Wasim Khan, Vaseem Ahmad Ansari, Zeashan Hussain
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Wasim Khan1, Vaseem Ahmad Ansari2*, Zeashan Hussain3
1Research Scholar, Faculty of Pharmacy, Integral University, Lucknow, UP.
2Associate Professor (Jr.), Faculty of Pharmacy, Integral University, Lucknow, UP.
3Professor/Director, Mahatma Gandhi Institute of Pharmacy, Lucknow, UP.
Volume - 13,
Issue - 11,
Year - 2020
Ophthalmic drug delivery is one of the most enthusiastic and tough goal today encountered by formulation scientists. The anterior and posterior parts of eye are constituted by many barriers, which are responsible for the less efficacy of conventional drug delivery system like eye ointments, drops and suspensions. Since these formulations are not in reach of posterior segment of eye and only treat anterior segment, the diseases of posterior segment can be treated with intravenous, intravitreal or periocular route. In this situation, the objective of formulation scientists is to develop a new system for ocular drug delivery that permits localized release of the drug for prolonged period of time, to improve the therapeutic efficacy and patient compliance, and minimize side effects, thus SNEEDS comes into existence. It is drug delivery system is stable (thermodynamically and kinetically) under mild agitation followed by dilution of aqueous media such as GI fluid and it can from stable O/W Nanoemulsion having size of globules is less than 100nm. To prevent the interfacial tension and improving the dissolution as well as absorption rate of drug molecule NDDS is required. Novel Drug Delivery System can be used for parenteral, ophthalmic preparations, intranasal and cosmetic drug delivery system. And in this review description ofbarriers (need), components, formulation aspects, characterization of SNEDDS is explained.
Cite this article:
Wasim Khan, Vaseem Ahmad Ansari, Zeashan Hussain. Self-Nano Emulsifying Drug delivery system (SNEEDS) for Ocular Administration. Research J. Pharm. and Tech. 2020; 13(11):5576-5582. doi: 10.5958/0974-360X.2020.00973.7
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