Author(s): Bhavana Bhat, Sahana Pai, Manisha Panda, Aadrika, Kumari Anjali, Aswatha Ram H N, Aravinda Pai, Venkatesh Kamath B.

Email(s): vk82biochem@rediffmail.com

DOI: 10.5958/0974-360X.2020.00883.5   

Address: Bhavana Bhat1, Sahana Pai2, Manisha Panda3, Aadrika3, Kumari Anjali3, Aswatha Ram H N4 Aravinda Pai5, Venkatesh Kamath B.6*
1Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India – 576104.
2PG student, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India – 576104. 3UG students, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India – 576104.
4Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India – 576104.
5Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India – 576104.
6Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka,

Published In:   Volume - 13,      Issue - 10,     Year - 2020


ABSTRACT:
Magnetotactic bacteria (MTB) are also known as magnetic bacteria. They were discovered by the scientist Salvatore Bellini in 1965. These bacteria can produce nano sized bacterial magnetic particles under normal temperature and pressure. Bacterial magnetic particles are ultrafine magnetic particles having the diameter of 50-100 nm. They are produced by a genus of bacteria called Magnetospirillum magneticum. These magnetic structures act as compass needle permitting the bacteria to migrate through redox potential with Earth’s magnetic field. Therefore, they are called polyphyletic group of bacteria. Although this unique group of micro-organisms were discovered several decades ago, the mechanism and medical application of the magnetic particles have not been clarified yet. Currently, it has been claimed that these bacteria have been widely used in biochemistry, microbiology, mineralogy, limnology, biophysics and geology. But, there is a need to unravel the world of these magnificent organisms to learn about the mechanism of magnetism therapy in medical field. The present review article gives an insight on the application of magnetosomes in modern biological and medical sciences.


Cite this article:
Bhavana Bhat, Sahana Pai, Manisha Panda, Aadrika, Kumari Anjali, Aswatha Ram H N, Aravinda Pai, Venkatesh Kamath B. Isolation of Microbes possessing magnetosomes and their potential role in Drug delivery. Research J. Pharm. and Tech. 2020; 13(10):5042-5044. doi: 10.5958/0974-360X.2020.00883.5


REFERENCES:
1.    Richard B. F. The discovery of magnetotactic/magnetosensitive bacteria. Chinese Journal of Oceanology and Limnology. 2009; 27(1): 1-2.
2.    Bazylinski and Schübbe. Controlled biomineralization by and applications of magnetotactic bacteria. Adv Appl Microbiol. 2007; 62: 21-62
3.    Suleyman Dasdagand Hava Bektas. Magnetotactic Bacteria and their Application in Medicine, Journal of Physical Chemistry and J Biophysics.2014; 4(2): 1-5.
4.    Jogler C, Schüler D. Genomics, genetics, and cell biology of magnetosome formation Annu Rev Microbiol. 2009; 63:501-21.
5.    Syed Sajeed Ali, N.N. Vidhale. Bacterial Siderophore and their Application: A review. Int.J.Curr.Microbiol.App.Sci.2013; 2(12): 303-312.

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DOI: 10.5958/0974-360X 

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