ABSTRACT:
This study was carried out to investigate the effect of a new microbiological preparation Vetom 21.77 containing spore-mycelial biomass of Duddingtonia flagrans on hematological and biochemical parameters of broilers. The drug was administered for 3 months. A total number of 105 five-day-old broilers (Hubbard F15) were allocated to four test groups, where birds received the preparation in doses of 2, 5, 50 and 300 µl/kg bodyweight, and a control group with no treatment. Blood samples were collected 1.5 and 3 months after the beginning of the experiment for biochemical and hematological analysis. According to the results obtained, administration of the microbiological drug was followed by positive changes in the immunity of treated broilers. The preparation seems to have stimulating effect on their metabolic processes. There was no negative effect of the drug on the physiological state of the birds. In the course of the experiment, neither disease indications, nor mortality were detected in the birds, excluding deaths caused by the required slaughter. There were no treatment-related allergic reactions, even at the highest daily dose, as exemplified by almost borderline low eosinophil levels observed in treated broilers over the study period. No clinically relevant results were detected in serum biochemical profile.