Author(s):
A. M. Maksatova, G. S. Akhmetova, U. M. Datkhayev, M. T. Omyrzakov, K. D. Praliyev, S. A. Ross, T. M. Seilkhanov, O. T. Seilkhanov
Email(s):
gulgakhmet@mail.ru
DOI:
10.5958/0974-360X.2020.00407.2 
Address:
A. M. Maksatova1, G. S. Akhmetova2, U. M. Datkhayev1, M. T. Omyrzakov3, K. D. Praliyev2, S. A. Ross4, T. M. Seilkhanov5, O. T. Seilkhanov5
1Asfendiyarov Kazakh National Medical University, 050000, Almaty, Kazakhstan.
2Institute of Chemical Sciences named after A.B. Bekturov, 050010, Almaty, Kazakhstan.
3GxP Company LLP, 050059, Almaty, Kazakhstan.
4University of Mississippi, 38677, Missisipi, USA.
5Sh. Ualikhanov Kokshetau State University, 202000, Kokshetau, Kazakhstan.
*Corresponding Author
Published In:
Volume - 13,
Issue - 5,
Year - 2020
ABSTRACT:
P-fluorine, m-fluorine,o-fluorinebenzoates of 1-propyl-4-hydroxypiperidine and 1-benzyl-4-hydroxypiperidine p-fluorobenzoate have been synthesized, which showed local anesthetic activity of varying degrees. Fluorobenzoic esters of secondary alcohols cause deep and prolonged anesthesia, the introduction of fluorine leads to local anesthetics with varying degrees of effectiveness.
Cite this article:
A. M. Maksatova, G. S. Akhmetova, U. M. Datkhayev, M. T. Omyrzakov, K. D. Praliyev, S. A. Ross, T. M. Seilkhanov, O. T. Seilkhanov. Biological Active Fluorobenzoates of Piperidine Range. Research J. Pharm. and Tech 2020; 13(5): 2261-2265. doi: 10.5958/0974-360X.2020.00407.2
Cite(Electronic):
A. M. Maksatova, G. S. Akhmetova, U. M. Datkhayev, M. T. Omyrzakov, K. D. Praliyev, S. A. Ross, T. M. Seilkhanov, O. T. Seilkhanov. Biological Active Fluorobenzoates of Piperidine Range. Research J. Pharm. and Tech 2020; 13(5): 2261-2265. doi: 10.5958/0974-360X.2020.00407.2 Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-5-37
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