Author(s): K. Kousalya, T. Priya, P. Venkatalakshmi

Email(s): venkatalakshmisathish@gmail.com

DOI: 10.5958/0974-360X.2020.00556.9   

Address: K. Kousalya1, T. Priya1, P. Venkatalakshmi1,2
1PG Research Department of Biochemistry, STET Women’s College, Mannargudi.
2Department of Biochemistry, PSG College of Arts and Science, Coimbatore.
*Corresponding Author

Published In:   Volume - 13,      Issue - 7,     Year - 2020


ABSTRACT:
Chronic inflammation is the underlying factor in causing multitude of human ailments ranging from arthritis to cancer. Amidst the emerging synthetic drugs, people started re-evaluating traditional plant based medicines because of the efficacy and safety of herbal medicine. Hence in the present study, efforts are made to validate the anti-inflammatory potential of four medicinal plants using in-vitro procedures. Ten different concentrations of aqueous extracts of selected medicinal plants ranging from 0.01-10mg/ml were taken. At a concentration of 10 mg/ml Erythrina indica has shown 74.15% of protein denaturation inhibition followed by Mukia maderaspatana (53%). Cardiospermum halicacabum has shown only 42.40% activity, whereas Delonix elata has shown only 14% activity. In the case of proteinase inhibition assay, Mukia maderaspatana at a concentration of 10 mg/ml has exhibited 74% inhibition of proteinase followed by Cardiospermum halicacabum 58%, Erythrina indica 38% and Delonix elata 30%. Among the four plants selected, except Delonix elata all the other three plants have revealed remarkable anti-inflammatory activity.


Cite this article:
K. Kousalya, T. Priya, P. Venkatalakshmi. Studies on the Anti-inflammatory potential of selected medicinal plants in vitro. Research J. Pharm. and Tech. 2020; 13(7): 3147-3150. doi: 10.5958/0974-360X.2020.00556.9


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