

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