Author(s): Anil B. Chidrawar, Rajkumar U. Pokalwar, Nitishkumar S. Kaminwar

Email(s): anilchidrawar74@gmail.com

DOI: 10.5958/0974-360X.2020.00472.2   

Address: Anil B. Chidrawar1*, Rajkumar U. Pokalwar1, Nitishkumar S. Kaminwar2
1P G Research Centre, Department of Chemistry, Degloor College, Degloor, S.R.T.M.U. Nanded, India – 431717.
2P G Department of Chemistry, L. B. S. College, Dharmabad, S.R.T.M.U. Nanded, India - 431717.
*Corresponding Author

Published In:   Volume - 13,      Issue - 6,     Year - 2020


ABSTRACT:
A mixture of Bis methylthio methylene malononitrile (BMMM), thiourea and aniline/4-chloro aniline/4-methoxy aniline/4-nitro aniline on reflux with dimethyl formamide solvent in presence of K2CO3 for 5-6 hours. The progress of the reaction was monitored by TLC. After completion of the reaction, the mixture was cooled to room temperature, washed with water gives 2,6-dihydro-2,6-diimino-4,8-bis (phenylamino) pyrimido [2,1-b] [1,3] thiazine-3,7-dicarbonitrile and its derivatives respectively. The synthesized compounds were characterized by elemental analysis and spectral data.


Cite this article:
Anil B. Chidrawar, Rajkumar U. Pokalwar, Nitishkumar S. Kaminwar. An effective multicomponent synthesis of 2,6-dihydro-2,6-diimino-4,8-bis (phenylamino) pyrimido [2,1-b] [1,3] thiazine-3,7-dicarbonitrile. Research J. Pharm. and Tech 2020; 13(6):2658-2660. doi: 10.5958/0974-360X.2020.00472.2


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