Author(s):
Shanaz Banu, Josephine Leno Jenita, Manjula. D, K. B. Premakumari
Email(s):
shanaz2906@gmail.com
DOI:
10.5958/0974-360X.2020.00033.5 
Address:
Shanaz Banu1*, Josephine Leno Jenita2, Manjula. D2, K. B. Premakumari3
1Department of Pharmacognosy, Dayananda Sagar University, Bangalore- 560078, India.
2Department of Pharmaceutics, Dayananda Sagar University, Bangalore, India.
3Department of Pharmaceutical Analysis, Dayananda Sagar University, Bangalore, India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 1,
Year - 2020
ABSTRACT:
The present investigation was carried out to study the histological characters of the roots of the plant Barleria cristata Linn. Further the phytochemical studies on the methanolic extract of roots revealed the presence of alkaloids. Column chromatography of methanolic extract of Barleria cristata Linn. roots (MEBC) was carried out by using silica gel (60-120#) column chromatography. It was eluted by different solvents in their increasing order of polarity. Fraction No.11 was purified by fractional crystallization to yield 55mg of brown coloured amorphous powder of Compound-I which was characterized and confirmed as Ibogamine by TLC, melting point, Infrared Spectroscopy, 1H NMR, 13C NMR and Mass spectrometry. Ibogamine, an alkaloid was isolated from the roots of Barleria cristata Linn. roots.
Cite this article:
Shanaz Banu, Josephine Leno Jenita, Manjula. D, K. B. Premakumari. Pharmacognostical Studies and Isolation of an alkaloid from Barleria cristata Linn. roots. Research J. Pharm. and Tech. 2020; 13(1):163-167. doi: 10.5958/0974-360X.2020.00033.5
Cite(Electronic):
Shanaz Banu, Josephine Leno Jenita, Manjula. D, K. B. Premakumari. Pharmacognostical Studies and Isolation of an alkaloid from Barleria cristata Linn. roots. Research J. Pharm. and Tech. 2020; 13(1):163-167. doi: 10.5958/0974-360X.2020.00033.5 Available on: https://rjptonline.org/AbstractView.aspx?PID=2020-13-1-33