Author(s): A. A. Abdualiyeva, N. N. Akhmetsadykov, A. Valdovska, B. U. Shanbaev

Email(s): asem.a.86@mail.ru

DOI: 10.5958/0974-360X.2020.01035.5   

Address: A. A. Abdualiyeva1, N. N. Akhmetsadykov2, A. Valdovska3, B. U. Shanbaev2
1Kazakh National Agrarian University, Kazakhstan.
2Scientific-Production Enterprise "Antigen", Kazakhstan.
3Latvian Agricultural University, Latvia.
*Corresponding Author

Published In:   Volume - 13,      Issue - 12,     Year - 2020


ABSTRACT:
Developing an effective and high-quality vaccine is an important issue in rabies prevention. This article presents the results of the studies aimed at selecting the optimum parameters for the cultivation of the VN-21 finite cell line and the CVS-11 strain of the rabies virus. Such parameters as inoculated cell concentration, the optimal dose of infection with the virus, the time and methods of cultivation, and the choice of the inactivant and the adjuvant were chosen.


Cite this article:
A. A. Abdualiyeva, N. N. Akhmetsadykov, A. Valdovska, B. U. Shanbaev. Improving the Technology of obtaining an inactivated Antirabic vaccine from CVS-11 strain. Research J. Pharm. and Tech. 2020; 13(12):5929-5934. doi: 10.5958/0974-360X.2020.01035.5


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