Author(s): Suruj Kaushik, Trilochan Satapathy, Amit Roy, Pushpa Prasad Gupta, Prerna Purabiya

Email(s): surujkaushik59@gmail.com

DOI: 10.5958/0974-360X.2020.00087.6   

Address: Suruj Kaushik*, Trilochan Satapathy, Amit Roy, Pushpa Prasad Gupta, Prerna Purabiya
Department of Pharmacology, Columbia Institute of Pharmacy, Tekari, Raipur, Chhattisgarh-493111, India
*Corresponding Author

Published In:   Volume - 13,      Issue - 1,     Year - 2020


ABSTRACT:
Polycystic Ovarian Syndrome (PCOS) is the major cause of female infertility that affecting 5-10% of women of reproductive age (18-44 years). Many cases, the women do not find that they suffer from this syndrome until they try to get pregnant. The etiology includes the multiple fluid sacs or cysts grow in either or both ovaries where in some cases symptoms persist and others have no symptoms. The syndrome is characterized by chronic absence of ovulation as well as high levels of androgens. The major cause that contributes this syndrome includes mutation of one or more gene that causes hormonal imbalance, life style disturbance as well as environmental factors. Symptoms of PCOS include Infertility, hirsutism, menstrual irregularities, male pattern baldness, excessive hair growth on face, abnormal cholesterol or triglyceride levels etc. Treatment focuses on clinical improvement of patients suffered from the condition. The therapies include insulin sensitizing medications such as metformin that at present has gaining great interest. Use of metformin may reduce the risk of hyperinsulinism, type-2 diabetes, and metabolic syndrome. Other medications include oral contraceptives or anti-androgen medications also proved beneficial in some cases. Clomiphene Citrate was used in many cases alone or in combination for ovulation induction in oligomenorrheic women. In this review, we have tried to explore the beneficial use of non psychoactive Cannabidiol to reduce the stress and pain during the Polycystic Ovarian Syndrome.


Cite this article:
Suruj Kaushik, Trilochan Satapathy, Amit Roy, Pushpa Prasad Gupta, Prerna Purabiya. Endocannabinoid activation and polycystic ovary syndrome: A systematic review. Research J. Pharm. and Tech. 2020; 13(1):448-452. doi: 10.5958/0974-360X.2020.00087.6


Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): Amurdhavani. B.S

DOI: 10.5958/0974-360X.2016.00299.7         Access: Closed Access Read More

Author(s): G. Bhavani, R. Navaneethan

DOI: 10.5958/0974-360X.2017.00269.4         Access: Open Access Read More

Author(s): R. Narayana Charyulu, P. Parvathy Devi, Jobin Jose, A. Veena Shetty

DOI: Not Available         Access: Open Access Read More

Author(s): P.Maheshwari, D.Pavithra, Neethu.T.T, T.S. Shanmugarajan, P. Shanmugasundaram

DOI: 10.5958/0974-360X.2017.00011.7         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Sandeep D. S, Prashant Nayak, Jobin Jose, Rishal Relita M, Sumana D. R.

DOI: 10.5958/0974-360X.2017.00317.1         Access: Open Access Read More

Author(s): Vishal Vilas Shah, Nutan Dhanpal Shah, Prasad Vasantrao Patrekar

DOI: Not Available         Access: Open Access Read More

Author(s): Rahar Sandeep, Nagpal Navneet, Swami Gaurav, Arora Manisha, Bansal Suraj, Goyal Sandeep, Singla Shwali, Singh Preeti, Kapoor Reni

DOI: Not Available         Access: Open Access Read More

Author(s): Sonte Sushmitha, Sedimbi Revathi Priyanka, L. Mohan Krishna, M. Srinavasa Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Priya P. Munshi, D.S. Mohale, R. Akkalwar, A.V. Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): Siripurapu Sriram, Venkata Ravibabu Mandla, Chaithanya Sudha M, Saladi S.V. Subba Rao, Nagaveni Ch, Vani V., Gobinath P., Raj Kumar KVG., Jaydeep Lella, Sannidhi Krishna Praveen, Debjit Datta

DOI: 10.5958/0974-360X.2017.00078.6         Access: Open Access Read More

Author(s): P. Geetha, M. Kousalya, S. Geetha Lakshmi, R. Gopi.

DOI: 10.5958/0974-360X.2016.00046.9         Access: Open Access Read More

Author(s): Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M

DOI: 0.5958/0974-360X.2016.00047.0         Access: Open Access Read More

Author(s): G. Nithya Karpagam, Mahesh, Shanmugavel

DOI: 10.5958/0974-360X.2016.00179.7         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags