Author(s): Vaishnav Lal C. L, R. S Chandan, Maruthi. R, Anand Kumar Tengli

Email(s): rschandan@jssuni.edu.in

DOI: 10.5958/0974-360X.2020.00659.9   

Address: Vaishnav Lal C. L, R. S Chandan, Maruthi. R, Anand Kumar Tengli
Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru, JSS Academy of Higher Education and Research, Sri Shivarathreeshwara Nagara, Mysuru- Karnataka, India 570015.
*Corresponding Author

Published In:   Volume - 13,      Issue - 8,     Year - 2020


ABSTRACT:
Organophosphates are a group of pesticides that were developed in the 1940s in Germany andsoon became a significant defense against agricultural pests. The organophosphate Dichlorvos is a commonly used group of pesticide is a broad-spectrum organophosphate compound having insecticidal activity. Dichlorvos is a cholinesterase inhibitor exhibiting stomach, contact and systemic mode of action. The development of bioanalytical method is the process of developing a procedure for the detection and quantification of a compound of interest in a biological fluid. A simple, reliable, fast, accurate and economical RP-UFLC method have been developed and validated for quantitative determination of Dichlorvos. The RP-UFLC procedure is developed by using ACN and Millipore water 50:50 v/v as mobile phase, Flow rate is maintained at 1.5mL/minute. Detection of Dichlorvos was performed by using PDA detector at 200nm. By this RP-UFLC procedure retention time (RT) of Dichlorvos was identified at 2.9 min.


Cite this article:
Vaishnav Lal C. L, R. S Chandan, Maruthi. R, Anand Kumar Tengli. Bio-Analytical Method Development and Validation of Dichlorvos Pesticide by RP-UFLC Method. Research J. Pharm. and Tech. 2020; 13(8):3725-3728. doi: 10.5958/0974-360X.2020.00659.9

Cite(Electronic):
Vaishnav Lal C. L, R. S Chandan, Maruthi. R, Anand Kumar Tengli. Bio-Analytical Method Development and Validation of Dichlorvos Pesticide by RP-UFLC Method. Research J. Pharm. and Tech. 2020; 13(8):3725-3728. doi: 10.5958/0974-360X.2020.00659.9   Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-8-32


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