Author(s): Devendra S. Shirode, Priyatama Powar, Brijendra B. Jain, Amit Agarwal

Email(s): dssdypcop@gmail.com

DOI: 10.5958/0974-360X.2020.00592.2   

Address: Devendra S. Shirode1*, Priyatama Powar1, Brijendra B. Jain2, Amit Agarwal3
1Dept. of Pharmacology, Dr. D. Y. Patil College of Pharmacy, Akurdi, Pune - 410044.
2Indrayani Institute of Pharmaceutical Education and Research, Talegaon Dabhade, Pune - 410507.
3Aditya College of Pharmacy, Sherganj, Satna, Madhya Pradesh - 485001.
*Corresponding Author

Published In:   Volume - 13,      Issue - 7,     Year - 2020


ABSTRACT:
The effect of 70 % ethanol extract of aerial part of Blumea lacera (BLEE) was investigated in rats to evaluate antiulcer activity against ethanol, indomethacin and pyloric ligation induced ulcer models. Pretreatment with BLEE (200mg/kg and 400mg/kg) has shown dose dependant decrease in ulcer index in all the experimental models of ulcers and also reduced the total acidity, free acidity, gastric volume and increased the pH (pyloric ligation model) with respect to control. Hence, it is concluded that BLEE possess significant antiulcer activity.


Cite this article:
Devendra S. Shirode, Priyatama Powar, Brijendra B. Jain, Amit Agarwal. Antiulcer effect of Blumea lacera against Gastric ulcers in rats. Research J. Pharm. and Tech. 2020; 13(7): 3340-3342. doi: 10.5958/0974-360X.2020.00592.2


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