Author(s): S. Geetha, K. Vijayakumar

Email(s): knvijaykumar72@gmail.com

DOI: 10.5958/0974-360X.2020.00601.0   

Address: S. Geetha, K. Vijayakumar*
Department of Chemistry, M. Kumarasamy College of Engineering, Karur- 639113, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 7,     Year - 2020


ABSTRACT:
A modest and a capable method was enhanced underway of tetrazole moiety derivatives got from the different diamines buildup with 2-amino-benzoic acid and numerous substituted benzoylchloride responses have for some time been an alluring objective for the advancement of agents against bacterial and parasitic diseases and also cancer. The point of this examination contemplate is to find a novel engineered lead compounds for future advancement. Another arrangement of benzimidazole analogs is outlined have been incorporated, it has treated with phosphorous pentachloride and sodiumazide response to yield benzimidazole clubbed with tetrazole moiety derivative structure illustration of the new was satisfied in view of elemental analysis (C, H, N), FT-IR, 1H-NMR, 13CNMR, and Mass spectrometry, and screening of anticancer ponders additionally recorded.


Cite this article:
S. Geetha, K. Vijayakumar. Synthesis, Characterization and the anti HIV1 behavior of some Novel Clubbed Benzimidazole derivatives approaches. Research J. Pharm. and Tech. 2020; 13(7): 3383-3388. doi: 10.5958/0974-360X.2020.00601.0

Cite(Electronic):
S. Geetha, K. Vijayakumar. Synthesis, Characterization and the anti HIV1 behavior of some Novel Clubbed Benzimidazole derivatives approaches. Research J. Pharm. and Tech. 2020; 13(7): 3383-3388. doi: 10.5958/0974-360X.2020.00601.0   Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-7-61


REFERENCES:
1. Barker, A. J. J. Eur. Pat. 1995, Chem. Abstr. 1995, 122, 214009.
2. Sushil K. Kashaw.; Varsha Kashaw.; Pradeep Mishra.; Jain, N. K. Arkivoc. 2008, 14, 17.
3. Gravatt, G. L.; Baguley, C.; Wilson, W. R. J. Med. Chem. 1994, 37, 4338.
4. Divaeva, L. N.; Kuzmenko, T. A.; Morkovnik, A. S.; Komissarov, V. N. Chem. Heter. Compds. 2006, 42, 463.
5. Davoodnia, A.; Roshani, M.; Saleh Nadim, E.; Bakavoli, M.; Tavakoli Hoseini, N. Chin. Chem. Lett. 2007, 18, 1327.
6. Kus, C.; Aylan-Kicigil, G.; Iscan, M. Arch. Phar. Res. 2004, 27, 156.
7. Abdel-Rahman, A. E.; Mahmoud, A. M.; El-Naggar, G. M. Pharmazie. 1983, 38, 589.
8. Soliman, F. S. G.; Rida, S. M.; Kappe, T. Arch. Pharm. 1984, 317, 951.
9. Ozden, S.; Atabey, D.; Yildiz, S.; Goker, H. Bioorg. Med. Chem. 2005, 13, 1587.
10. Sztanke, K.; Pasternak, K.; Sidor-Wojtowicz, A.; Truchlinska, J.; Jozwiak, K. Bioorg. Med. Chem. 2006, 14, 3635.
11. Porcari, A. R.; Devivar, R. V.; Kucera, L. S.; Drach, J. C.; Townsend, L. B. J. Med. Chem. 1998, 41, 1251.
12. Roth, M.; Morningstar, M. L.; Boyer, P. L.; Hughes, S. H.; Bukheit, R. W.; Michejda C. J. J. Med. Chem. 1997, 40, 4199.
13. Samia, R.; Soda, A.; El-Hesham, M.; Fahmy, T. Y. Arch. Pharm. Res. 2006, 29, 826.
14. Fukuda, T.; Saito, T.; Tajima, S.; Shimohara, K.; Ito, K. Arzneim.-Forsch./Drug Res. 1984, 34, 805.
15. Nakano, H.; Inoue, T.; Kawasaki, N.; Miyataka, H.; Matsumoto, H.; Taguchi, T.; Inagaki, N.; Nagai. H.; Satoh, T. Chem. Pharm. Bull. 1999, 47, 1573.
16. Can-Eke, B.; Puskullu, M. O.; Buyukbingol, E.; Iscan, M. Chem. Bio. Inter. 1998, 113, 65.
17. Kus, C.; Ayhan-Kilcigil, G.; Can-Eke, B.; Iscan, M. Arch. Pharm. Res. 2004, 27, 156.
18. Ayhan-Kilcigil, G.; Kus, C.; Coban, T.; Can-Eke, B.; Iscan, M. J. Enz. Inh. and Med. Chem. 2004, 19, 129.
19. Goker, H.; Ayhan-Kilcigil, G.; Tuncbilek, M.; Kus, C.; Ertan, R.; Kendi, E.; Ozbey, S.; Fort, M.; Garcia, C.; Farre, A. J. Heterocycles. 1999, 51, 2561.
20. Khairnar, V. L.; Lockhande, S. R.; Patel, M, R.; Khadse, B. G. Chem. Abstr. 1981, 95, 203833h.
21. Kuchkguzel, I.; Kuchkguzel, G.; Rollas, S.; Kiraz, M. Bioorg. & Med. Chem. Lett. 2001, 11, 1703.
22. Popp, F. D. J. Org. Chem. 1980, 26, 1566.
23. Popp, F. D. J. Med. Chem. 1911, 7, 210.
24. Kruse, L. L.; Ladd, D. L.; Harrsch, P. B.; McCabe, F. L.; Mong, S. M.; Faucette, L.; Johnson, R. J. Med. Chem. 1989, 32, 409.
25. Islam, I.; Skibo, E. B.; Dorr, R. T.; Alberts, D. S. J. Med. Chem. 1991, 34, 2954.
26. Ramla, M. M.; Omar, M. A.; Tokuda, H.; El.Diwani, H. I. Bioorg. & Med. Chem. 2007, 15, 6489.
27. Denny, W. A.; Rewcastle, G. W.; Bagley, B. C. J. Med. Chem. 1990, 33, 814.
28. Tatsuta, M.; Kataoka, M.; Yasoshima, K.; Sakakibara, S.; Shimazaki, M.; Yura, T.; Li, Y.; Yamamoto, N.; Gupta, J.; Urbahns, K. Bioorg. & Med. Chem. Lett. 2005, 15, 2265.
29. Carlsson, E.; Lindberg, P.; Unge, S. Chem. Br. 2002, 5, 42.
30. Richter, J. E. Am. J. Gastroenterology. 1997, 92, 30.
31. Hazelton, J. C.; Iddon, B.; Suschitzky, H.; Woolley, L. H. Tetrahedron. 1995, 51, 10771.
32. Karen, K. Antiviral Res. 2006, 71, 154.
33. Gardiner, J. M.; Loyns, C, R.; Burke, A.; Khan, A.; Mahmood, N. Bioorg. Med. Chem. Lett. 2003, 13, 657.
34. Li, Y. F.; Wang, G. F.; Luo, Y.; Huang, W. G.; Tang, W.; Feng, C. L.; Shi, L. P.; Ren, Y. D.; Zuo, J. P.; Lu, W. Eur. J. Med. Chem. 2007, 42, 1358.
35. Young, W. B.; Sprengeler, P.; Shrader, W. D.; Li, Y.; Rai, R.; Verner, E.; Jenkins, T.; Fatheree, P.; Kolesnikov, A.; Janc, J. W.; Cregar, L.; Elrod, K.; Katz, B. Bioorg. Med. Chem. Lett. 2006, 16, 710.
36. Mertens, A.; Muller-Beckmann, B.; Kampe, W.; Holck, J. P.; Vonder Saal, W. J. Med. Chem. 1987, 30, 1279.
37. Vinodkumar, R.; Vaidya, S. D.; Siva Kumar, B. V.; Bhise, U. N.; Bhirud, S. B.; Mashelkar, U. C. J. Med. Chem. 2008, 43, 986.
38. Andrzejewska, M.; Yepez-Mulia, L.; Tapia, A.; Cedillo-Rivera, R.; Laudy, A. E.; Starosciak, B. J.; Kazimierczuk, Z. Eur. J. Pharm. Sci. 2004, 21, 323.
39. Bhusahan Baviskar, Bhagyesh Baviskar, Suvarna Chuedhary, Kanchanparwani, Pinky Balani, Vikrant Salode, Rasayan J. Chem. 2009, 2 , 186.
40. Rahul R. Nagawade, Devanand B. Shinde, Chin. Chem. Lett. 2006, 17, 453.
41. Ramanatham Vinodkumar, Sanjay Dashrath Vaidya, Umesh Nanasaheb Bhise, Shekar Bhaskar Bhirud, ARKIVOC. 2008, 14, 37.
42. Zhan-Hui Zhang, Tong- Shuang Li, Jian- Jiong Li. Monat, Fur. Chem. 2007, 138 89.
43. S. B. Jadhav, R. A. Shastri, Bagul, K. R Gaikwad, Ind. J. Heter. Chem. 2009, 18 319.
44. Canan Kus. Nurten Altanlar. Turk. J. Chem, 2003, 27, 35
45. S. S. Mahajan, R. G. Nandre, Ind. J. Chem, 2006, 45B, 1756
46. R. R. Varma, S. V. Athlekar, A. S. Bobade, L. S. Patil, A. S. Chowdhary, Ind. J. Heter. Chem, 2010, 19, 245

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank

Journal Policies & Information


Recent Articles




Tags


Not Available