Author(s): Betsy Sunny, Dr. Manju Maria Mathews, Dhanish Joseph, Flowerlet Mathew, Junia George, Bimi Varghese

Email(s): betsysunnye@gmail.com

DOI: 10.5958/0974-360X.2020.00351.0   

Address: Betsy Sunny1*, Dr. Manju Maria Mathews2, Dhanish Joseph3, Flowerlet Mathew4, Junia George5, Bimi Varghese6
1,5,6Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala.
2Associate Professor, Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala.
3,4Assistant Professor, Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala.
*Corresponding Author

Published In:   Volume - 13,      Issue - 4,     Year - 2020


ABSTRACT:
Plants are an exemplary source of medicine and have been used in healthcare since time immemorial. They are an efficacious remedy for multiple ailments. Coccinia grandis belonging to family Cucurbitaceae is a reservoir of medicinal properties. It is being regarded as a universal panacea in Ayurvedic medicines. Extracts made from the various parts of the plant mainly leaf and fruit have significant analgesic, anti-inflammatory, antimicrobial, antidiabetic, antioxidant, hepatoprotective, anticancer, mutagenic activity, etc. in different animal models. Coccinia grandis contain copious amounts of phytoconstituents like flavonoids, saponins, glycosides, alkaloids, phenols, etc. which heavily contribute to the diverse pharmacological activities. In this study, the focus is given to Coccinia grandis as a better herbal substitute for synthetic counterparts in antihyperglycemic therapy.


Cite this article:
Betsy Sunny, Dr. Manju Maria Mathews, Dhanish Joseph, Flowerlet Mathew, Junia George, Bimi Varghese. Antihyperglycemic Status of Coccinia grandis: An Extensive Overview. Research J. Pharm. and Tech. 2020; 13(4):1949-1954. doi: 10.5958/0974-360X.2020.00351.0


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3.    Mohammed SI et al. In vivo antidiabetic and antioxidant activities of Coccinia grandis leaf extract against streptozotocin induced diabetes in experimental rats. Asian Pacific Journal of Tropical Disease. 2016 ; 6(4):298-304.
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