Author(s): Jannathul Firdous, Norain Ab. Latif, Resni Mona, Rehanna Mansor, Noorzaid Muhamad

Email(s): jannathul.firdous@unikl.edu.my

DOI: 10.5958/0974-360X.2020.00365.0   

Address: Jannathul Firdous*, Norain Ab. Latif, Resni Mona, Rehanna Mansor, Noorzaid Muhamad
Cluster for Integrative Physiology and Molecular Medicine (CIPMM), Faculty of Medicine, Royal College of Medicine Perak, Universiti Kualalumpur, Jalan Greentown, 30450, Ipoh, Perak, Malaysia.
*Corresponding Author

Published In:   Volume - 13,      Issue - 4,     Year - 2020


ABSTRACT:
Medicinal plants are the important source of drugs that are used worldwide to meet the primary healthcare needs. Andrographis paniculata is one of the widely used effective medicinal plants in world. All parts of this plant are used to extract the potential phytochemicals but the aerial part of the plant contains medically important phytochemicals such as lactones, diterpenoids, diterpene glycosides, flavonoids, and flavonoid glycosides with various pharmacological activities. Endophytes are responsible to increase the production of plant bioactive compounds by its symbiotic association with the plants and favours the mechanism through metabolic interactions. The reasons for producing biologically active metabolites is due to its long term association with medicinal host plants, may improve/alter its natural bioactivity and obtain genetic details to produce such metabolites similar to the host. Hence this review focused on those properties and the phytochemical action of plant with bioactive compounds produced by endophytes isolated from such medicinal plants and its potential usefulness in human diseases.


Cite this article:
Jannathul Firdous, Norain Ab. Latif, Resni Mona, Rehanna Mansor, Noorzaid Muhamad. Andrographis paniculata and its Endophytes: A Review on their Pharmacological Activities. Research J. Pharm. and Tech 2020; 13(4): 2027-2030. doi: 10.5958/0974-360X.2020.00365.0


REFERENCES:
1.    Yu H, Zhang L, Li L, Zheng C, Guo L, Li W, et al. Recent developments and future prospects of antimicrobial metabolites produced by endophytes. Microbiol Res. 2010;165(6):437-49.
2.    Pan S-Y, Litscher G, Gao S-H, Zhou S, Yu Z-L, Chen H-Q, et al. Historical Perspective of Traditional Indigenous Medical Practices: The Current Renaissance and Conservation of Herbal Resources. 2014; 2014: 525340.
3.    Pan S-Y, Zhou S-F, Gao S-H, Yu Z-L, Zhang S-F, Tang M-K, et al. New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics. Evidence-based Complementary and Alternative Medicine: eCAM. 2013; 2013:627375.
4.    Akbar S. Andrographis paniculata: A Review of Pharmacological Activities and Clinical Effects. Altern Med Rev. 2011;16(1):66-77.
5.    Abd Kadir SL, Yaakob H, Mohamed Zulkifli R. Potential anti-dengue medicinal plants: a review. J Nat Med. 2013;67(4):677-89.
6.    Bhope SG, Kuber VV, Patil MJ, Ghosh VK. Validated HPTLC Method for the Quantitation of Andrographolide from Raw Material and Pharmaceutical Dosage Form. Asian J. Research Chem. 2009: 2(3): 314-317.
7.    Qadir MI, Abbas K, Tahir M, Irfan M, Raza Bukhari SF, Ahmed B, et al. Dengue fever: natural management. Pak J Pharm Sci. 2015;28(2):647-55.
8.    Navjot Kaur, Jeena Gupta. Comparison of phytochemical extraction solvents for Andrographis paniculata. Research J. Pharm. and Tech. 2017; 10(5): 1271-1276.
9.    Ekta Singh Chauhan, Kriti Sharma, Renu Bist. Andrographis paniculata: A Review of its Phytochemistry and Pharmacological Activities. Research J. Pharm. and Tech 2019; 12(2):891-900.
10.    Teixeira RR, Pereira WL, Oliveira AF, da Silva AM, de Oliveira AS, da Silva ML, et al. Natural products as source of potential dengue antivirals. Molecules. 2014;19(6):8151-76.
11.    Zhang X, Lin L, Zhu Z, Yang X, Wang Y, An Q. Colonization and modulation of host growth and metal uptake by endophytic bacteria of Sedum alfredii. Int J Phytoremediation. 2013;15(1):51-64.
12.    Alvin A, Miller KI, Neilan BA. Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds. Microbiol Res. 2014;169(7-8):483-95.
13.    Shoba Sundaramoorthy, Shylaja Gunasekaran, Uma Anitha, Sathiavelu Arunachalam, Mythili Sathiavelu. Endophytes for Antimicrobial Activity- A Review. Research J. Pharm. and Tech. 8(6): June, 2015; Page 742-748.
14.    Strobel G, Daisy B, Castillo U, Harper J. Natural products from endophytic microorganisms. J Nat Prod. 2004;67(2):257-68.
15.    Ramanpreet Kaur, Mainam Anamika Devi, Pratibha Vyas. Endophytic Pseudomonas sp. TCA1 from Tinospora cordifolia Stem with Antagonistic and Plant growth-promoting Potential. Research J. Pharm. and Tech. 2017; 10(2): 456-460.
16.    Jayakumar T, Hsieh C-Y, Lee J-J, Sheu J-R. Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide. Evidence-based complementary and alternative medicine: eCAM. 2013; 846740-.
17.    Maiti K, Mukherjee K, Murugan V, Saha BP, Mukherjee PK. Enhancing bioavailability and hepatoprotective activity of andrographolide from Andrographis paniculata, a well-known medicinal food, through its herbosome. J Sci Food Agric. 2010;90(1):43-51.
18.    Handa SS, Sharma A. Hepatoprotective activity of andrographolide against galactosamine and paracetamol intoxication in rats. Indian J Med Res. 1990;92:284-92.
19.    Puri SK, Habbu PV, Kulkarni PV and Kulkarni VH. Hepatoprotective activity of fungal endophytic fractions of Andrographis paniculata (burm. F.) Wall nees. leaves in Paracetamol and ethanol induced hepatotoxicity. Int J Pharm Sci and Res 2019; 10(1): 97-107.
20.    Shylaja Gunasekaran, Shoba Sundaramoorthy, Uma Anitha, Mythili Sathiavelu, Sathiavelu Arunachalam. Endophytic Fungi with Antioxidant Activity- A Review. Research J. Pharm. and Tech. 8(6): June, 2015; Page 731-737.
21.    Kurzawa M, Filipiak-Szok A, Klodzinska E, Szlyk E. Determination of phytochemicals, antioxidant activity and total phenolic content in Andrographis paniculata using chromatographic methods. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;995-996:101-6.
22.    Mamatha A. Brine Shrimp Lethality Test of Andrographis paniculata. Research J. Pharm. and Tech. 7(7): July 2014 Page 743-745.
23.    K. Puri S, Habbu P, V. Kulkarni P, H. Kulkarni V. Characterization, in vitro antioxidant and hepatoprotective activity of fungal endophytic extracts of andrographis paniculata leaves in ccl4 induced hepatotoxicity. International Journal of Pharmacy and Pharmaceutical Sciences. 2019; 11(1): 44-54.
24.    Singh S, Mehta A, Baweja S, Ahirwal L, Mehta P. Anticancer Activity of Andrographis paniculata and Silybum marianum on Five Human Cancer Cell Lines. Journal of Pharmacology and Toxicology. 2013; 8(1): 42-8.
25.    Peng T, Hu M, Wu TT, Zhang C, Chen Z, Huang S, et al. Andrographolide suppresses proliferation of nasopharyngeal carcinoma cells via attenuating NF-kappaB pathway. Biomed Res Int. 2015; 2015:735056.
26.    Wibudi A, Kiranadi B, Manalu W, winarto A, Suyono S. The traditional plant, Andrographis paniculata (Sambiloto), exhibits insulin-releasing actions in vitro. Acta Med Indones. 2008; 40(2):63-8.
27.    Nugroho AE, Andrie M, Warditiani NK, Siswanto E, Pramono S, Lukitaningsih E. Antidiabetic and antihiperlipidemic effect of Andrographis paniculata (Burm. f.) Nees and andrographolide in high-fructose-fat-fed rats. Indian Journal of Pharmacology. 2012;44(3):377-81.
28.    Edward J, Dompeipen, Yoice Srikandace, Wahyudi Priyono, Herry Cahyana and Partomuan. Potential endophytic microbes selection for anti-diabetic bioactive compounds production. Asian Journal of Biochemistry. 2011; 6(2): 465-471.
29.    Panossian A, Wikman G. Efficacy of Andrographis paniculata in Upper Respiratory Tract Infectious Diseases and the Mechanism of Action. Evidence and Rationale Based Research on Chinese Drugs. 2013. 137-79.
30.    Chen J-X, Xue H-J, Ye W-C, Fang B-H, Liu Y-H, Yuan S-H, et al. Activity of Andrographolide and Its Derivatives against Influenza Virus in Vivo and in Vitro. Biological and Pharmaceutical Bulletin. 2009;32(8):1385-91.
31.    Hu XY, Wu RH, Logue M, Blondel C, Lai LYW, Stuart B, et al. Andrographis paniculata (Chuan Xin Lian) for symptomatic relief of acute respiratory tract infections in adults and children: A systematic review and meta-analysis. PLoS One. 2017;12(8):e0181780.
32.    Raj K iwari, R Pandey, S S Shukla, Prashant Tiwari, H Shah. Antibacterial Activity of Aerial Part of Andrographis paniculata. Res. J. Pharmacognosy and Phytochem. 2014; 6(3): 122-125.
33.    R. Nancy Immaculate Mary, N. Banu. Antiquorum Sensing Potential of Andrographolide from Andrographis paniculata in Vibrio harveyi. Research J. Pharm. and Tech. 2017; 10(2): 449-452.
34.    Roy S, Yasmin S, Ghosh S, Bhattacharya S, Banerjee D. Anti-Infective Metabolites of a Newly Isolated Bacillus thuringiensis KL1 Associated with Kalmegh (Andrographis paniculata Nees.), a Traditional Medicinal Herb. Microbiology Insights. 2016; 9:1-7.

Recomonded Articles:

Author(s): Koushika Das, Pranit Krishna, Avipsha Sarkar, Shanmuga Sundari Ilangovan, Shampa Sen

DOI: 10.5958/0974-360X.2017.00267.0         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): A. Julius, Ramachandran Vedasendiyar, Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, V. Saravanan

DOI: 10.5958/0974-360X.2017.00062.2         Access: Open Access Read More

Author(s): Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M

DOI: 0.5958/0974-360X.2016.00047.0         Access: Open Access Read More

Author(s): Kousalya M., Geetha P., Jesuraja A., Vinoth Kumar M

DOI: 10.5958/0974-360X.2017.00014.2         Access: Open Access Read More

Author(s): Avinash Bhagwat, Suhas M Kakade, Chirag V Naval, Mukesh Tilker, Ravindra M Walture, Sagar A Adichwal and Atul P Chaudhari

DOI: Not Available         Access: Open Access Read More

Author(s): Mahanthesh M.C., Girendra Gautam, Jalalpure S.S.

DOI: 10.5958/0974-360X.2017.00250.5         Access: Open Access Read More

Author(s): Surendra Nath Pandeya, Rajeev Kumar, Arun Kumar, Ashish Kumar Pathak

DOI: Not Available         Access: Open Access Read More

Author(s): Anket Sharma, Vinod Kumar, Parminder Kaur, Ashwani Kumar Thukral, Renu Bhardwaj

DOI: 10.5958/0974-360X.2015.00299.1         Access: Open Access Read More

Author(s): Mohammed Ehtesham Ur Rahman, Mohammed Abdul Haseeb, Mohammed Saleem, Abdul Naveed

DOI: Not Available         Access: Open Access Read More

Author(s): Pankaj Kumar, Jennifer Fernandes, Abhishek Kumar

DOI: 10.5958/0974-360X.2017.00023.3         Access: Open Access Read More

Author(s): Tarasankar Maity, Ayaz Ahmad, Nilanjan Pahari, Subarna Ganguli

DOI: Not Available         Access: Open Access Read More

Author(s): U.S MahadevaRao, Khamsah Suryati Mohd, Siti Zulaikha Bt Abd Halim, Masitah Bt Khamis

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 


Recent Articles




Tags