Fetal Hemoglobin (HbF) levels in Sickle cell anemia patients in Lattakia, Syria

Rana I. Ahmad; Haider A. Al-Barry; Salwa I. Salloum

doi:10.5958/0974-360X.2020.00575.2

Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)

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Fetal Hemoglobin (HbF) levels in Sickle cell anemia patients in Lattakia, Syria

Author(s): Rana I. Ahmad, Haider A. Al-Barry, Salwa I. Salloum

Email(s): ranaad83@gmail.com

DOI: 10.5958/0974-360X.2020.00575.2

Address: Rana I. Ahmad, Haider A. Al-Barry, Salwa I. Salloum
Department of Laboratory Medicine, Faculty of Medicine, Al Andalus University for Medical Sciences, Al Qadmus, Tartus, Syria.
*Corresponding Author

Published In: Volume - 13, Issue - 7, Year - 2020

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ABSTRACT:
Sickle cell anemia (SCA) is a chronic hemolytic disorder. It is considered as a major health problem in Syria. The risk of this disease varies among patients worldwide. Fetal hemoglobin (HbF) decreases the severity of SCA by inhibiting the polymerization of sickle hemoglobin (HbS). The aim of this study is to determine the HbF levels in SCA patients. Blood samples were collected from 175 SCA patients. The level of HbF was more than 10%, High level of HbF in 126/175 Patients. The mean of HbF levels was 24.75± 18.8%, and varied according to age, gender, SCD complications. The relation between HbF and SCA complications is still unclear, therefore, more studies were recommended.

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Cite this article:
Rana I. Ahmad, Haider A. Al-Barry, Salwa I. Salloum. Fetal Hemoglobin (HbF) levels in Sickle cell anemia patients in Lattakia, Syria. Research J. Pharm. and Tech. 2020; 13(7): 3246-3248. doi: 10.5958/0974-360X.2020.00575.2

Cite(Electronic):
Rana I. Ahmad, Haider A. Al-Barry, Salwa I. Salloum. Fetal Hemoglobin (HbF) levels in Sickle cell anemia patients in Lattakia, Syria. Research J. Pharm. and Tech. 2020; 13(7): 3246-3248. doi: 10.5958/0974-360X.2020.00575.2 Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-7-35

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