Author(s): Pooja Bedi, Goutam Pramanik, Tanay Pramanik


DOI: 10.5958/0974-360X.2020.00030.X   

Address: Pooja Bedi1, Goutam Pramanik2, Tanay Pramanik1, 3*
1Department of Chemistry, School of Chemical Engineering and Physical Science, Faculty of Technology and Sciences, Lovely Professional University, Phagwara, P.O. Box 144411, India.
2Institute of Organic Chemistry and Biochemistry of the CAS, Flemingovonam. 2, 16610 Prague 6, Czech Republic.
3Department of Chemistry, University of Engineering and Management, University Area, Action Area III, B/5, Newtown, Kolkata-700160
*Corresponding Author

Published In:   Volume - 13,      Issue - 1,     Year - 2020

Present research work demonstrates the use of garlic as natural biocatalyst for green synthesis of a series of Schiff bases which are an important class of pharmaceutically important compounds, employing p-toluidine and variety of aromatic aldehydes as reactants. The products were obtained with good percentage of yield by simply grinding the reactants together with pestle in a mortar in presence of a piece of garlic in a completely solvent free condition. The synthesized crude products were purified by recrystallization from hot ethanol to obtain pure Schiff bases which were characterized by melting point, FTIR, 1H-NMR and 13C-NMR. Through this work, a very simple, eco-friendly, effective, economic and new methodology is developed for synthesis of Schiff bases.

Cite this article:
Pooja Bedi, Goutam Pramanik, Tanay Pramanik. Garlic Catalyzed and Grindstone Assisted Solvent Free Green Synthesis of Pharmaceutically important Schiff Bases. Research J. Pharm. and Tech. 2020; 13(1): 152-156. doi: 10.5958/0974-360X.2020.00030.X

Recomonded Articles:

Author(s): Malarkodi Velraj, P. Jasmine Shiney, Biplab Paul, Rashmi. S, Nivethitha

DOI: 10.5958/0974-360X.2017.00006.3         Access: Open Access Read More

Author(s): Chandak BG, Sarpate RV, Chatterjee NR, Baheti KG

DOI: Not Available         Access: Open Access Read More

Author(s): A. Kaura, Lalit Sharma, V. J. Dhar

DOI: Not Available         Access: Open Access Read More

Author(s): B. R. Thorat, M. Mustapha, D. Khandekar, Swati Lele, P. Kamat, S. Sawant, R. Jadhav, D. Shelke, Shivaji Kolekar, R. G. Atram, R. Yamgar

DOI: Not Available         Access: Open Access Read More

Author(s): Perumal Andal, S. Tamilselvy, P. Indra Priyatharesini

DOI: 10.5958/0974-360X.2018.00509.7         Access: Open Access Read More

Author(s): Pradeep K. Sharma, Sabiha Mansoori

DOI: 10.5958/0974-360X.2019.00358.5         Access: Open Access Read More

Author(s): P. Parvathi

DOI: 10.5958/0974-360X.2018.00072.0         Access: Open Access Read More

Author(s): K. Ishwar Bhat, Apoorva A, Abhishek Kumar, Pankaj Kumar

DOI: 10.5958/0974-360X.2019.00902.8         Access: Open Access Read More

Author(s): Nikeherpianti Lolok, Harlyanti Muthmainnah Mashar, Itma Annah, Ahmad Saleh, Wa Ode Yuliastri, Muhammad Isrul

DOI: 10.5958/0974-360X.2019.00357.3         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Recent Articles