Zeena Fernandes, Prasanna Shama Khandige, Ullas Prakash D’Souza
Zeena Fernandes, Prasanna Shama Khandige*, Ullas Prakash D’Souza
Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Paneer, Derlakatte P.O, Mangaluru-574160 India.
Volume - 13,
Issue - 7,
Year - 2020
The present study was undertaken to evaluate the anti-anxiety activity of the ethanolic and aqueous extract of Perseaamericana bark by the elevated plus maze method using swiss albino mice. The anti-anxiety activity of the ethanolic and aqueous extracts at doses 100, 200 and 400mg/kg body weight, was evaluated using the elevated plus maze method. Diazepam (0.5mg/kg) was used as the standard drug for comparison. In this study the ethanolic and the aqueous extract (200mg/kg and 400mg/kg) showed significant increase in the following parameters: % number of open arm entries and % time spent in open arms in Elevated Plus maze method. From the present study it can be concluded that Perseaamericana bark showed a significant anti-anxiety activity.
Cite this article:
Zeena Fernandes, Prasanna Shama Khandige, Ullas Prakash D’Souza. Anxiolytic potential of Perseaamericana M. by elevated plus maze test. Research J. Pharm. and Tech. 2020; 13(7): 3326-3328. doi: 10.5958/0974-360X.2020.00590.9
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