Author(s): Ruheena Yasmeen, N. Krishna Reddy, Marina. G. D’ Souza, B. Swathi, Anas Abdul Waheed, Katakam Chinmayee, J. Vineeth Reddy

Email(s): ruheena.y786@gmail.com

DOI: 10.5958/0974-360X.2020.00557.0   

Address: Dr. Ruheena Yasmeen1, Dr. N. Krishna Reddy2, Dr. Marina. G. D’ Souza3, Dr. B. Swathi3, Anas Abdul Waheed3, Katakam Chinmayee3, J. Vineeth Reddy3
1Department of Pharm. D (Pharmacy Practice), Nizam Institute of Pharmacy, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Yadadri Bhuvanagiri (Dist)-508284, Telangana, India.
2Department of Cardiology, Durgabai Deshmukh Hospital, Vidya Nagar, Hyderabad.
3Bharat School of Pharmacy, Mangalpally (Village), Ibrahimpatnam (M), Ibrahimpatnam, Rangareddi (Dist), Hyderabad - 500 007 Telangana, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 7,     Year - 2020


ABSTRACT:
Introduction: MI is the leading cause of adult death in the United States (US). It is the predominant cause and responsible for more than 80% of CVD deaths in India. Objective: The objective of this study is to compare the effectiveness, adverse effects, mortality and safety profile of two anti-coagulants (LMWH & UFH) in the patients of acute coronary syndrome (NSTEMI). Methodology: A prospective observation study conducted on 70 adult patients at Durgabhai Deshmukh Hospital and Research Centre, Hyderabad on patients admitted for elective surgery for a period of six months. Results: Among 70 patients 56(80%) are males and 14 (20%) are females. Among all age groups major numbers of NSTEMI patients are seen in 51-60 years (30%). Among all patients 56 out of 70 patients i.e., 80% are with chest pain as chief complaint, 19 patients i.e., 27% are with sweating as chief complaint, 21 patients are with shortness of breath (SOB) as chief complaint i.e., 30% and 9 patients are with palpitations as chief complaint i.e., 13%. Among all patients 8 out of 70 patients suffered gastric bleeding i.e., 11.4% and 1 out of 70 patients suffered from intracranial bleeding i.e., 1.42%.Among all patients 9 patients out of 70 suffered with heart failure i.e., 12.85%, 22 patients out of 70 suffered with tachyarrhythmia i.e., 31.4%, and 13 patients suffered local bleeding i.e., 18.57%. Conclusion: From the study it is concluded that, patients with NSTEMI are given both the regimens i.e., low molecular weight heparin and un fractionated heparin and found that 27% more risk is observed in regimen 2 i.e., un fractionated heparin until the limited follow up that has done.


Cite this article:
Ruheena Yasmeen, N. Krishna Reddy, Marina. G. D’ Souza, B. Swathi, Anas Abdul Waheed, Katakam Chinmayee, J. Vineeth Reddy. Study of Anticoagulants low molecular weight heparin and Unfractionated heparin in the management of Non-St elevation Myocardial Infarction. Research J. Pharm. and Tech. 2020; 13(7): 3151-3155. doi: 10.5958/0974-360X.2020.00557.0


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