Author(s): Susmita Basak, K Ishwar Bhat

Email(s): bhatishwark@nitte.edu.in

DOI: 10.5958/0974-360X.2020.00473.4   

Address: Susmita Basak, K Ishwar Bhat*
Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, NITTE (Deemed to be University), Paneer, Deralakatte- 575018, Mangalore, Karnataka, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 6,     Year - 2020


ABSTRACT:
A series of (1E, 3E)-1-[2-(4-chlorophenyl)hydrazinylidene]-4-phenylbut-3-en-2-one(SC1-SC7) has been successfully synthesized from (1E)-1-(2-phenylhydrazinylidene) propan-2-one by condensation reaction in the presence of 20% NaOH as base catalyst. All the compounds were characterized by IR spectroscopy and confirmed by 1H NMR, Mass spectroscopy and elemental analysis. All the compounds have been screened for their antioxidant activity. Most of the compounds showed promising activity and can be used as a potential antioxidant drugs.


Cite this article:
Susmita Basak, K Ishwar Bhat. Synthesis, Characterization and Anti-oxidant Activity of Novel Phenylhydrazine derivatives containing carbonyl group on β- carbon. Research J. Pharm. and Tech 2020; 13(6): 2661-2666. doi: 10.5958/0974-360X.2020.00473.4


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