Author(s): Susmita Basak, K Ishwar Bhat

Email(s): bhatishwark@nitte.edu.in

DOI: 10.5958/0974-360X.2020.00558.2   

Address: Susmita Basak, K Ishwar Bhat*
Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, NITTE (Deemed to be University), Paneer, Deralakatte- 575018, Mangalore, Karnataka, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 7,     Year - 2020


ABSTRACT:
A series of novel phenylhydrazinylidene-pyrazoline (PZ1-PZ8) has been successfully synthesized from (1E,3E)-4-phenyl-1-(2-phenylhydrazinylidene) but-3-en-2-one derivatives by cyclization reaction using hydrazine hydrate in the presence of acetic acid and ethanol as an acid catalyst. All the compounds were characterized by Infrared spectroscopy and confirmed by 1H Nuclear Magnetic Resonance, Mass spectroscopy and elemental analysis. All the compounds have been screened for their antioxidant activity. Most of the compounds showed promising activity and can be used as a potential antioxidant drugs.


Cite this article:
Susmita Basak, K Ishwar Bhat. Synthesis, Characterization and Anti-oxidant Activity of some Novel Pyrazoline derivatives. Research J. Pharm. and Tech. 2020; 13(7): 3156-3162. doi: 10.5958/0974-360X.2020.00558.2


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