Author(s):
A. Sreedevi, G. Lakshmi Manasa, B. Divya, C. Shipa, K. Sai Sruthi
Email(s):
sridevitirupati@rediffmail.com
DOI:
10.5958/0974-360X.2020.01036.7
Address:
A. Sreedevi*, G. Lakshmi Manasa, B. Divya, C. Shipa, K. Sai Sruthi
Division of Pharmaceutical Chemistry, Institute of Pharmaceutical Technology, Sri Padmavathi Mahila Visvavidyalayam, Tirupati, Andhra Pradesh, India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 12,
Year - 2020
ABSTRACT:
The present study was aimed to synthesize nanoparticles using a facile environmentally benevolent green synthetic route. They were synthesized by reducing the silver ions present in the solution of silver nitrate (0.001M) with aqueous seed extract of Sorghum bicolor. The aqueous extract was subjected for preliminary phytochemical analysis according to standard methods. Characterization of silver nanoparticles was done by using UV, FTIR, SEM and TEM analysis. Further synthesized silver nano particles were screened for anti-bacterial activity at 50, 100, 150, 200µg/ml concentrations against two Gram positive bacteria (Staphylococcus aureus, Bacillus subtilis) and one Gram negative bacteria (Escherichia coli). The synthesized nanoparticles had shown highest antibacterial activity against Staphylococcus aureus and moderate anti-bacterial activity against Bacillus subtilis and Escherichia coli. Thus this study can be applied for rapid, cost effective and eco-friendly green synthesis of silver nanoparticles using seeds of Sorghum bicolor.
Cite this article:
A. Sreedevi, G. Lakshmi Manasa, B. Divya, C. Shipa, K. Sai Sruthi. Eco-friendly Synthesis of Silver Nanoparticles using seeds of Sorghum bicolor. Research J. Pharm. and Tech. 2020; 13(12):5935-5938. doi: 10.5958/0974-360X.2020.01036.7
Cite(Electronic):
A. Sreedevi, G. Lakshmi Manasa, B. Divya, C. Shipa, K. Sai Sruthi. Eco-friendly Synthesis of Silver Nanoparticles using seeds of Sorghum bicolor. Research J. Pharm. and Tech. 2020; 13(12):5935-5938. doi: 10.5958/0974-360X.2020.01036.7 Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-12-51
REFERENCES:
1. Bhushan B. Introduction to Nanotechnology, Springer Handbook of Nanotechnology 2010; pp.1-12.
2. Zainal A, Rosiyah Y, Shamala D et al. Green Synthesis of Silver Nanoparticles Using Apple Extract and Its Antibacterial Properties. Advances in Materials Science and Engineering. 2016; 1-6.
3. Rai M, Yadav A, Gade A. Silver nanoparticles as a new generation of antimicrobials. Biotechnology Advances. 2009; 27(1): 76-83.
4. Caswell KK, Bender CM, Murphy CJ. Seedless, surfactantless wet chemical synthesis of silver nanowires. Nano Letters. 2003; 3(5): 667-669.
5. Yin Z,. Li Z. Zhong B. GatesYet al. Synthesis and characterization of stable aqueous dispersions of silver nanoparticles through the Tollens process. Journal of Materials Chemistry. 2002; 12(3): 522527.
6. Khanna PK, Singh N, Charan S, Subbarao VVS et al. Synthesis and characterization of Ag/PVA nanocomposite by chemical reduction method. Materials Chemistry and Physics. 2005; 93(1): 117-121.
7. Wiley B, Herricks T, Sun Y, Xia Y. Polyol synthesis of silver nanoparticles: use of chloride and oxygen to promote the formation of single-crystal, truncated cubes and tetrahedrons. Nano Letters. 2004; 4(9): 1733-1739.
8. Singh A . Green synthesis of silver nanoparticles using Argemone mexicana leaf extract and evaluation of their antimicrobial activities. Digest Journal of Nanomaterials and Biostructures.2010; 5(2): 483-489.
9. Mahmoud WM, Abdelmoneim TS, Elazzazy AM. The Impact of Silver Nanoparticles Produced by Bacillus pumilus As Antimicrobial and Nematicide. Front Microbiol. 2016;7:1746.
10. Shubha HS, Hiremath RS. Evaluation of antimicrobial activity of Rasaka Bhasma. Ayu. 2010;31(2):260–262.
11. Abiola. Green synthesis of silver nanoparticles using terrestrial fern (Glechinia pectinata (wild) persl.) characterization and antimicrobial studies, Heliyon, 2019, 5(4):e01543.
12. Siddiqi KS, Husen A, Rao RAK. A review on biosynthesis of silver nanoparticles and their biocidal properties. J Nanobiotechnology. 2018;16(1):14.
13. Agnihotri S, Mukherji S, Mukherji S. Size-controlled silver nanoparticles synthesized over the range 5–100 Nm using the same protocol and their antibacterial efficacy. RSC Adv. 2014; 4:3974–3983.