Author(s): Ramesh Bhandari, C. S. Shastry, Sharad Chand, R. Anusha, Arun J., Dhruba Rana Chhetri, H. N. Girish

Email(s): sureechand193@gmail.com

DOI: 10.5958/0974-360X.2020.01008.2   

Address: Ramesh Bhandari, C. S. Shastry, Sharad Chand, R. Anusha, Arun J., Dhruba Rana Chhetri3, H. N. Girish
1Department of Pharmacy Practice, KLE College of Pharmacy (Constituent unit of KAHER), Nehrunagar, Belagavi-590010.
2Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Deralakatte, Mangaluru- 575 018, India.
3Department of Pharmacy Practice, TVM College of Pharmacy, Kappagal Road, Y. Nagesh Shastry Nagar, Ballari, Karnataka-583103, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 12,     Year - 2020


ABSTRACT:
Background: Dengue is a debilitating condition caused by a flavivirus. The female Aedes mosquito widely transmits this virus. The prevalence of mosquito-borne diseases like dengue and malaria is very high in the northern and southern parts of Karnataka. Objectives: This study aims to find the prevalence of dengue and its clinical occurrence in a tertiary care teaching hospital. Methodology: A prospective observational study was carried out in a tertiary care teaching hospital in a hospitalized patient diagnosed with dengue fever. Patients who satisfied the inclusion criteria were enrolled in the study. All the relevant data was collected in a specially designed data collection form. The data were analyzed by using computer tools like Microsoft Excel and SPSS software version 20.0. Results: In our study out of a total of 315 patients males were higher than female and the dengue was commonly prevalent in the age group of 15-30 years followed by 30-45 years. Fever (99.7%) and generalized body ache (GBA, 58.5%) were the most common clinical presentations. Ns1 antigen (67.61%) was found to be positive in the majority of patients. Blood hematocrit was elevated (26.63%) in most of the abnormal cases and white blood cell count (36.19%) and platelets (96%) counts were decreased. Platelet was found the most common laboratory parameter to get affected in dengue fever. Conclusion: The most common symptoms for dengue are concluded as fever, GBA, Headache and joint pain in our study. Blood hematocrit was elevated, but WBC and platelet counts were severely decreased. The prevalence was found higher in the monsoon season of September to November. All the patients enrolled in the study were counseled regarding diseases, and education was provided on various preventive measures.


Cite this article:
Ramesh Bhandari, C. S. Shastry, Sharad Chand, R. Anusha, Arun J., Dhruba Rana Chhetri, H. N. Girish. Clinical and Laboratory Aspects of Dengue Fever in Tertiary Care Hospital. Research J. Pharm. and Tech. 2020; 13(12):5783-5786. doi: 10.5958/0974-360X.2020.01008.2

Cite(Electronic):
Ramesh Bhandari, C. S. Shastry, Sharad Chand, R. Anusha, Arun J., Dhruba Rana Chhetri, H. N. Girish. Clinical and Laboratory Aspects of Dengue Fever in Tertiary Care Hospital. Research J. Pharm. and Tech. 2020; 13(12):5783-5786. doi: 10.5958/0974-360X.2020.01008.2   Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-12-23


REFERENCES:
1.    WHO, dengue: Guidelines for diagnosis, treatment, prevention, and control. Geneva: World Health Organization; 2009.
2.    Aarti Jain, Occurrence of dengue fever in tertiary care Hospitals. International journal of current microbiology and applied sciences, Feb 2017; 6(2):1085-1089.
3.    Devaleenal B, Shanthi S, Rajasekaran S, Mehendale S, Dengue fever in Saidapet health unit district in Tamil Nadu: Trends from 2004-2011. Clinical Epidemiology and Global Health, 3(2015):94-98.
4.    Reddy M.N, Dungdung R, Valliyott L, and Pilankatta R, Occurrence of concurrent infection with multiple serotypes of dengue viruses during 2013-2015 in Northern Kerela, India. Peer J, 2017, 10.7717/peerj.2970:1-16.
5.    Jagtap M.B, Sale L.S, Bhosale A.S, Sathe A, and Sathe T.V, Incidence of dengue and shifting trend to rural in Kolhapur district, India. Biological Forum-An international journal, 2009, 1(2):58-61.
6.    Govt. Of India (2008), Guidelines for Clinical Management of Dengue fever, Dengue Haemorrhagic Fever, and Dengue Shock Syndrome, Ministry of Health and Family Welfare, New Delhi.
7.    CDC Imported Dengue-- the United States, 1998 and 1998. Morb Mortal Wkly Rep. 2000;49:248-5.
8.    Khan Md. Y, Venkateshwarlu C, Sandeep N, Hari Krishna A. A study of clinical and laboratory profile of dengue fever in a tertiary care hospital, Nizamabad, Telangana State, India. International Journal of Contemporary Medical Research. 2016;3(8):2383-2387.
9.    Kyle JL, Harris E. Global spread and persistence of dengue. Annu Rev. Microbial. 2008;62:71-92.
10.    Malavige GN, Velathanthiri VG, Wije Wikrama ES, Fernando S, Jayaratne SD, Aaskov J, Seneviratne SL. A pattern of disease among adults hospitalized with Dengue infection. QJM. 2006;99;299-305.
11.    Seema A, Singh V, Kumar.S, Kumar A, Datta S.The Changing clinical spectrum of Dengue fever in the 2009 Epidemic in North India: A tertiary Teaching Hospital Based Study. Journal of clinical and Diagnostic Research. 2012;6:999-1002.
12.    Ritu Karoli, Jalees Fatima, Zeba Siddiqi, et al. Clinical Profile of Dengue infection at a Teaching Hospital in North India. J Infect Dev Ctries. 2012;6:551-554.
13.    Lepakshi G, N Padmaja, Rafiq Pasha H. A study of clinical profile of Adult patients with dengue fever. Indian Journal of Applied Research. 2015;5:820-823.
14.    Deshwal R, Md Ishaque Qusheshi, Raj Singh. Clinical and Laboratory Profile of Dengue fever. JAPI December 2015, Vol 63.

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