Author(s):
Saminathan Kayarohanam, Vetriselvan Subramaniyan, Ashok Kumar Janakiraman, Madhan Kumar S. J
Email(s):
samiveni@gmail.com
DOI:
10.5958/0974-360X.2019.00597.3 
Address:
Saminathan Kayarohanam1, Vetriselvan Subramaniyan2, Ashok Kumar Janakiraman 3,
Madhan Kumar S. J4
1Faculty of Bio-economy and Health Sciences, Geomatika University College Kuala Lumpur, Malaysia 54200
2Department of Pharmacology, Faculty of Medicine, MAHSA University, Malaysia 42610
3Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia 56000
4Faculty of Medicine and Health Sciences, UCSI University, Kuala Lumpur, Malaysia 56000
Published In:
Volume - 12,
Issue - 7,
Year - 2019
ABSTRACT:
Aim: To investigate the antioxidant, antidiabetic, and antihyperlipidemic activities of Dolichandrone atrovirens in albino wistar rats. Methods and Material: Bark and leaf part of Dolichandrone atrovirens were extracted with water and methanol. Swiss albino wistar rats were used to evaluate the in vivo effects of streptozotocin induced body weight loss, oxidative stress, hyperglycemia and hyperlipidemia. Statistical analysis used: Data were analysed by One - way ANOVA, followed by Turkey –Kramer Multiple Comparison Test. Results: Dolichandrone atrovirens extract treated animals demonstrated significant increase in body weight, decreased blood glucose levels, glycosylated haemoglobin and changes in other biochemical parameters levels when compared to diabetic control rats.
Cite this article:
Saminathan Kayarohanam, Vetriselvan Subramaniyan, Ashok Kumar Janakiraman, Madhan Kumar S. J. Antioxidant, Antidiabetic, and Antihyperlipidemic Activities of Dolichandrone atrovirens in Albino Wistar rats. Research J. Pharm. and Tech. 2019; 12(7): 3511-3516. doi: 10.5958/0974-360X.2019.00597.3
Cite(Electronic):
Saminathan Kayarohanam, Vetriselvan Subramaniyan, Ashok Kumar Janakiraman, Madhan Kumar S. J. Antioxidant, Antidiabetic, and Antihyperlipidemic Activities of Dolichandrone atrovirens in Albino Wistar rats. Research J. Pharm. and Tech. 2019; 12(7): 3511-3516. doi: 10.5958/0974-360X.2019.00597.3 Available on: https://rjptonline.org/AbstractView.aspx?PID=2019-12-7-72