Author(s):
Mukthinuthalapati Mathrusri Annapurna, Sistla Mounica Pratyusha, Raghu Raj Naik
Email(s):
mannapurna.mukthinuthalapati@gitam.edu
DOI:
10.5958/0974-360X.2020.00055.4 
Address:
Mukthinuthalapati Mathrusri Annapurna*, Sistla Mounica Pratyusha, Raghu Raj Naik
Department of Pharmaceutical Analysis, GITAM Institute of Pharmacy,
GITAM (Deemed to be) University, Visakhapatnam-530045, India
*Corresponding Author
Published In:
Volume - 13,
Issue - 1,
Year - 2020
ABSTRACT:
Three new spectrophotometric methods have been developed for the simultaneous determination of combined dosage forms of Teneligliptin and Metformin tablets. Simultaneous equation method (Method A), Q-analysis (Method B) and First derivative (Method C) spectrophotometric methods were developed for the quantification of Teneligliptin and Metformin in sodium hydroxide. Linearity was observed 1-100 µg/ml and 1-35 µg/ml in Method A; 1-60 µg/ml and 1-35 µg/ml in both Method B and Method C for Teneligliptin and Metformin respectively. All the methods were validated as per ICH guidelines and applied for the simultaneous determination of Teneligliptin and Metformin in tablets.
Cite this article:
Mukthinuthalapati Mathrusri Annapurna, Sistla Mounica Pratyusha, Raghu Raj Naik. New validated spectrophotometric methods for the combined dosage form of Teneligliptin and Metformin. Research J. Pharm. and Tech. 2020; 13(1): 270-274 doi: 10.5958/0974-360X.2020.00055.4
Cite(Electronic):
Mukthinuthalapati Mathrusri Annapurna, Sistla Mounica Pratyusha, Raghu Raj Naik. New validated spectrophotometric methods for the combined dosage form of Teneligliptin and Metformin. Research J. Pharm. and Tech. 2020; 13(1): 270-274 doi: 10.5958/0974-360X.2020.00055.4 Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-1-55