Author(s): Rohil S S, P R Kumar

Email(s): rohil016@gmail.com , pathangikumar70@gmail.com

DOI: 10.5958/0974-360X.2020.00442.4   

Address: Rohil S S, P R Kumar*
Department of Pharmacognosy, S.R.M. College of Pharmacy, SRMIST, Kattankulathur - 603203, District- Kancheepuram (T.N.) India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 5,     Year - 2020


ABSTRACT:
Xanthium indicum Koeing. (Family: Asteraceae) is a plant with high medicinal uses which is more commonly found in the areas of Northern America, Malaysia, China, Brazil and other warmer parts of India. Different types of diseases can be treated using this herb. Various extracts of the plant, leaves, root, flower, fruit can be used in the treatment of fungal infection, urticaria, arthritis, salivation, epilepsy, TB, snake bite, insect bite, lumbago, malaria, diarrhoea. The phytochemical action and pharmacological action are viewed under the various activity like anti-tussive, anti-cancer, anti-fungal, dermatitis, CNS depressant activity, diuretic effect, anti-oxidant, insecticidal, herbicidal and so on. Many pharmacological effects can be demonstrated by the presence of chemical constituents like sesquiterpene, glycoside, phenol, polysterol that are present all over the parts of plant of Xanthium indicum. Various action of plant was seen and it can be used against dangerous diseases. Even though the fruits have toxic effect it can be used for the treatment for several ailments.


Cite this article:
Rohil S S, P R Kumar. Xanthium indicum Koenig – A Review. Research J. Pharm. and Tech 2020; 13(5):2475-2479. doi: 10.5958/0974-360X.2020.00442.4


REFERENCE:
1.    Oudhia P. Phyto-sociological studies of rainy season wasteland weeds with special reference to Parthenium hysterophorus L. in Raipur (India) district. Asian J Microbiol Biotech Environ Sci 2001; 3:89-92.
2.    Oudhia P, Dixit A. Weeds in Ambimkapur region (Madhya Pradesh) and their traditional use. Weed News 1994; 1:19-21.
3.    Dharmananda S. Safety issues affecting Chinese herbs: The case of Xanthium. Institute for Tradional Medicine- European Branch, Vol. 1. 2003. p. 1-8.
4.    Caius JF. Medicinal and poisonous plants of India. Jodhpur (India): Scientific Publishers; 1986. p. 375-6.
5.    Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants. New Delhi: Council of Scientific and Industrial Research; 1945. p. 259.
6.    Martin T, Stair EL, Dawson L. Cocklebur poisoning in cattle. J Am Vet Med Assoc 1986; 189:562-3.
7.    Oelkers S, Oehme F. Cocklebur poisoning in swine (Xanthium). Bov Pract. 1982; 3:11-4.
8.    Burrows GE, Tyrl RJ, Rollins D, Thedford TR, Mcmurphy W, Edwards WC. Toxic plants of Oklahoma and the Southern Plains. Stillwater: Oklahoma State University; 1991.
9.    Stuart BP, Cole RJ, Gosser HS. Cocklebur (Xanthium indicum L. var. strumarium) intoxication in swine: Review and redefinition of the toxic principle. Vet Pathol 1981; 18:368-83.
10.    Goodwin MA, Mallinson ET, Brown J, Player EC, Latimer KS, Dale N, et al. Toxicological pathology of cockleburs (Xanthium spp) for broiler chickens. Avian Dis 1992; 36:444-6.
11.    Agharkar SP. Medicinal plants of Bombay presidency. Jodhpur (India): Scientific Publishers; 1991. p. 230.
12.    Singh VK, Govil JN and Gurdipsingh, Recent progress in medicinal plants, Ethano medicine and pharmacognosy, SCI, Technical Publishing LLC, USA, (2002); pp: 106.
13.    Nadkarni KM. Indian Materia Medica, Mumbai, Popular prakashan Priavte Ltd, (1954); pp:106
14.    Chopra RN, Nayar SL, Choora IC, Glossary of Indian medicinal plants, National institute of science communication, New Delhi 110012, India (1956); pp: 63.
15.    Ram. P. Rastogi, Compedium of Indian medicinal plants, Vol-2, (1970-79), pp:259.
16.    Warrier PK, Indian medicinal plants, Vol -2, Orient Longman Private limited, (1980); pp.316
17.    Yoganarasiman SN, Medicinal Plants of India, Vol-2, Tamilnadu, Regional Research Institute, Banglore,India, (1984); pp.187
18.    Khare CP (Ed), Indian Medicinal Plants an Illustrated Dictionary, B-1/211. Janakipuri and New Delhi-110058. (2000); pp: 243
19.    Matthew KM, The flora of Tamilnadu Carnatic, St.Jospeph college series, Thiruchirapalli 620002,India Vol-3, p.g:1258
20.    Easu K, Jojn and sons, Plant Anatomy, Newyork, p.g: 767.
21.    Gamble. J S, Flora of old Precidency college old Madras, Botanical survey of India,Culcutta,Vol-I,II,III (1935).
22.    Henry AN, Kumari GR and Chitra V, Flora of Tamilnadu, Botanical Survey of India, Southern Circle, Coimbatore, India (1987); p.g:258.
23.    Willaman JJ, Li HL. Alkaloids bearing plants and their contained alkaloids, 1957-1968. Lloydia 1970; 33:268.
24.    Malik MS, Sangwan NK, Dhindsa KS. Xanthanolides from Xanthium indicum. Phytochemistry. 1992; 32(1): 206-207.
25.    Marco JA, Sanz-cervera JF, Cerral J, Carda M, Jakupovic J. Xanthanolides from Xanthium: Absolute configuration of Xanthanol, Isoxanthanol and their C-4 epimers. Phytochemistry. 1993; 24(6): 1569-1576.
26.    Winters TE, Geissman TA, Safir D. Sesquiterpene lactones of Xanthium species xanthanol and isoxanthanol and correlation of xanthinin with invalibin. J Org Chem 1969; 34:153.
27.    Minato H, Horibe I. Studies on sesquiterpenoids part XI, structure and stereochemistry of Xanthumin, a stereoisomer of Xanthinin. J Chem Soc 1965; Dec.7009-17.
28.    Molina-Torres J, Martinez ML. Tocopherols and leaf age in Xanthium indicum L. New Phytol 1991;118:95-9.
29.    Qin L, Han T, Li H, Zhang Q, Zheng H. A new thiazinedione from Xanthium indicum. Fitoterapia 2006; 77:245-6.
30.    Macleod JK, Moeller PD, Franke FP. Two toxic kaurene glycosides from the burrs of Xanthium pungens. J Nat Prod 1990; 53:451-5.
31.    Roussakis H, Chinou CI, Vayas CJ. Cytotoxic activity of Xanthatin and the crude extracts of Xanthium indicum. Planta Med 1994; 60:473-4.
32.    Mahmoud AA. Xanthanolide and Xanthane epoxide derivatives from Xanthium indicum. Planta Med 1998; 64:724-7.
33.    Ahmed A, Mahmoud A, El-Gamal A. A xanthanolide diol and a dimeric xanthanolide from Xanthium species. Planta Med 1999; 65:470-2.
34.    Ma Y, Huang M, Hsu F, Chang H. Thiazinedione from Xanthium indicum. Phytochemistry 1998; 48:1083-5.
35.    Kadioglu I. Effects of hearleaf cocklebur (Xanthium indicum L.) extract on some crops and weeds. Asian J Plant Sci 2004; 3:696-700.
36.    Han T, Li H.L., Zhang QY., Zheng HC., Qin LP. New Thiazinediones and other components from Xanthium indicum L. Chemistry of Natural Compounds. 2006; 42:567-70.
37.    Srivastava RC, Krishnamurthy RS, Athawale CR. Oil from the seed of gokhru (Xanthium indicum Linn). J Sci Industry Res 1950;9B:282.
38.    Bhakuni DS, Dhar ML, Dhar MM, Dhawan BN, Gupta B, Srimal RC. Screening of Indian plants for biological activity, part III. Indian J Exp. Biol. 1971; 9:91-102.
39.    CriagJr JC, Mole ML, Billets S, EI-Feraly F. Isolation and Identification of Hypoglycemic agent, Carboxyatracrylate, from Xanthium indicum. Phytochemistry. 1976; 15(7), 1178.
40.    Bisht NPS, Singh R. Chemical Investigation of the leaves of Xanthium indicum L. Journal of Indian Chemistry Society. 1977; 4:797-798.
41.    Bisht NPS, Singh R. Chemical Investigation of the leaves of Xanthium indicum L. Journal of Indian Chemistry Society. 1978; 55:707-708.
42.    Mondal AK, Parui S, Mandal S. Analysis of the amino acid content in pollen of nine Asteraceae species of known allergenic activity. Ann Agric Environ Med 1998; 5:17-20.
43.    Bhargava PP, Deshpande SS, Haksar CN. Oil from seed of Xanthium indicum. Indian Oil Soap J 1960-61; 61:105, 245.
44.    Dong KK, Chang KS, Dong WB, Yeon SK, Min-Suk Y, He KK. Identification and biological characteristics of an antifungal compound extracted from Cocklebur (Xanthium indicum) against Phytophthora drechsleri. The Plant Pathology J. 2002; 18:288-92.
45.    Mandal SC, Boominathan R, Devi BP, Panda S. Studies on antitussive activity of Xanthium indicum L. extract. ISHS Acta Horticulturae 678: III WOCMAP congress on Medicinal and Aromatic Plants- vol.4: Targeted Screening of Medicinal and Aromatic Plants, Economics and law 2005;678:149-52.
46.    Bisht NPS, Singh R. Chemical Investigation of the leaves of Xanthium indicum L. Journal of Indian Chemistry Society. 1978; 55:707-708.
47.    Kishore N, Dubey NK, Tripathi RD, Singh SK. Fungitoxicity of the leaf extracts of some higher plants against Fusarium Moniliforme. National Academy Science Letters 1982; 5:9-10.
48.    Amerjothy S, Ezhilarasi R, Shanmugakumar SD. Antimicrobial assay of the leaf extracts of Xanthium indicum Koen. Pharmacognosy Magazine: Short Communication. 2007. 11:197.
49.    Ma C, Kully M, Khan JK, Hattoric M, Daneshtalaba M. Synthesis of chlorogenic acid derivatives with promising antifungal activity. Bioorg Med Chem 2007; 15:6830-3.
50.    Menon GS, Kuchroo K, Dasgupta D. Interaction of microtubules with active principles of Xanthium indicum. Physiol Chem Phys Med NMR 2001; 33:153-62.
51.    Mandal SC, Dhara AK, Ashok Kumar CK, Maiti BC. Neuropharmacological activity of Xanthium indicum extract. J Herbs Spices Med Plants 2001; 8:69-77.
52.    Rastogi RP, Mehrotra BN. Compendium of Indian medicinal plant.CDRI Lucknow and NISC, New Delhi. 1960-1969; 1:437.
53.    Talakal TS, Dwivedi SK, Sharma SR. Invitro and invivo antitrypanosomal activity of Xanthium indicum leaves. J Ethnopharmacol 1995; 49:141-5.
54.    Tran QL, Tezuka Y, Veda J, Nguyen NT, Maruyama Y, Begum K, et al. Invitro antipalsmodial activity of antimalarial medicinal plants used in Vietnamese traditional medicine. J Ethnopharmacol 2003; 86:249-52.
55.    Aswathy, Balasankar Karavadi, Nisha H. Homology Modeling and Docking Studies to Identify the Targets in Pancreatic Cancer. Research J. Pharm. and Tech. 2017; 10(7): 2032-2040.
56.    Nisha H, Balasankar Karavadi, Aswathy. Computational Analysis to Identify the Drug Targets and their Lead Molecules in Pancreatic Cancer. Research J. Pharm. and Tech. 2017; 10(6): 1708-1716.
57.    Dra Gladys María Díaz García, Dra. María del Carmen León Padilla Lic, Eldris Iglesias Huerta. Evaluacion del efecto genotoxico del xhantium strumarium L. (Guisazo de caballo). Rev Cubana Plant Med 2004; 9:27-32.
58.    Dra. Lesly Jiménez Nieves, Dra. María del Carmen León Padilla, Dr. Reinaldo Herrera Rodríguez, Lic. Gastón García Simón y Dr. José Luis Cadenas Freixas. Efecto diuretico del Xanthium indicum L. (guizazo de caballo). Rev Cubana Plant Med 1999;1: 22-5.
59.    Hong SH, Jeong HJ, Kim HM. Inhibitory effects of Xanthii fructus extract on mast cell mediated allergic reaction in murine model. J Ethnopharmacol 2003; 88:229-34.
60.    S.B. Prabha, Mohini Rao, M. R. Ramesh Kumar. Evaluation of in vitro Antioxidant, Antibacterial and Anticancer activities of leaf extracts of Cleome rutidosperma. Research J. Pharm. and Tech. 2017; 10(8): 2492-2496.
61.    Venkatesh Kamath, Aravinda Pai, Rohith Raj. In Silico approach for the Rational Design of Tankyrase I Inhibitors–A Case Study on Flavone based Anticancer Leads. Research J. Pharm. and Tech 2018; 11(10): 4511-4514..
62.    Bark KM, Heo EP, Han KD, et al. Evaluation of phototoxic potential of plants used in oriental medicine. J Ethnopharmacol 2010;127:11-8.
63.    Cetinsoy S, Tamer A, Aydemir M. Investigations on repellent and insecticidal effects of Xanthium indicum L. on Colorado potato beetle leptinotrasa decemlineata say (Col: Chrysomelidae). Traditional J Agric Forestry 998;22:543-52.
64.    Harada AK, Sakata Ina H. Isolation and identification of xanthatin as an antiattaching repellent against Blue mussel. J Agric Biol Chem 1985;49:1887-8.
65.    Pasricha JS, Bhaumik P, Agarwal A. A high rate of cross sensitivity between P. Hyst erophorus and in Indian patients with contact dermatitis, Xanthium indicum. Indian J Dermatol Venereol Leprol 1990;56:319-21.
66.    Raghad Dhyea Abdul Jalill. Chemical Analysis and Anticancer effects of Juniperus polycarpos and Oak Gall plants extracts. Research J. Pharm. and Tech 2018; 11(6): 2372-2387
67.    Arvindganth. R, Anupriya K.V., Kathiravan. G. Enhancement of Anticancer Drug Annona muricata Against HT-29 Cell Line using Silver Nano Particles. Research J. Pharm. and Tech. 2017; 10(2): 529-532.
68.    Zhao, Y.; Yang, H.; Zheng, Y.B.;Wong, Y.O.; Leung, P.C. The Effects of Fructus Xanthii Extract on Cytokine Release from Human Mast Cell Line (HMC-1) and Peripheral Blood Mononuclear Cells. Immuno pharmacol. Immuno toxicol. 2008, 30, 543–552.
69.    Yan, G.H.; Jin, G.Y.; Li, G.Z.; Cui, C.A.; Quan, G.H.; Jin, D.S.; Jin, D.Z. The possible mechanism of inhibitory effect of Xanthium indicum on mast cells activated by compound 48/80. Prog. Anat. Sci. 2010, 16, 164–166.
70.    Peng,W.; Ming, Q.L.; Han, P.; Zhang, Q.Y.; Jiang, Y.P.; Zheng, C.J.; Han, Y.; Qin, L.P. Anti-allergic rhinitis effect of caffeoylxanthiazonoside isolated from fruits of Xanthium indicum L. in rodent animals. Phytomedicine 2014, 21, 824–829.
71.    Sridharamurthy, N.B.; Yogananda, R.; Srinivas, U. In-vitro Antioxidant and Antilipidemic Activities of Xanthium indicum L. Curr. Trends Biotechnol. Pharm. 2011, 5, 1362–1371.
72.    Li, X.M.; Yang, M.X.; Li, Z.P.; Xue, M.; ShangGuan, Z.S.; Ou, Z.M.; Liu, M.; Liu, S.H.; Yang, S.Y.; Li, X.J. Fructus xanthii improves lipid homeostasis in the epididymal adipose tissue of rats fed a high-fat diet. Mol. Med. Rep. 2016, 13; 787–795.
73.    Mukesh Kumar D. J., Sonia K., Madhan R., Selvakumar K., Kalaichelvan P.T. Antiyeast, Antioxidant and Anticancer Activity of Tribulus terrestris Linn and Bougainvillea spectabilis Linn. Research J. Pharm. and Tech. 4(9): Sept. 2011;1483-1489.
74.    Swarnalatha, Y. Isolation of Flavonoids and their Anticancer Activity from Sphaeranthus amaranthoides in A549 Cell Line. Research J. Pharm. and Tech. 8(4): April, 2015; Page 462-467
75.    Li, T.X.; Shen, J.Y.; Li, M.; Wang, G.R. Effects of Fructus Xanthii on Blood Glucose and Lipid in Diabetic Mice before and after Processing. Lishizhen Med. Mater. Med. Res. 2017, 28, 608–609.
76.    Liu, Y.; Wu, Z.M.; Lan, P. Experimental Study on Effect of Fructus Xanthii Extract on Duck Hepatitis B Virus. Lishizhen Med. Mater. Med. Res. 2009, 20;1776–1777.
77.    Shi, Y.S.; Liu, Y.B.; Ma, S.G.; Li, Y.; Qu, J.; Li, L.; Yuan, S.P.; Hou, Q.; Li, Y.H.; Jiang, J.D.; et al. Bioactive Sesquiterpenes and Lignans from the Fruits of Xanthium sibiricum. J. Nat. Prod. 2015, 78; 1526–1535.
78.    Lin, B., et al., Anti-arthritic activity of Xanthium indicum L. extract on complete Freund ׳s adjuvant induced arthrit is in rats. Journal of Ethnopharmacology, 2014. 155(1): p. 248-255
79.    John. D. Milton, M. Alvin Jose. Anticancer Activity of Ethyl Acetate Root Extract of Xanthium strumarium Linn. in N-Nitroso N-Methyl Urea Induced Mammary Carcinoma in Female Sprague-Dawley Rats. Research J. Pharm. and Tech 2016; 9(8):1115-1118.
80.    L. Krishnasamy, M. Masilamani Selvam, Bharathi Ravikrishnan. Anticancer property of Colchicine isolated from Indigofera aspalathoids. Research J. Pharm. and Tech. 2016; 9(4): 386-390.

Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): Vishal Vilas Shah, Nutan Dhanpal Shah, Prasad Vasantrao Patrekar

DOI: Not Available         Access: Open Access Read More

Author(s): Muhammad Hamdan, Noorhamdani AS, Masruroh Rahayu, Mohammmad Hasan Machfoed

DOI: 10.5958/0974-360X.2019.01020.5         Access: Open Access Read More

Author(s): Niha Naveed, Karthikeyan Murthykumar, Subasree Soundarajan, Sripradha Srinivasan

DOI: Not Available         Access: Open Access Read More

Author(s): Koushika Das, Pranit Krishna, Avipsha Sarkar, Shanmuga Sundari Ilangovan, Shampa Sen

DOI: 10.5958/0974-360X.2017.00267.0         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Rekha Rajendran, R Hemachander, T Ezhilarasan, C Keerthana, DL Saroja, KV Saichand, Mohamed Gasim Abdullah

DOI: Not Available         Access: Open Access Read More

Author(s): A. Julius, Ramachandran Vedasendiyar, Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, V. Saravanan

DOI: 10.5958/0974-360X.2017.00062.2         Access: Open Access Read More

Author(s): Avinash Bhagwat, Suhas M Kakade, Chirag V Naval, Mukesh Tilker, Ravindra M Walture, Sagar A Adichwal and Atul P Chaudhari

DOI: Not Available         Access: Open Access Read More

Author(s): Kousalya M., Geetha P., Jesuraja A., Vinoth Kumar M

DOI: 10.5958/0974-360X.2017.00014.2         Access: Open Access Read More

Author(s): Hayat M. Mukhtar, Vandna Kalsi

DOI: 10.5958/0974-360X.2018.00395.5         Access: Open Access Read More

Author(s): Pooja Thakur, Chirag Chopra, Daljeet Singh Dhanjal, Reena Singh Chopra

DOI: 10.5958/0974-360X.2017.00466.8         Access: Open Access Read More

Author(s): Som K. Madhvi, Manik Sharma, Javaid Iqbal, Mohd Younis

DOI: 10.5958/0974-360X.2019.00785.6         Access: Open Access Read More

Author(s): Mahanthesh M.C., Girendra Gautam, Jalalpure S.S.

DOI: 10.5958/0974-360X.2017.00250.5         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags